Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0002895 (sickle cell disease)
 11,747 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 17-year-old-male with Sickle Cell Disease underwent allogenic bone marrow transplant. Two years after the transplant the patient developed violaceous lichenoid papules coalescing into plaques over the face and upper extremities complaining of decrease visual acuity, foreign body sensation, and eye pain. A slit lamp examination showed injected conjunctiva, superficial I punctate keratopathy and decreased baseline Schirmmer test. Dermatologic evaluation and biopsy demonstrated chronic graft versus host disease along with the diagnosis of secondary keratoconjunctivitis sicca.
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PMID:Ocular manifestations of acute graft versus host disease after allogeneic bone marrow transplant. 2506 48