Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0002962 (angina)
 21,142 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A systematic study of 100 elderly patients in a hospital geriatric unit was undertaken to analyse the relationship between clinical cardiovascular events (angina, myocardial infarction, hypertension, cerebrovascular accidents, temporo-spatial disorientation, invalidity, incontinence) and plasma lipids (total cholesterol, HDL and LDL fractions, triglycerides, apolipoprotein A and B and total cholesterol/HDL and apolipoprotein B/A ratios). The average triglyceride and apolipoprotein A concentrations were related to the patient's validity: The triglycerides were significantly higher in the group of invalid patients (+22%), p = 0.05. The apolipoprotein A levels were significantly lower in the invalid group (-12%), p = 0.05.
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PMID:[Assays of apolipoproteins A and B as atherogenicity factors in aged patients at hospitals]. 266 Jun 51

For three years we studied the mortality and functional situation of all patients admitted in 1991 to the Neurology Service suffering from acute stroke with the exception of subarachnoid haemorrhage cases. We analyzed the cause of death whether directly related to the initial illness or not. Out of 134 patients admitted for acute stroke, 48 (41.02% of the 117 patients examined after excluding 17 whom we did not obtain complete information from) had died after three years. The main causes of death were directly related to acute stroke (37.5%) and pneumonia (37.5%). Death occurred mainly in the first month (79.16% of deaths). Predictive variables for mortality directly related to acute stroke during the first month include severe weakness, brain haemorrhage, dysphasia and earlier incidence of acute stroke. Variables related to higher mortality rate due to other causes in the first month were dysphasia, age and angina antecedents, whereas earlier incidence of acute stroke was associated with a lesser mortality rate for these causes, as distinct from acute stroke itself. Greater levels of weakness and sphincteral incontinence are the best predictive signs of dependency functional situation at the end of the first month and, along with diabetes, after one and three years.
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PMID:[3 year survival in patients hospitalized for acute cerebrovascular disorders]. 871 89

During the period from July 1995 to June 1996 we performed transurethral resection of the prostate (TURP) on 824 patients with benign prostatic hyperplasia (BPH). Among them, 13 were dementia patients between 74 and 96 years old; they presented with urinary hesitancy in 6, retention in 4, frequency in 2 and incontinence in 1 patient. Past history included stroke in 7, hypertension in 6, pulmonary tuberculosis in 4, diabetes in 3, asthma in 2, angina pectoris in 1, Parkinson's disease in 1, pneumonia in 1, and hepatitis in 1. Careful preoperative examination revealed that they were proper candidates for TURP. They underwent TURP under spinal anesthesia. The mean operative time was 34 min, ranging from 20 to 60 min. The adenoma resected weighed 24 g on the average, ranging from 7.5 to 48 g. During surgery, although hypotension was noted in 2 patients, there was no serious morbidity. Their mental condition was well controlled with ketamine and diazepam during and after surgery. Postoperative complications included acute myocardial infarction in 1, multiple gastric ulcer in 1, and decubitus in 1. None died within 3 months after TURP, 3 died there after, and 10 patients were alive at the mean follow-up period of 26 months. Six patients reported good urination, 3 reported some improvement in urination after surgery, although requiring intermittent catheterization and 1 developed mild incontinence. In conclusion, TURP appears to provide some benefit in selected patients with dementia and should not be considered to be a contraindication for such patients.
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PMID:[Transurethral resection of the prostate for patients with dementia]. 1036 42

Emerging clinical application of electrical stimulation in three systems is reviewed. In the bladder, stimulation of sacral posterior roots reduces reflex incontinence and significantly improves bladder capacity. With the combination of anterior and posterior root stimulation, bladder control can be achieved without the need for rhizotomy. Preliminary research demonstrates that bladder contractions may also be generated by stimulation of the urethral sensory branch of the pudendal nerve, even after acute spinal cord transection, while inhibition of the bladder and control of urge incontinence can be achieved by stimulation of the whole pudendal nerve. Spinal cord stimulation can modulate the activity of the intrinsic cardiac nervous system involved in the regulation of regional cardiac function and significantly reduce the pain associated with angina pectoris. Finally in the area of upper airway disorders, functional electrical stimulation has great potential for increasing life support as well as for quality of life in chronic ailments, particularly obstructive sleep apnea and dysphagia.
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PMID:Emerging clinical applications of electrical stimulation: opportunities for restoration of function. 1176 72

Spinal cord stimulation (SCS) is a neuromodulation technique using electricity, proposed for the first time by Shealy in 1967, as an alternative to neuroablation. Technological improvements in the last 20 years (percutaneous electrodes, single and dual leads, octopolar electrodes, high energy internal pulse generators) have allowed to obtain good results with SCS in various clinical situations of chronic pain. The main clinical indications to SCS are: vascular pain--refractory angina and peripheral vascular diseases (PVD); rachidian pain--failed back surgery syndrome (FBSS), degenerative low back leg pain (LBLP), nerve root lesions, incomplete spine lesions, spinal stenosis; neuropathic pain; chronic regional pain syndrome (CRPS) type 1 and type 2; perineal pain and urological diseases (urge-incontinence, interstitial cystitis). There are important differences between Europe and USA in the SCS use in various indications, especially about PVD. Really, in Europe this technique has been widely used and, finally, there are prospective studies establishing the utility of SCS in: limb survival; pain control; regression to Fontaine stage II; improvement of free interval of claudication. All of this is going to change the attitude towards SCS in USA, where the amputation incidence for critical ischaemia is considerably higher than in Europe. An indication to SCS not very mentioned in literature and that seems to have good results is LBLP due to acquired or mixed (constitutional-acquired) spinal stenosis. In this situation SCS seems to improve notably pain control and quality of life index of patients.
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PMID:Spinal cord stimulation. 1601 21

The rechargeable battery-powered bion microstimulator is designed to bring neurostimulation to mainstream medicine and improve the quality of life of those suffering from neurological disorders. The bion, through direct electrical stimulation of excitable tissues, is intended to treat numerous disorders including urinary urge incontinence, fecal incontinence, chronic headaches, peripheral pain, angina and obstructive sleep apnea. The rechargeable bion microstimulator, manufactured by Advanced Bionics Corporation, is designed to be implanted using a minimally invasive approach that would appeal to clinicians of different specialties as well as patients suffering from a wide variety of debilitating conditions. The bion is currently in clinical trials for the treatment of urinary urge incontinence and headaches. Other clinical trials are expected to follow in the future.
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PMID:Rechargeable battery-powered bion microstimulators for neuromudulation. 1727 Dec 28