Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0002895 (sickle cell disease)
 11,747 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
SCD 0.089
hemoglobin 0.008
BCL11A 0.003
gamma-globin 0.001
HBB 0.001
beta-globin 0.001
HBS1L 0.001
FASN 0.001
stearoyl-CoA desaturase 0.001
HBG2 0.001
ACACA 0.001
erythroid 0.001
beta globin 0.000
BCAM 0.000
methemoglobin 0.000
INSIG1 0.000
HBG1 0.000
FADS2 0.000
AGPAT6 0.000
SREBF1 0.000
basal cell adhesion molecule 0.000
gamma globin 0.000
mitochondrial intermediate peptidase 0.000
KLF1 0.000
ICAM-4 0.000
ACSS2 0.000
LPIN1 0.000
Stearoyl-CoA desaturase 0.000
SREBP-1c 0.000
FAS 0.000
GPAM 0.000
LCE 0.000
ferritin 0.000
FADS1 0.000
Lutheran blood group glycoprotein 0.000
OR51B5 0.000
SCD2 0.000
vascular endothelium 0.000
SEC31B 0.000
OR51B2 0.000
FABP4 0.000
ACSL1 0.000
LW blood group 0.000
SCD1 0.000
KCC1 0.000
gamma-globin chain 0.000
Lutheran glycoprotein 0.000
B19 0.000
RHCE 0.000
DGAT2 0.000
SREBP-1 0.000
OR51B6 0.000
BRI3BP 0.000
Gamma globin 0.000
ACBD7 0.000
RAB3IL1 0.000
POLR3H 0.000
C10orf71 0.000
FERM and PDZ domain-containing protein 4 0.000
DGAT1 0.000
BTN 0.000
FABP3 0.000
MYB 0.000
PPARG 0.000
HAO2 0.000
HELO1 0.000
AGPAT1 0.000
alpha globin 0.000
Adipose differentiation-related protein 0.000
thyroid hormone responsive 0.000
ELOVL5 0.000
NPEPL1 0.000
TOR2A 0.000
PTPLB 0.000
stearoyl-CoA desaturase 5 0.000
LPL 0.000
GOLGB1 0.000
hemopexin 0.000
SCD5 0.000
ELOVL7 0.000
more...
Disease
sickle cell disease 1.000
SCD 0.081
acute chest syndrome 0.037
hemoglobinopathies 0.021
thalassemia 0.018
sickle cell crisis 0.009
priapism 0.003
blood disorder 0.002
HBB 0.001
HBB 0.001
HBB 0.001
beta thalassemia 0.001
Sickle cell nephropathy 0.001
hemolytic anemia 0.001
anemia 0.001
Hb SC disease 0.001
thalassemia major 0.001
Sickle cell trait 0.001
leg ulcers 0.001
iron overload 0.001
hereditary persistence of fetal hemoglobin 0.001
hereditary spherocytosis 0.001
Salmonella osteomyelitis 0.001
alpha thalassemia 0.000
sickle thalassemia 0.000
stroke 0.000
pulmonary hypertension 0.000
Splenic sequestration 0.000
Sickle cell retinopathy 0.000
thalassemia trait 0.000
G6PD deficiency 0.000
osteomyelitis 0.000
dactylitis 0.000
hyposplenism 0.000
LFSS 0.000
Functional asplenia 0.000
fat embolism 0.000
HPFH 0.000
genetic disorder 0.000
moyamoya 0.000
Alloimmunization 0.000
Gamna 0.000
Cardiac siderosis 0.000
malaria 0.000
gallstones 0.000
Hb-C disease 0.000
myelodysplastic anemia 0.000
Bellini duct carcinoma 0.000
Other hemoglobinopathies 0.000
Torulopsis infection 0.000
Hepatic vascular disorders 0.000
Tonsillar actinomycosis 0.000
retinopathy 0.000
FAS 0.000
chronic pain 0.000
splenic infarction 0.000
hemosiderosis 0.000
HbS-HbD disease 0.000
Hemoglobin SE disease 0.000
angioid streaks 0.000
congenital hemolytic anemia 0.000
vascular obstruction 0.000
Parvovirus B19 infection 0.000
iron deficiency 0.000
Pneumococcal sepsis 0.000
parvovirus 0.000
renal disease 0.000
Nocardia sepsis 0.000
Infective spondylitis 0.000
paroxysmal nocturnal hemoglobinuria 0.000
thalassemia minor 0.000
hypersplenism 0.000
cystic fibrosis 0.000
dehydration 0.000
Chronic pain syndrome 0.000
Hemolytic transfusion reaction 0.000
SAD 0.000
acute osteomyelitis 0.000
graft-versus-host disease 0.000
Ataxic dysarthria 0.000
more...
