Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0002895 (
sickle cell disease
)
11,747
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
SCD
0.089
hemoglobin
0.008
BCL11A
0.003
gamma-globin
0.001
HBB
0.001
beta-globin
0.001
HBS1L
0.001
FASN
0.001
stearoyl-CoA desaturase
0.001
HBG2
0.001
ACACA
0.001
erythroid
0.001
beta globin
0.000
BCAM
0.000
methemoglobin
0.000
INSIG1
0.000
HBG1
0.000
FADS2
0.000
AGPAT6
0.000
SREBF1
0.000
basal cell adhesion molecule
0.000
gamma globin
0.000
mitochondrial intermediate peptidase
0.000
KLF1
0.000
ICAM-4
0.000
ACSS2
0.000
LPIN1
0.000
Stearoyl-CoA desaturase
0.000
SREBP-1c
0.000
FAS
0.000
GPAM
0.000
LCE
0.000
ferritin
0.000
FADS1
0.000
Lutheran blood group glycoprotein
0.000
OR51B5
0.000
SCD2
0.000
vascular endothelium
0.000
SEC31B
0.000
OR51B2
0.000
more...
Disease
sickle cell disease
1.000
SCD
0.081
acute chest syndrome
0.037
hemoglobinopathies
0.021
thalassemia
0.018
sickle cell crisis
0.009
priapism
0.003
blood disorder
0.002
HBB
0.001
HBB
0.001
HBB
0.001
beta thalassemia
0.001
Sickle cell nephropathy
0.001
hemolytic anemia
0.001
anemia
0.001
Hb SC disease
0.001
thalassemia major
0.001
Sickle cell trait
0.001
leg ulcers
0.001
iron overload
0.001
hereditary persistence of fetal hemoglobin
0.001
hereditary spherocytosis
0.001
Salmonella osteomyelitis
0.001
alpha thalassemia
0.000
sickle thalassemia
0.000
stroke
0.000
pulmonary hypertension
0.000
Splenic sequestration
0.000
Sickle cell retinopathy
0.000
thalassemia trait
0.000
G6PD deficiency
0.000
osteomyelitis
0.000
dactylitis
0.000
hyposplenism
0.000
LFSS
0.000
Functional asplenia
0.000
fat embolism
0.000
HPFH
0.000
genetic disorder
0.000
moyamoya
0.000
more...
Symptom
pain
0.000
acute pain
0.000
Girdle pain
0.000
splenomegaly
0.000
Reticulocytosis
0.000
Painless hematuria
0.000
bone pain
0.000
Rebound tenderness
0.000
Frequent headaches
0.000
liver pain
0.000
Penile pain
0.000
Other pain
0.000
hepatomegaly
0.000
abnormal breath sounds
0.000
analgesia
0.000
painful erections
0.000
pallor
0.000
Severe pain
0.000
Injection site pain
0.000
Thoracic pain
0.000
abdominal pain
0.000
Procedural pain
0.000
chest pain
0.000
Pneumobilia
0.000
abnormal taste
0.000
left upper quadrant pain
0.000
hip pain
0.000
headache
0.000
dark urine
0.000
enuresis
0.000
musculoskeletal disability
0.000
generalized pain
0.000
Livedoid
0.000
right upper quadrant pain
0.000
thoracic back pain
0.000
decreased appetite
0.000
respiratory distress
0.000
Signs and Symptoms
0.000
seizures
0.000
PAIN
0.000
more...
Drug
Deferasirox
0.000
Senicapoc
0.000
Celsis
0.000
Cassia seed
0.000
Phosphatidylserine
0.000
Heme
0.000
Colestimide
0.000
Glucose-6-Phosphate
0.000
Innohep
0.000
Elmiron
0.000
Regadenoson
0.000
Dakar
0.000
Deferoxamine mesylate
0.000
Trental
0.000
Hydroxyethylstarch
0.000
Sodium Nitroprusside
0.000
Hemopure
0.000
Atarax
0.000
Sodium phenylbutyrate
0.000
Desferal
0.000
K201
0.000
Poloxamer 188
0.000
Cocoa butter
0.000
Andriol
0.000
Domin
0.000
Desferal
0.000
Trenbolone acetate
0.000
Aggrastat
0.000
Demerol
0.000
VCR
0.000
Nitric Oxide
0.000
Depo-Provera
0.000
Benserazide
0.000
Tropicamide
0.000
Eptifibatide
0.000
Demerol
0.000
Kenyan
0.000
Piracetam
0.000
Eculizumab
0.000
Implanon
0.000
more...
Enzyme
LPL
0.000
lactate dehydrogenase
0.000
glucose-6-phosphate dehydrogenase
0.000
arginase
0.000
thrombin
0.000
phosphoglyceromutase
0.000
CPT
0.000
CPT
0.000
protein methylase II
0.000
CPT
0.000
ribonucleotide reductase
0.000
heme oxygenase
0.000
biotinidase
0.000
ribonucleotide reductase
0.000
aspartate aminotransferase
0.000
methylenetetrahydrofolate reductase
0.000
methylenetetrahydrofolate reductase
0.000
galactosylhydroxylysyl glucosyltransferase
0.000
BMT
0.000
SNO
0.000
AMPK
0.000
acetyl-CoA carboxylase
0.000
APC
0.000
endonuclease
0.000
GDP-mannose 4,6-dehydratase
0.000
scytalone dehydratase
0.000
alanine aminotransferase
0.000
AMP-activated protein kinase
0.000
cathepsin V
0.000
Delta6-desaturase
0.000
AMPK
0.000
CSAD
0.000
AST
0.000
NADPH oxidase
0.000
NADPH oxidase
0.000
alkaline phosphatase
0.000
uracil phosphoribosyltransferase
0.000
CDP-diacylglycerol synthase
0.000
PRT
0.000
NO synthase
0.000
more...
Compound
Hydroxyurea
0.007
Hemoglobin
0.002
HBB
0.001
Bantu
0.001
Benin
0.001
iron
0.000
oxygen
0.000
SAD
0.000
C20H24O3
0.000
C20H24O3
0.000
C20H24O3
0.000
C20H24O3
0.000
C20H24O3
0.000
C20H24O3
0.000
C20H24O3
0.000
N-Phenylacetyl-L-phenylalanine
0.000
nitric oxide
0.000
Cetiedil
0.000
Clin
0.000
C20H24O3
0.000
MCH
0.000
2,3-diphosphoglycerate
0.000
Centrolobine
0.000
Benzenemethanethiol
0.000
C20H24O3
0.000
Tropic acid
0.000
DPG
0.000
PTMS
0.000
DHA ethyl ester
0.000
Clotrimazole
0.000
Nereistoxin
0.000
Phosphatidylserine
0.000
Trichothecin
0.000
Dec
0.000
Jatrophone
0.000
DNA
0.000
DPG
0.000
Stearoyl-CoA
0.000
Heme
0.000
hexyl hexanoate
0.000
more...