Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0002874 (aplastic anemia)
 5,905 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
HLA 683
Sep 346
granulocyte 241
erythroid 218
hemoglobin 160
erythropoietin 159
granulocyte colony-stimulating factor 150
lymphoid 143
She 140
CSF 116
cytokine 105
CD34 99
thrombopoietin 91
CD8 89
G-CSF 88
CD4 87
human leukocyte antigen 84
B19 79
MDS 77
megakaryocyte 74
CD59 72
granulocyte-macrophage 71
AML 71
Mol 70
interferon 68
granulocyte-macrophage colony-stimulating factor 61
X-linked 59
GM-CSF 56
HLA-A 54
PIG-A 54
IFN 50
ferritin 47
CD55 46
ALL 45
SCT 43
tumor necrosis factor 42
non-Hodgkin's lymphoma 42
stem cell factor 41
HLA-DR 40
SAA 39
ABO 38
IL-3 37
IL-6 36
CML 35
interferon-gamma 34
TNF 32
MLC 32
Fas 31
glycoprotein 31
severe combined immunodeficiency 30
GPI 30
p53 30
CSA 29
thrombopoietin receptor 29
human leucocyte antigen 27
hematopoietic stem and progenitor cells 26
Interleukin-3 26
TERT 25
IFN-gamma 25
granulocyte colony stimulating factor 24
MTX 24
macrophage colony-stimulating factor 24
chronic renal failure 24
hemochromatosis 24
Pseudomonas 23
IL-2 22
gut 21
CD25 21
transferrin 21
insulin 21
Erythropoietin 20
IL-4 19
major histocompatibility complex 19
DRB1 18
interleukin-2 18
perforin 18
DKC1 18
FANCA 18
CFC 18
myeloperoxidase 17
PHA 17
interleukin-6 17
MRI 17
TNF-alpha 16
B12 16
thymus 16
HLA-B 16
FAB 15
PIGA 15
telomeric 15
CD52 15
THC 14
GATA2 14
CD16 14
T cell receptor 14
IgA 14
IL-17 14
X-linked recessive 14
FANCD2 14
c-kit 14
surface antigen 14
MHC 14
lymphokine 14
megakaryocyte growth and development factor 14
dyskerin 14
FANCG 14
telomerase reverse transcriptase 14
TCR 14
Nei 13
GSH 13
CD20 13
CD19 13
osteogenic 13
HLA-DRB1 13
CD14 13
MPL 13
transferrin receptor 13
HLA class I 13
Pol 13
CD56 13
MSD 13
X-chromosome 13
collagen 12
FISH 12
FANCC 12
HLA-D 12
peroxidase 12
EPO 12
TINF2 12
Fas ligand 12
IL-10 12
Cytokine 12
ribonucleoprotein 12
T-bet 11
CD48 11
cryptic 11
CTX 11
cytochrome P450 11
reserved 11
HSC 11
JAMA 10
CD33 10
TPO 10
interleukin 2 10
ATP 10
CD2 10
FK506 10
MSC 10
alkaline phosphatase 10
kit 10
lipopolysaccharide 9
SH2D1A 9
SCF 9
WT1 9
DAF 9
white cell 9
GATA-2 9
DNMT3A 9
membrane protein 9
membrane-bound 9
more...
Disease
aplastic anemia 5905
myelodysplastic syndrome 829
graft-versus-host disease 755
leukemia 753
cancer 535
pancytopenia 514
anemia 505
thrombocytopenia 412
acute myeloid leukemia 396
paroxysmal nocturnal hemoglobinuria 323
neutropenia 269
acute leukemia 249
chronic myeloid leukemia 232
hepatitis 226
lymphoma 222
acute lymphoblastic leukemia 188
Fanconi 166
agranulocytosis 162
dyskeratosis congenita 137
sepsis 127
tumor 122
multiple myeloma 114
hematologic malignancies 103
cytomegalovirus 99
immunodeficiency 97
hemolytic anemia 92
sepsis 92
pneumonia 89
idiopathic thrombocytopenic purpura 89
Hodgkin's disease 87
interstitial pneumonia 83
thalassemia 82
parvovirus 81
Fanconi syndrome 81
fungal infection 79
systemic lupus erythematosus 78
MDS 77
Epstein 74
virus infection 64
refractory anemia 60
dysplasia 59
cirrhosis 56
infectious diseases 55
autoimmune disease 55
rheumatoid arthritis 55
aspergillosis 54
myelofibrosis 53
myeloproliferative disorders 51
non-Hodgkin's lymphoma 51