Symptom
pain 0.000
acute pain 0.000
Girdle pain 0.000
splenomegaly 0.000
Reticulocytosis 0.000
Painless hematuria 0.000
bone pain 0.000
Rebound tenderness 0.000
Frequent headaches 0.000
liver pain 0.000
Penile pain 0.000
Other pain 0.000
hepatomegaly 0.000
abnormal breath sounds 0.000
analgesia 0.000
painful erections 0.000
pallor 0.000
Severe pain 0.000
Thoracic pain 0.000
Injection site pain 0.000
abdominal pain 0.000
Procedural pain 0.000
chest pain 0.000
Pneumobilia 0.000
abnormal taste 0.000
left upper quadrant pain 0.000
hip pain 0.000
headache 0.000
dark urine 0.000
enuresis 0.000
musculoskeletal disability 0.000
generalized pain 0.000
Livedoid 0.000
right upper quadrant pain 0.000
thoracic back pain 0.000
decreased appetite 0.000
respiratory distress 0.000
Signs and Symptoms 0.000
seizures 0.000
PAIN 0.000
bedwetting 0.000
back pain 0.000
acute abdominal pain 0.000
feeling tired 0.000
anesthesia 0.000
hypothermia 0.000
arthralgia 0.000
erythema 0.000
growing pains 0.000
stigma 0.000
shortness of breath 0.000
cardiovascular impairment 0.000
wheezing 0.000
periorbital edema 0.000
Exercise intolerance 0.000
facial droop 0.000
fatigue 0.000
hemiplegia 0.000
Decreased activity 0.000
diarrhea 0.000
dyspnea 0.000
hepatosplenomegaly 0.000
pleuritic chest pain 0.000
Physical findings 0.000
leg cramps 0.000
nocturnal polyuria 0.000
cough 0.000
testicular pain 0.000
lethargy 0.000
prostration 0.000
limb pain 0.000
flank pain 0.000
collapse 0.000
jaw pain 0.000
Neurologic symptoms 0.000
arm weakness 0.000
breakthrough pain 0.000
weakness 0.000
Sedation 0.000
Cushingoid 0.000
more...
Drug
Deferasirox 0.000
Senicapoc 0.000
Celsis 0.000
Cassia seed 0.000
Phosphatidylserine 0.000
Heme 0.000
Colestimide 0.000
Glucose-6-Phosphate 0.000
Elmiron 0.000
Innohep 0.000
Regadenoson 0.000
Dakar 0.000
Deferoxamine mesylate 0.000
Trental 0.000
Hydroxyethylstarch 0.000
Sodium Nitroprusside 0.000
Hemopure 0.000
Atarax 0.000
Sodium phenylbutyrate 0.000
Desferal 0.000
K201 0.000
Poloxamer 188 0.000
Cocoa butter 0.000
Andriol 0.000
Domin 0.000
Desferal 0.000
Aggrastat 0.000
Trenbolone acetate 0.000
Demerol 0.000
VCR 0.000
Nitric Oxide 0.000
Depo-Provera 0.000
Benserazide 0.000
Tropicamide 0.000
Eptifibatide 0.000
Demerol 0.000
Kenyan 0.000
Piracetam 0.000
Eculizumab 0.000
Implanon 0.000
Sodium thiosulfate 0.000
THA 0.000
CAM 0.000
Sodium acetate 0.000
Asthma 0.000
Basiliximab 0.000
Basiliximab 0.000
vitamin E 0.000
Liposyn 0.000
Ara-A 0.000
Cellulose acetate 0.000
Epoetin 0.000
Ora 0.000
Sulphasalazine 0.000
Zileuton 0.000
Filgrastim 0.000
ascorbate 0.000
Vitamin E 0.000
TRM 0.000
Darbepoetin alfa 0.000
Iodixanol 0.000
DNase I 0.000
Tenofovir disoproxil fumarate 0.000
Filgrastim 0.000
Kollidon 0.000
Bosentan 0.000
Bosentan 0.000
AGG 0.000
Abatacept 0.000
Ranibizumab 0.000
Poloxamer 0.000
G-CSF 0.000
Alteplase 0.000
EPI 0.000
Pirfenidone 0.000
Orphan 0.000
Fansidar 0.000
Thioridazine 0.000
G418 0.000
Fansidar 0.000
more...
