Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0002895 (
sickle cell disease
)
11,747
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Individuals with pain from
sickle cell disease
(
SCD
) are often treated for nociceptive pain, but recent findings indicate they may also have neuropathic pain.
PAIN
Report
It, a computerized version of the McGill Pain Questionnaire, provides a potential subscale that is the summed number of selected neuropathic pain quality words (PR-NNP), but it lacks construct validity. The study purpose was to ascertain PR-NNP construct validity in adults with
SCD
and chronic pain. In an outpatient setting, 186 participants completed the
PAIN
Report
It, Neuropathic Pain Symptom Inventory (NPSI), and Leeds Assessment for Neuropathic Symptoms and Signs (S-LANSS). PR-NNP was moderately correlated with NPSI (
r
= .33,
p
< .001) and S-LANSS (
r
= .40,
p
< .001). Regression analysis indicated that PR-NNP and pain intensity, but not a nociceptive pain subscale, were significant predictors of NPSI and S-LANSS. Findings support construct validity of PR-NNP, which may be useful as a screening tool for neuropathic pain in patients with
SCD
.
...
PMID:Neuropathic Pain Screening: Construct Validity in Patients With Sickle Cell Disease. 3090 May 20
