Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0002878 (
hemolytic anemia
)
7,530
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
hemoglobin
772
Sep
485
She
321
erythroid
247
ADAMTS13
171
glucose-6-phosphate dehydrogenase
170
von Willebrand factor
142
pyruvate kinase
129
lactate dehydrogenase
128
Mol
121
haptoglobin
111
methemoglobin
96
interferon
92
erythropoietin
92
B19
85
ATP
85
Glucose-6-phosphate dehydrogenase
75
HUS
67
factor H
64
GSH
64
ferritin
63
IgA
63
X-linked
63
beta-globin
62
ABO
61
G6PD
61
lymphoid
59
LDH
55
CD59
54
ADAMTS-13
54
fibrinogen
52
HLA
50
albumin
49
thrombospondin
47
cytokine
46
CD20
45
TTP
43
metalloprotease
41
membrane protein
41
NADPH
40
prothrombin
40
B12
39
thromboplastin
38
alkaline phosphatase
38
NADP
37
CD55
37
CD4
37
glycoprotein
36
pyrimidine 5'-nucleotidase
35
collagen
34
metalloproteinase
34
transferrin
32
complement factor H
32
IFN
31
Pol
31
ankyrin
31
insulin
30
chronic renal failure
30
CD8
29
membrane cofactor protein
28
triosephosphate isomerase
28
HBB
28
non-Hodgkin's lymphoma
28
MRI
28
von Willebrand factor-cleaving protease
28
ceruloplasmin
27
PKLR
26
granulocyte
26
polypeptide
26
thrombomodulin
25
glutathione synthetase
25
PIG-A
24
CD46
24
hexokinase
23
SLC4A1
23
phosphoglycerate kinase
23
catalase
22
ADP
22
GPI
21
IgG3
21
more...
Disease
hemolytic anemia
7530
thrombocytopenia
1715
anemia
1292
thrombocytopenic purpura
626
hemolytic uremic syndrome
513
systemic lupus erythematosus
384
renal failure
364
TTP
356
acute renal failure
350
sickle cell disease
306
cancer
304
thalassemia
302
autoimmune hemolytic anemia
273
cold
228
G6PD deficiency
224
hereditary spherocytosis
215
hypertension
214
lupus
184
Shiga
153
paroxysmal nocturnal hemoglobinuria
152
disseminated intravascular coagulation
149
malaria
143
neutropenia
140
lupus
140
hyperbilirubinemia
138
tumor
129
renal disease
127
hepatitis
127
rash
118
proteinuria
118
hemoglobinopathies
114
hemoglobinuria
114
autoimmune disease
113
parvovirus
107
leukemia
106
lymphoma
105
idiopathic thrombocytopenic purpura
100
pneumonia
100
lymphadenopathy
98
sepsis
98
Evans
96
methemoglobinemia
96
iron overload
95
aplastic anemia
92
pancytopenia
91
Mycoplasma
91
immunodeficiency
90
renal insufficiency
90
glomerulonephritis
88
purpura
88
vasculitis
87
antiphospholipid syndrome
87
chronic hepatitis
86
cirrhosis
86
chronic lymphocytic leukemia
83
diabetes
82
pulmonary hypertension
82
sepsis
81
stroke
77
arthritis
77
hepatitis C
77
heart failure
75
pyruvate kinase deficiency
75
Hodgkin's disease
73
stomatocytosis
72
myelodysplastic syndrome
71
leukopenia
71
enzyme deficiency
71
renal impairment
70
virus infection
69
ischemia
68
Thrombus
68
rare disease
68
babesiosis
68
HIV
66
rheumatoid arthritis
66
coagulopathy
65
GSH
64
liver disease
64
preeclampsia
61
more...
Symptom
splenomegaly
247
diarrhea
183
abdominal pain
108
fatigue
90
hepatosplenomegaly
87
vomiting
85
pain
75
seizures
68
headache
67
pallor
63
dyspnea
60
weakness
59
erythema
46
anorexia
46
lethargy
39
Ill
37
oliguria
37
arthralgia
35
hepatomegaly
35
respiratory distress
34
nausea
34
regurgitation
33
cyanosis
26
livedo
23
shortness of breath
21
myalgia
20
dark urine
19
dizziness
19
chest pain
17
cough
17
anesthesia
16
collapse
15
chills
14
ataxia
13
tachypnea
12
asthenia
12
back pain
11
chorea
11
syncope
10
hypoproteinemia
9
hemoptysis
9
bone pain
8
fever of unknown origin
8
dysarthria
8
polyuria
8
acute abdominal pain
7
Kayser-Fleischer ring
7
hypotonia
7
night sweats
7
discomfort
7
exertional dyspnea
7
discomfort
7
analgesia
7
tremor
7
acute pain
6
nausea and vomiting
6
sore throat
6
blurred vision
5
vertigo
5
dysuria
5
hypothermia
5
exhaustion
5
abdominal discomfort
4
colic
4
dystonia
4
epigastric pain
4
intestinal bleeding
4
numbness
4
constipation
4
paresis
4
muscle cramps
4
tonic-clonic seizure
4
acute stress
3
skin damage
3
consciousness disturbance
3
cachexia
3
Neurologic symptoms
3
cerebellar ataxia
3
rigors
3
flank pain
3
more...