megaloblastic anemia 50
diabetes 50
sickle cell disease 49
depression 46
AIDS 46
rash 46
viral hepatitis 45
iron deficiency anemia 45
Infection 45
acute hepatitis 44
iron overload 44
SCT 43
hepatitis B 43
chronic lymphocytic leukemia 43
DBA 42
Acute graft-versus-host disease 42
HIV 40
hepatitis C 39
thrombocytopenic purpura 39
thymoma 39
Leukemia 38
leukopenia 36
autoimmune hemolytic anemia 35
epilepsy 34
rare disease 34
renal failure 33
lymphoproliferative disorders 33
infectious mononucleosis 33
SCID 33
lymphoblastic leukemia 32
liver disease 32
MLC 32
thrombocytosis 31
purpura 31
pulmonary fibrosis 31
polycythemia vera 30
carcinoma 30
CSA 29
thalassemia major 29
hemochromatosis 28
hepatitis A 28
myelosuppression 27
immune deficiency 27
arthritis 27
multiple sclerosis 27
chronic lymphocytic leukemia 27
trisomy 8 27
SDS 27
EBV infection 26
hypertension 26
myasthenia gravis 26
veno-occlusive disease 26
Chronic GVHD 26
blood disorder 25
mucormycosis 25
RAEB 25
chronic renal failure 25
lymphadenopathy 24
hemoglobinopathies 24
influenza 24
varicella 24
hypothyroidism 24
chronic hepatitis 24
lymphopenia 24
vasculitis 23
hepatocellular carcinoma 23
acute nonlymphocytic leukemia 23
myeloid leukemia 23
heart failure 22
genetic disorder 22
West 22
hypogammaglobulinemia 22
neuroblastoma 21
lupus 21
breast cancer 21
Graves' disease 21
Acquired aplastic anemia 20
bacteremia 19
Wiskott-Aldrich syndrome 19
severe congenital neutropenia 19
disseminated intravascular coagulation 19
eosinophilia 19
leukemogenesis 19
hyperthyroidism 19
meningitis 18
hemoglobinuria 18
iron deficiency 18
asthma 18
solid tumor 18
tuberculosis 18
PHA 18
acute promyelocytic leukemia 17
glomerulonephritis 17
viremia 17
candidiasis 17
primary myelofibrosis 16
WT1 16
renal disease 16
hemophagocytic lymphohistiocytosis 16
lung cancer 16
erythroleukemia 15
dermatitis 15
squamous cell carcinoma 15
hypersplenism 15
serum sickness 15
Infections 15
idiopathic pulmonary fibrosis 15
Klebsiella 15
encephalopathy 15
blast crisis 15
cystitis 15
more...
Symptom
seizures 49
headache 35
fatigue 35
abdominal pain 35
splenomegaly 32
diarrhea 29
weakness 27
pain 22
nausea 22
vomiting 18
erythema 16
cough 16
chills 16
pallor 15
exhaustion 12
hepatomegaly 11
anesthesia 11
anorexia 11
dyspnea 10
Ill 10
hepatosplenomegaly 10
discomfort 9
bone pain 9
discomfort 9
chest pain 8
arthralgia 7
myalgia 7
respiratory distress 6
sore throat 6
collapse 6
dizziness 6
angina 5
exertional dyspnea 5
sleepiness 5
paresthesia 5
asthenia 5
ataxia 5
vertigo 5
lethargy 5
dark urine 5
shortness of breath 4
tremor 4
intestinal bleeding 4
nausea and vomiting 4
masculinization 4
regurgitation 3
acute abdominal pain 3
fever of unknown origin 3
analgesia 3
dry eye 3
low back pain 3
numbness 2
starvation 2
cyanosis 2
tinnitus 2
dental pain 2
right upper quadrant pain 2
facial pain 2
flank pain 2
flushing 2
insomnia 2
acute abdomen 2
functional recovery 2
hypoproteinemia 2
colic 2
cerebellar ataxia 2
hypertonia 2
spasm 2
neuralgia 2
apathy 1
groin pain 1
giddiness 1
epigastric distress 1
giddiness 1
loss of taste 1
physical appearance 1
lassitude 1
bladder pain 1
stridor 1
oliguria 1
syncope 1
dysarthria 1
dystonia 1
dysuria 1
tonic-clonic seizure 1
