Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0002874 (aplastic anemia)
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Human Gene/Protein
140 AA 12.4
HLA class II DRB1 antigen 11.4
H4FN 11.4
DRS-1 11.1
PR domain containing 8 10.8
Carcinoembryonic antigen-related cell adhesion molecule 8 10.4
SLC25A39 10.4
PIG-A 10.4
TINF2 10.3
FAAP100 10.2
HLA DRB1 gene 10.1
HIST1H2BH 10.1
ACTBL2 10.1
Tp120 10.1
PIGA 9.6
DNAJC21 9.5
FANCE 9.5
NHP2 9.4
GIMAP6 9.4
NOLA2 9.2
NOP10 9.2
DKC1 9.2
50 AA 9.1
Formiminotransferase-cyclodeaminase 9.1
Transcobalamin I 9.1
GDNF family receptor alpha 1 9.0
GIMAP4 8.9
dyskerin 8.9
FAAP24 8.9
RAB20 8.8
M-phase phosphoprotein 1 8.8
SH2D1A protein 8.8
UNC-45A 8.8
FANCG 8.8
FANCF 8.8
GPI anchor biosynthesis 8.8
Ribosomal protein S19 8.7
SRP72 8.6
BCORL1 8.5
FANCB 8.5
more...
Disease
erythrogenesis imperfecta 12.4
aplastic anemia 12.4
Drug-induced gynaecomastia 12.4
Non-A, non-B, non-C hepatitis 12.4
Drug-induced aplastic anemia 12.4
Infection in marrow transplant recipients 12.4
Revesz syndrome 11.5
Acute uveitis 11.4
von Willebrand disease type 2 11.4
Acute disseminated candidiasis 11.4
Megakaryocytic hypoplasia 11.4
Dihydrofolate reductase deficiency 11.4
Amegakaryocytic thrombocytopenia 11.0
Acquired aplastic anemia 10.8
Monosomy 7 syndrome 10.8
panmyelophthisis 10.7
congenital aplastic anemia 10.6
Secondary anemia 10.5
Candida granuloma 10.4
myelodysplastic anemia 10.4
congenital amegakaryocytic thrombocytopenia 10.3
paroxysmal nocturnal hemoglobinuria 10.1
Cutaneous toxoplasmosis 10.1
stage IV chronic lymphocytic leukemia 10.1
dyskeratosis congenita 10.0
colon growth 9.8
gray syndrome 9.8
Polymorphic PTLD 9.8
Refractory heart failure 9.8
Opportunistic mycoses 9.8
Juvenile fibroadenoma 9.6
chronic undifferentiated schizophrenia 9.6
Congenital thrombocytopenia 9.6
Idiopathic aplastic anemia 9.6
Compensated hypothyroidism 9.4
acquired hemolytic anemia 9.3
bone marrow disorder 9.2
Disseminated trichosporonosis 9.2
pancytopenia 9.1
Bacillus cereus infection 9.1
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Symptom
Inspiratory dyspnea 9.2
Spastic paraparesis 7.4
epigastric distress 6.8
dark urine 6.6
generalized abdominal pain 5.8
menometrorrhagia 5.1
pallor 5.0
intestinal bleeding 4.7
giddiness 4.7
giddiness 4.7
chills 4.3
lassitude 4.3
right lower quadrant pain 4.1
splenomegaly 4.1
right upper quadrant pain 4.0
bone pain 4.0
loss of taste 3.9
bladder pain 3.8
abdominal fullness 3.7
hepatosplenomegaly 3.6
sore throat 3.6
hepatomegaly 3.4
asthenia 3.3
hyperesthesia 3.3
abdominal cramps 3.3
swollen joints 3.3
ketonuria 3.3
personality change 3.3
hypoproteinemia 3.2
dental pain 3.2
Fluctuation 3.2
persistent cough 3.1
hypertonia 3.1
masculinization 3.1
acute abdominal pain 3.0
exertional dyspnea 3.0
fever of unknown origin 3.0
groin pain 2.8
erythema 2.7
rigors 2.7
more...
Drug
Ancestim 11.4
Antithymocyte globulin 10.7
Mepartricin 8.9
Serum gonadotrophin 8.5
Zonegran 8.2
Carbatrol 8.2
Cefbuperazone 8.1
Remoxipride 8.0
Deferasirox 7.8
MDS 7.5
Campath 7.4
Campath 7.4
Interferon beta-1a 7.4
Fludarabine 7.0
Desmopressin acetate 6.9
Temodal 6.9
Eculizumab 6.8
MZM 6.6
AKM 6.6
Ambisome 6.6
Methylcellulose 6.5
Rufinamide 6.5
G-CSF 6.5
Daclizumab 6.4
Hyoscyamine 6.4
Rocephin 6.2
Timentin 6.2
LCM 6.2
LCM 6.2
Dilantin 6.1
Filgrastim 5.9
Fosphenytoin 5.9
TRM 5.9
Filgrastim 5.7
AmBisome 5.7
Hydroxyethylstarch 5.7
Syrup 5.6
Gabapentin 5.6
Ara-A 5.6
Dipyrone 5.5
more...
Enzyme
BMT 8.1
creatinine iminohydrolase 8.0
phosphoglycolate phosphatase 5.8
cysteine conjugate beta-lyase 5.1
pyridoxal kinase 4.6
thyroid peroxidase 4.6
iduronate-2-sulfatase 4.5
PRPP synthetase 4.5
microsomal epoxide hydrolase 4.3
phosphoglycerate kinase 4.3
caspase-11 4.0
caspase-11 3.9
caspase-4 3.9
matriptase 3.9
GLO 3.7
dihydropteridine reductase 3.7
HCS 3.7
caspase-4 3.7
STR 3.6
granzyme B 3.5
TdT 3.5
matriptase 3.4
TGT 3.4
CYP27A1 3.3
thiopurine methyltransferase 3.3
1-hydroxylase 3.2
15-hydroxyprostaglandin dehydrogenase 3.1
factor C 3.1
asparaginase 3.0
LPL 3.0
DAT 2.9
AGT 2.8
aryl hydrocarbon hydroxylase 2.7
PST 2.7
PHD 2.6
ALDH 2.6
CD13 2.6
ferrochelatase 2.6
MIP 2.5
diacylglycerol kinase 2.4
more...
Compound
Oxymetholone 10.1
Felbamate 10.0
Pipobroman 9.4
Primobolan 9.4
2-phenyl-1,3-propanediol 9.4
atropic acid 9.2
Norethandrolone 8.7
Aminorex 8.3
Diepoxybutane 7.8
Stanozolol 7.7
Cefozopran 7.5
Aminoantipyrine 7.4
Stanozolol 7.4
Stanozolol 7.3
Muconic acid 7.1
Benzene 7.1
Oxcarbazepine 7.1
Diamant 7.0
Ticlopidine 6.9
PPBP 6.8
Mephenytoin 6.8
Methazolamide 6.7
Vigabatrin 6.7
Flucloxacillin 6.4
Anisodamine 6.4
CD 3 6.3
Cyclosporine 6.3
N-phenylacetamide 6.2
DCVC 6.1
Carbimazole 6.1
Danazol 6.1
Thiamphenicol 6.1
Tiagabine 6.1
Busulfan 6.0
Methimazole 6.0
Canthaxanthin 6.0
Sisomicin 6.0
MTX 5.9
KTS 5.9
Nizatidine 5.9
more...