Drug
Cardiovasc
66
Eculizumab
60
Rituximab
49
Dermatol
39
vitamin E
35
ascorbate
21
Dial
19
Primaquine
19
Asn
18
lysine
16
Glutathione
15
Vitamin E
14
IL-2
13
Nephron
13
Nephron
12
Heme
12
CTX
11
Methyldopa
9
CSF
9
G-CSF
9
Prednisone
9
Rasburicase
9
Rasburicase
9
ampicillin
8
Methylene blue
8
Tacrolimus
7
Prednisolone
7
NADH
7
Methylprednisolone
7
Viramidine
6
MDS
6
Horizon
6
Vitamin B12
5
Biopolymers
5
Mitomycin-C
5
Piperacillin
5
Gel
5
Bortezomib
5
Dakar
5
Leaf
4
Fluorescein
4
ROC
4
Artesunate
4
Doxycycline
4
TAC
4
Campath
4
Campath
4
CDP
4
ACT
4
Vitamin K
4
Fludarabine
4
ROS
4
Opana
4
Fructose
4
Efalizumab
3
Efalizumab
3
Aldomet
3
DDAVP
3
Gastro
3
Infliximab
3
Trimethoprim-sulfamethoxazole
3
Asthma
3
DDAVP
3
Infliximab
3
Oxaliplatin
3
PTH
2
Adalimumab
2
THF
2
Antithymocyte globulin
2
Spectrum
2
PMEA
2
Crixivan
2
Bactrim
2
Crixivan
2
DNase I
2
CTC
2
Hyaluronidase
2
TTC
2
Sulofenur
2
caffeine
2
more...
Enzyme
glucose-6-phosphate dehydrogenase
194
lactate dehydrogenase
144
pyruvate kinase
129
thromboplastin
40
alkaline phosphatase
38
ceruloplasmin
30
phosphoglycerate kinase
28
alanine aminotransferase
28
aspartate aminotransferase
27
proteasome
27
glutathione synthetase
26
catalase
26
hexokinase
23
peroxidase
22
phosphoglucose isomerase
21
adenosine deaminase
21
adenosine deaminase
21
adenylate kinase
20
glutathione peroxidase
20
neuraminidase
20
phosphofructokinase
19
5'-nucleotidase
19
ATPase
18
glutathione reductase
18
superoxide dismutase
18
DAT
17
thrombin
16
ERK
15
aldolase
15
focal adhesion kinase
14
CFI
13
inosine triphosphatase
13
BMT
13
renin
12
calcineurin
12
nucleotidase
12
lecithin:cholesterol acyltransferase
11
gamma-glutamyl transpeptidase
11
ACE
11
NQO1
10
C3b inactivator
9
trypsin
9
heme oxygenase
8
APC
7
AST
7
acid phosphatase
7
acetylcholinesterase
7
creatine kinase
7
mitogen-activated protein kinase
6
gamma-glutamylcysteine synthetase
6
carbonic anhydrase
6
uricase
6
glyceraldehyde-3-phosphate dehydrogenase
6
diacylglycerol kinase
6
protein kinase
6
6-phosphogluconate dehydrogenase
6
6-phosphogluconate dehydrogenase
6
lipase
5
phospholipase A2
5
AMP-activated protein kinase
5
peroxiredoxin
5
cholesterol acyltransferase
5
RNA polymerase
5
coproporphyrinogen oxidase
5
porphobilinogenase
5
arginase
5
5-oxoprolinase
5
phosphoglyceromutase
5
aldehyde dehydrogenase
4
NADPH oxidase
4
glyceraldehyde-3-phosphate dehydrogenase
4
triose-phosphate isomerase
4
NADPH-diaphorase
4
DNA polymerase
4
glutathione S-transferase
4
glyceraldehyde-3-phosphate dehydrogenase
4
CD10
4
lysozyme
4
glyceraldehyde-3-phosphate dehydrogenase
4
NO synthase
4
more...
Compound
Clin
811
Dec
533
DNA
302
iron
278
oxygen
176
Hemoglobin
162
His
128
phosphate
120
creatinine
114
glucose
111
sodium
104
water
103
ATP
85
copper
74
GSH
72
GSH
72
urea
62
Ribavirin
51
leucine
49
potassium
48
pyrimidine
47
pyrimidine
47
hydrogen
46
NADP
46
arginine
45
calcium
43
TTP
43
zinc
42
Cardiol
41
NADPH
40
NADPH
40
pentose
38
Asp
37
pentose
37
pentose
37
pentose
37
alanine
36
lysine
36
glucose-6-phosphate
34
acetate
33
nitric oxide
33
methionine
31
sulfate
31
2,3-diphosphoglycerate
29
valine
28
HBB
28
nitrogen
28
ADP
26
CO2
25
prostacyclin
25
SDS
25
PEG
23
DSS
23
cysteine
23
ADP
22
ADP
22
proline
22
Pyruvate kinase
21
DPG
19
MCP
19
hexose
19
Phe
19
galactose
19
DPG
19
hexose
19
tyrosine
19
Dial
19
Primaquine
19
hexose
19
hexose
19
2-butoxyethanol
18
PEG
18
DAT
17
TMA
17
nicotinamide
17
TMA
17
Cyclosporine
16
A 3
16
glutamine
16
glutamic acid
16
more...