Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0002962 (angina)
21,142 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a histopathological analysis of the palatine tonsils resected in 70 patients (28 adults and 42 children) with persistent angina, several Langhans'-type giant cells without epithelioid granuloma were detected in the serial specimens of all tonsils from 3 adult patients with pustulosis palmaris et plantaris. By contrast, in the tonsils of the other 67 patients, without pustulosis palmaris et plantaris, only a few atypical multinucleated giant cells including those of foreign body type were found, in the serial specimen of 4 cases. On the basis of these results, the appearance of Langhans'-type giant cells in the tonsil should be noted in persistent angina with pustulosis palmaris et plantaris.
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PMID:Multinucleated giant cells in the palatine tonsil of three patients with pustulosis palmaris et plantaris. 658 62

We report a case of a patient complaining of severe chest pain which required a differential diagnosis between cardiovascular disease and sternocostoclavicular hyperostosis. The patient was a 61-year old male who began experiencing pain across both scapulas at the end of September, 1990. He was admitted to our hospital when the pain extended to the back and anterior chest areas. Examination on admission revealed inflammation with a white blood cell count at 11,800/mm3, an erythrocyte sedimentation rate of 136 mm/hr, and CRP at 14.2 mg/dl. Angina pectoris was suspected based on findings from coronary arteriography which showed 60% stenosis at Seg 6. A Ga-scintigram conducted to determine the cause of the chest pain revealed accumulations in the upper mediastinum. CT and MRI both showed hyperostosis of the sternum, and bone scintigram confirmed marked accumulations in the same area. Palmoplantar pustulosis (PPP) was also clearly noted on the palms and soles of the feet. Sternocostoclavicular hyperostosis was diagnosed based on these findings. Sternocostoclavicular hyperostosis was suspected in this case based on the clinical findings, inflammatory state, and accumulations revealed by bone scintigraphy. However, the diagnosis could have been more conclusive if non-suppurative hyperosteostic osteomyelitis were observed by bone biopsy. A differential diagnosis for unknown sources of chest pain should be considered in cases such as this.
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PMID:[A case of a patient with sternocostoclavicular hyperostosis complaining of severe chest pain, which must be distinguished from cardiovascular disease]. 846 35