Enzyme
LPL 0.000
lactate dehydrogenase 0.000
glucose-6-phosphate dehydrogenase 0.000
arginase 0.000
thrombin 0.000
phosphoglyceromutase 0.000
CPT 0.000
CPT 0.000
protein methylase II 0.000
CPT 0.000
ribonucleotide reductase 0.000
heme oxygenase 0.000
biotinidase 0.000
ribonucleotide reductase 0.000
aspartate aminotransferase 0.000
methylenetetrahydrofolate reductase 0.000
methylenetetrahydrofolate reductase 0.000
galactosylhydroxylysyl glucosyltransferase 0.000
BMT 0.000
SNO 0.000
AMPK 0.000
acetyl-CoA carboxylase 0.000
APC 0.000
endonuclease 0.000
GDP-mannose 4,6-dehydratase 0.000
scytalone dehydratase 0.000
alanine aminotransferase 0.000
AMP-activated protein kinase 0.000
cathepsin V 0.000
Delta6-desaturase 0.000
AMPK 0.000
CSAD 0.000
AST 0.000
NADPH oxidase 0.000
NADPH oxidase 0.000
alkaline phosphatase 0.000
uracil phosphoribosyltransferase 0.000
CDP-diacylglycerol synthase 0.000
PRT 0.000
NO synthase 0.000
glyoxalase II 0.000
factor D 0.000
fatty acid desaturase 0.000
LMT 0.000
superoxide dismutase 0.000
C3b inactivator 0.000
DNA methyltransferase 0.000
sphingosine kinase 0.000
catalase 0.000
EC 2.7.7.9 0.000
iodothyronine 5'-deiodinase 0.000
hormone-sensitive lipase 0.000
PDK1 0.000
Rex 0.000
FADS 0.000
acyl-CoA oxidase 0.000
fatty-acid synthase 0.000
UDP-glucuronosyltransferase 0.000
peroxiredoxin 0.000
ceruloplasmin 0.000
xanthine oxidase 0.000
mu-calpain 0.000
guanylate cyclase 0.000
peroxidase 0.000
carboxypeptidase G2 0.000
protein kinase 0.000
cytosine deaminase 0.000
phosphodiesterase 0.000
glutathione peroxidase 0.000
NOS 0.000
ACE 0.000
adenosine deaminase 0.000
AMP-activated kinase 0.000
STK11 0.000
adenosine deaminase 0.000
acyl-CoA synthetase 0.000
TDH 0.000
N-acetylglucosaminyltransferase 0.000
luciferase 0.000
ancrod 0.000
more...
Compound
Hydroxyurea 0.007
Hemoglobin 0.002
HBB 0.001
Bantu 0.001
Benin 0.001
iron 0.000
oxygen 0.000
SAD 0.000
C20H24O3 0.000
C20H24O3 0.000
C20H24O3 0.000
N-Phenylacetyl-L-phenylalanine 0.000
C20H24O3 0.000
C20H24O3 0.000
C20H24O3 0.000
C20H24O3 0.000
nitric oxide 0.000
Cetiedil 0.000
Clin 0.000
C20H24O3 0.000
MCH 0.000
2,3-diphosphoglycerate 0.000
Centrolobine 0.000
Benzenemethanethiol 0.000
C20H24O3 0.000
Tropic acid 0.000
DPG 0.000
DHA ethyl ester 0.000
PTMS 0.000
Clotrimazole 0.000
Nereistoxin 0.000
Phosphatidylserine 0.000
Trichothecin 0.000
Dec 0.000
Jatrophone 0.000
DNA 0.000
DPG 0.000
Stearoyl-CoA 0.000
Heme 0.000
hexyl hexanoate 0.000
Mometasone 0.000
valine 0.000
creatinine 0.000
Angelicin 0.000
Hemin 0.000
Hemin 0.000
Hemin 0.000
Hemin 0.000
CHNO 0.000
Hemin 0.000
DFO 0.000
5-Aza-2'-deoxycytidine 0.000
CPT 0.000
PGD3 0.000
Cholesteryl oleate 0.000
CPT 0.000
LCR 0.000
Cholesteryl oleate 0.000
glutamic acid 0.000
zinc 0.000
2-butoxyethanol 0.000
phytanoyl-CoA 0.000
5-Azacytidine 0.000
Dimethylglycine 0.000
arginine 0.000
Desferal 0.000
Azimilide 0.000
propionyl-carnitine 0.000
Ceftriaxone 0.000
glutamine 0.000
SSD 0.000
PPBP 0.000
tropic acid 0.000
Phthalimide 0.000
Tetrahydrouridine 0.000
ethyl propiolate 0.000
Desmosine 0.000
sodium 0.000
Cyanate 0.000
Phenylethanolamine 0.000
more...