Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0002895 (sickle cell disease)
11,747 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein hemoglobin 2400 SCD 1046 Sep 670 erythroid 401 Mol 382 beta-globin 270 ferritin 171 HLA 139 MRI 124 vascular endothelium 122 methemoglobin 116 gamma-globin 116 insulin 114 stearoyl-CoA desaturase 112 lactate dehydrogenase 111 HBB 109 cytokine 108 BCL11A 105 erythropoietin 99 She 82 more...

Disease sickle cell disease 11747 thalassemia 1474 SCD 1046 hemoglobinopathies 809 anemia 804 stroke 778 acute chest syndrome 500 cancer 407 hemolytic anemia 306 malaria 280 diabetes 272 pulmonary hypertension 265 iron overload 238 priapism 216 hypertension 215 ischemia 214 renal disease 191 osteomyelitis 182 sepsis 179 leg ulcers 159 more...

Symptom pain 1063 acute pain 113 splenomegaly 110 analgesia 85 headache 74 abdominal pain 73 anesthesia 71 seizures 70 chest pain 50 hepatomegaly 42 bone pain 41 diarrhea 40 fatigue 39 respiratory distress 35 dyspnea 27 weakness 27 hypothermia 27 cough 24 collapse 24 back pain 24 more...

Drug Cardiovasc 46 Asthma 30 Heme 26 vitamin E 24 Deferasirox 23 lysine 23 ascorbate 23 Dermatol 23 CSF 19 Dakar 18 Phosphatidylserine 14 CAM 14 Nitric Oxide 13 Kenyan 13 DNase I 13 ROS 12 IFN-gamma 10 VCR 10 NADH 10 G-CSF 9 more...

Enzyme lactate dehydrogenase 116 thrombin 79 aspartate aminotransferase 48 glucose-6-phosphate dehydrogenase 47 alkaline phosphatase 45 superoxide dismutase 44 catalase 42 alanine aminotransferase 42 protein kinase 41 peroxidase 37 endonuclease 37 mitogen-activated protein kinase 36 APC 36 ERK 35 LPL 31 arginase 29 AMP-activated protein kinase 28 ACS 27 luciferase 25 AMPK 24 more...

Compound Clin 1118 Dec 785 oxygen 651 DNA 467 iron 446 Hemoglobin 366 Hydroxyurea 313 nitric oxide 308 calcium 147 water 146 sodium 142 glucose 110 HBB 109 creatinine 109 zinc 102 Benin 101 arginine 99 phosphate 93 CO2 71 potassium 69 more...

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