Fluctuation 1
abdominal fullness 1
blurred vision 1
ketonuria 1
spasticity 1
generalized abdominal pain 1
menometrorrhagia 1
acidity 1
hemoptysis 1
hoarseness 1
overweight 1
consciousness disturbance 1
personality change 1
hyperesthesia 1
abdominal cramps 1
Inspiratory dyspnea 1
right lower quadrant pain 1
dry skin 1
acute pain 1
swollen joints 1
cachexia 1
epigastric pain 1
rigors 1
wheezing 1
persistent cough 1
nasal congestion 1
neck pain 1
Spastic paraparesis 1
paraparesis 1
Drug
CSF 161
G-CSF 88
MDS 77
Antithymocyte globulin 39
CTX 38
Campath 24
Campath 24
IFN-gamma 23
IL-2 22
Dermatol 18
Fludarabine 11
CTX 11
CTX 11
Deferasirox 8
Gabapentin 8
Eculizumab 7
ampicillin 7
LCM 6
Prednisolone 6
LCM 6
Rituximab 6
lysine 5
AmBisome 5
Tacrolimus 5
Filgrastim 4
Gel 4
Remoxipride 4
Clopidogrel 4
Methylprednisolone 4
Asthma 4
Acyclovir 4
NADH 4
TRM 4
Filgrastim 4
Daclizumab 3
Cardiovasc 3
Monit 3
ABC 3
SBT 3
Fluconazole 3
Hypaque 3
IL-11 3
Spectrum 3
Prednisone 3
Hypaque 3
Growth hormone 2
Phenytoin 2
Methylcellulose 2
CIA 2
Fluorescein 2
Leaf 2
Vitamin B 2
THA 2
Dilantin 2
Ganciclovir 2
Indomethacin 2
ascorbate 2
Itraconazole 2
vitamin E 2
Spectrum 2
Dalteparin 2
Growth hormone 2
Ara-A 1
-deoxyadenosine 1
Carbatrol 1
PTC 1
Dipyrone 1
BLM 1
Reserpine 1
Vitamin E 1
Rufinamide 1
Gleevec 1
Imatinib 1
Rocephin 1
TEL 1
VCR 1
Pemetrexed 1
Fluorescein 1
p75 1
Zonisamide 1
Timentin 1
pyridoxal phosphate 1
Fraction 1
DHT 1
Lenalidomide 1
Desmopressin acetate 1
ROS 1
Mepartricin 1
ROC 1
Tao 1
CFT 1
Fansidar 1
Maltose 1
Ancestim 1
Ipilimumab 1
Sodium nitroprusside 1
Syrup 1
Zinat 1
Micafungin 1
Abatacept 1
Ambisome 1
CDP 1
Trib 1
Caspofungin 1
PCP 1
IPM 1
Photofrin 1
Cefbuperazone 1
MZM 1
Interferon beta-1a 1
Ofloxacin 1
Vitamin K2 1
Fosphenytoin 1
Amifostine 1
THF 1
Voltaren 1
Neoral 1
Diclofenac sodium 1
Portal 1
EE2 1
Tocilizumab 1
ISP 1
RFP 1
Meropenem 1
Glutathione 1
Arsenic trioxide 1
CPZ 1
Glycerol 1
AKM 1
Ginseng 1
Serum albumin 1
ALA 1
Entecavir 1
Honey 1
Mutagen 1
CTRX 1
Guanethidine 1
Pefloxacin 1
Zonegran 1
Adenosine deaminase 1
Temodal 1
Asn 1
Piperacillin 1
Hydrochlorothiazide 1
Entecavir 1
Auranofin 1
Dial 1
Pregabalin 1
HCH 1
Vitamin B12 1
Phosphatidylserine 1
DDAVP 1
uPA 1
Trimethoprim-sulfamethoxazole 1
Serum gonadotrophin 1
Epoetin 1
Meropenem 1
Diamox 1
DHT 1
EDR 1
more...
Enzyme
BMT 133
peroxidase 29
reverse transcriptase 22
alanine aminotransferase 19
thyroid peroxidase 14
alkaline phosphatase 10
aspartate aminotransferase 9
focal adhesion kinase 8
glutathione S-transferase 8
superoxide dismutase 8
phosphoglycerate kinase 8
catalase 8
lactate dehydrogenase 8
ERK 8
carbonic anhydrase 7
granzyme B 7
STR 7
CD10 7
AST 5
MIP 5
NQO1 5
calcineurin 5
thromboplastin 5
mitogen-activated protein kinase 5
tissue plasminogen activator 4
thrombin 4
asparaginase 4
APC 4
plasmin 4
CD13 4
P-glycoprotein 4
caspase-3 4
TdT 4
luciferase 4
RNA polymerase 4
gamma-glutamyl transpeptidase 4
aldehyde dehydrogenase 3
aldehyde dehydrogenase 3
aldehyde dehydrogenase 3
urokinase-type plasminogen activator 3
aldehyde dehydrogenase 3
glucose-6-phosphate dehydrogenase 3
beta-lactamase 3
phospholipase D 3
cholinesterase 3
neuraminidase 3
acetylcholinesterase 3
microsomal epoxide hydrolase 3
