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Query: UMLS:C0002962 (angina)
 21,142 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Congenital anomalies of the coronary arteries are relatively uncommon conditions with an incidence of approximately 2% in the adult population. Although less common than acquired coronary artery disease, these anomalies may be associated with myocardial ischemia and its consequences; angina, arrhythmia, infarction, and sudden death. A 21-year-old female patient with no significant prior medical history was found dead at home. Postmortem examination revealed high take-off of the right coronary artery with acute down-ward angulation of the proximal right coronary artery and acute downward angulation of the left main coronary artery. Microscopic examination revealed global myocardial ischemia consistent with a terminal ventricular dysrhythmia. There was no evidence of any other disease processes. Detailed toxicological investigation was negative. The Regional Forensic Pathology Unit experience with sudden death due to congenital coronary artery anomalies is presented along with a review of the current literature.
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PMID:Sudden death due to coronary artery anomalies: a case report and clinical review. 811 4

Congenital anomalies of the coronary circulation have been associated with significant cardiac consequences, ranging from angina pectoris to sudden death in otherwise healthy individuals, yet neither systematic evidence nor published guidelines exist to guide cardiologists in the care of such patients. Three cases of coronary anomalies that were detected incidentally in the course of routine cardiac catheterization are presented. Although none of the patients presented suffered complications as a direct result of their coronary anomaly, little is known about the long term effects. A significant number of coronary anomalies are discovered incidentally; however, many remain undetected until they lead to a serious cardiac event. Therefore, more studies are needed to determine which congenital coronary anomalies carry serious cardiac risks, and which are relatively benign. This could lead to the development of guidelines for practitioners in the management of such patients.
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PMID:Congenital anomalies of the coronary circulation. 1533 46

Congenital anomalies of coronary arteries, albeit rare, may be significant contributors to angina pectoris, hemodynamic abnormalities, and sudden cardiac death. A 47-year-old man referred to us with atypical chest pain. Electrocardiography demonstrated no significant ischemic changes, but cardiac troponin I test was positive. The patient underwent coronary angiography, which revealed a single coronary artery from the left Valsalva sinus. In addition, the left anterior descending (LAD) and the left circumflex (LCx) arteries were in normal position with significant stenosis in the mid-portion of the LAD and the distal portion of the LCx. A large branch originated from the distal portion of the LCx and tapered toward the proximal portion as the right coronary artery (RCA). This is a rare coronary anomaly that has no ischemic result. Coronary lesions were the cause of the patient's angina pectoris. Angioplasty and stenting of the LAD and LCx was done, and medical therapy (Clopidogrel, Aspirin, Atorvastatin, and Metoprolol) was continued. The patient was asymptomatic at 8 months' follow-up.
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PMID:Single coronary artery with anomalous origin of the right coronary artery from the distal portion of left circumflex artery: a very rare case. 2439 67

Congenital anomalies of the coronary artery causing coronary occlusive disease may be of many different types. A 67-year-old woman with no coronary risk factors was referred for coronary angiography with few months' history of angina. The patient underwent coronary angiography due to ischemic cardiac symptoms with nondiagnostic exercising test. In coronary angiography, the left main coronary artery was arising from normal anatomical position; however, left anterior descending artery and circumflex artery were hypoplastic. The treatment of patient was discussed in cardiology-cardiovascular surgery council and coronary surgery was found inappropriate due to the hypoplasia of the left coronary system entirely.
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PMID:Left Main Coronary Artery Hypoplasia in Elderly. 2704 96