Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
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Enzyme
Compound
Query: UMLS:C0002874 (
aplastic anemia
)
5,905
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Carbonic anhydrase
inhibitors used in the treatment of glaucoma, seizure disorders, and hypertension are rarely associated with blood dyscrasias. Several case reports of
aplastic anemia
with use of acetazolamide, and two cases with use of methazolamide, have appeared in the literature. This article describes two cases of
aplastic anemia
, at least one of which was almost certainly induced by the use of methazolamide, and one case of agranulocytosis related to the use of methazolamide.
...
PMID:Aplastic anemia and agranulocytosis in patients using methazolamide for glaucoma. 44 45
Carbonic anhydrase
inhibitors used in the treatment of glaucoma are rarely associated with blood dyscrasias. Several case reports of
aplastic anemia
with use of acetazolamide, and two cases with use of methazolamide, have appeared in the literature. This report documents two cases of
aplastic anemia
, at least one of which was almost certainly induced by the use of methazolamide, one case of agranulocytosis, and two cases of neutropenia related to the use of methazolamide. In each case several weeks to months elapsed between initiation of therapy and onset of reaction. This suggests that changes in patients' general medical condition should be continually monitored when using these drugs.
...
PMID:Blood dyscrasias in patients using methazolamide (neptazane) for glaucoma. 739 40