aldehyde dehydrogenase 3
DNA polymerase 3
trypsin 3
aryl hydrocarbon hydroxylase 2
DAT 2
protein kinase C 2
ricin 2
glutathione reductase 2
sialidase 2
monoamine oxidase 2
GSK 2
adenosine deaminase 2
proteasome 2
adenosine deaminase 2
neutrophil elastase 2
ATPase 2
LPL 2
transcriptase 2
phosphoglycolate phosphatase 1
MEK 1
protein phosphatase 2A 1
MDP 1
ferrochelatase 1
pyridoxal kinase 1
alcohol dehydrogenase 1
heparinase 1
carboxylesterase 1
pyruvate kinase 1
cytochrome oxidase 1
matriptase 1
GLO 1
protein kinase 1
aconitase 1
MDR 1
isocitrate dehydrogenase 1
thiopurine methyltransferase 1
IKK 1
phosphorylase 1
topoisomerase 1
cathepsin D 1
caspase-11 1
cysteine conjugate beta-lyase 1
topoisomerase 1
endonuclease 1
NADPH oxidase 1
NADPH oxidase 1
caspase-4 1
lipoprotein lipase 1
phosphodiesterase 1
ceruloplasmin 1
ALDH 1
PHD 1
caspase-11 1
hexokinase 1
methylenetetrahydrofolate reductase 1
ALA synthase 1
factor C 1
15-hydroxyprostaglandin dehydrogenase 1
urease 1
phospholipase C 1
xanthine oxidase 1
diacylglycerol kinase 1
polo-like kinase 1 1
PRPP synthetase 1
cdc2 1
TGT 1
matrix metalloproteinase 9 1
phosphatidylinositol 3-kinase 1
PST 1
matriptase 1
iduronate-2-sulfatase 1
ACE 1
renin 1
soluble epoxide hydrolase 1
transglutaminase 1
TSA 1
AGT 1
glutathione peroxidase 1
dihydropteridine reductase 1
hypoxanthine-guanine phosphoribosyltransferase 1
1-hydroxylase 1
CYP27A1 1
complex I 1
HCS 1
elastase 1
methylenetetrahydrofolate reductase 1
isocitrate dehydrogenase 1
beta-galactosidase 1
creatinine iminohydrolase 1
PCP 1
caspase-4 1
succinate dehydrogenase 1
urease 1
Compound
Dec 443
Clin 376
DNA 305
iron 112
benzene 99
Cyclosporine 73
His 48
CAM 43
CTX 38
Benzene 36
oxygen 35
TNF 32
Methotrexate 31
water 30
hydroquinone 29
TBI 28
Felbamate 26
MTX 25
sodium 23
glucose 19
creatinine 17
acetate 16
leucine 16
phenol 15
FK506 15
GSH 14
GSH 14
ITP 13
Thyroid 12
Neurotol 12
nitrogen 11
LTC4 10
ethanol 10
calcium 10
ATP 10
cysteine 9
Isoproterenol 9
toluene 9
Ticlopidine 8
Hemoglobin 8
copper 8
DBA 8
aldehyde 8
PEG 8
HPP 7
Danazol 7
Lamotrigine 7
Ara-C 7
iodine 7
urea 7
Ara-C 7
Optimal 7
Androgen 7
Guo 7
phosphate 7
Vigabatrin 7
arginine 7
Guo 7
PEG 7
DBA 6
Rapamycin 6
Topiramate 6
zinc 6
TCM 6
Cardiol 6
Busulfan 6
DBA 6
Phe 6
retinoic acid 6
hydrogen 6
CO2 6
pyrene 6
tyrosine 6
Prednisolone 6
A 42 6
TCM 6
aldehyde 6
Temozolomide 6
SDS 5
TSH 5
H2O2 5
chromium 5
TMA 5
NADPH 5
sulfate 5
TMA 5
methionine 5
Asp 5
carbonate 5
lysine 5
CAA 5
DIC 5
Oxymetholone 5
Oxcarbazepine 5
galactose 5
NADPH 5
2-phenyl-1,3-propanediol 4
Nitrite 4
Methimazole 4
PAS 4
DRB 4
A 1 4
ammonium 4
Phosphatidylinositol 4
GPT 4
NADH 4
salt 4
silver 4
EDTA 4
potassium 4
DFO 4
TOF 4
Acyclovir 4
EDTA 4
6-12 4
Etanercept 4
CAP 4
TRH 4
Amphotericin B 4
alanine 4
Stanozolol 4
Pac 4
DEAE 4
CAP 4
Triton 4
Methylprednisolone 4
Erythromycin 3
GTP 3
prostaglandin E1 3
acetaldehyde 3
hydroxylamine 3
folinic acid 3
Trimethoprim 3
2,3-diphosphoglycerate 3
MTT 3
threonine 3
Prednisone 3
acetonitrile 3
GSSG 3
TMP 3
ammonia 3
Azathioprine 3
DPH 3
NIDA 3
Stanozolol 3
mercury 3
cGMP 3
Lead 3
glycerol 3
Estrogen 3
serine 3
TMP 3
TCA 3
Stanozolol 3
DPG 3
hydroxylamine 3
androstane 3
Hypaque 3
chloroform 3
DPG 3
more...