Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0002878 (hemolytic anemia)
 7,530 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 63-year-old male had undergone combination chemotherapy including adriamycin, cisplatin, mitomycin C, 5-fluorouracil and vindesine for six months for double cancer of esophagus and stomach. He complained of lassitude during therapy, and laboratory examinations revealed microangiopathic hemolytic anemia, thrombocytopenia and hyperbilirubinemia. Despite administration of prednisolone, dipyridamole and fresh frozen plasma, the patient died six days later. Postmortem examination disclosed multiple microthrombi in the liver, kidney and pancreas. It was presumed that MMC had caused the illness.
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PMID:[Chemotherapy-associated hemolytic uremic syndrome--a case report]. 151 30