Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0002871 (
anemia
)
52,094
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
hemoglobin
7119
erythropoietin
4396
Sep
3301
erythroid
2388
ferritin
2207
She
1233
Erythropoietin
1091
transferrin
1069
chronic renal failure
912
Mol
911
cytokine
671
B12
669
albumin
624
interferon
545
C-reactive protein
534
lymphoid
517
transferrin receptor
491
FANCD2
484
B19
423
CD4
407
EPO
375
insulin
367
alkaline phosphatase
345
lactate dehydrogenase
310
serum albumin
286
glycoprotein
279
Hepcidin
278
IL-6
277
IFN
276
granulocyte
271
FANCA
260
HLA
258
p53
255
BRCA2
231
thymus
229
MRI
227
Pol
225
fibrinogen
225
IgA
220
granulocyte colony-stimulating factor
218
BRCA1
217
LDH
213
CD34
208
gut
205
collagen
202
tumor necrosis factor
197
TNF
197
beta-globin
195
haptoglobin
194
CD8
193
interleukin-6
193
JAK2
177
aspartate aminotransferase
170
ESR
169
ATP
166
hemochromatosis
164
FANCC
163
prothrombin
159
CRP
157
parathyroid hormone
151
megakaryocyte
150
methemoglobin
147
alanine aminotransferase
145
renin
145
ceruloplasmin
140
superoxide dismutase
138
FANCG
136
FANCI
135
transcobalamin II
135
erythropoietin receptor
134
non-Hodgkin's lymphoma
131
cancer susceptibility
129
CD20
129
CSF
126
MDS
126
myeloperoxidase
125
Gen
121
AML
120
glucose-6-phosphate dehydrogenase
120
thromboplastin
119
serum protein
119
melanin-concentrating hormone
118
IL-10
117
FAB
117
G-CSF
116
ubiquitin
116
white cell
112
Ferritin
110
catalase
109
X-linked
108
c-kit
106
GSH
105
Rec
104
reserved
104
granulocyte-macrophage
102
helicase
99
tyrosine kinase
98
growth hormone
94
RAD51
93
TNF-alpha
93
vascular endothelial growth factor
91
glutathione peroxidase
90
FANCD1
89
FANCJ
87
CHOP
86
HFE
86
mTOR
86
por
85
nodal
85
natriuretic peptide
84
FANCM
83
AST
83
ATPase
81
peroxidase
80
GM-CSF
80
ABO
80
rheumatoid factor
79
interferon-alpha
79
polypeptide
78
interferon-gamma
78
intrinsic factor
78
proteasome
77
interleukin-2
77
IFN-gamma
76
IL-2
76
IL-1
74
von Willebrand factor
74
CD5
74
pyruvate kinase
74
factor VIII
74
esterase
72
hereditary hemochromatosis
72
stem cell factor
72
proton pump
71
FAC
71
glucocerebrosidase
71
PEG
71
Cytokine
71
endonuclease
71
ACE
71
SDS
70
Gag
66
CD19
66
caspase-3
66
Bloom syndrome
66
ATM
66
HDL
66
glucagon
65
FANCF
65
thrombopoietin
65
histone
64
env
64
tumor necrosis factor alpha
64
GFR
64
FANCL
64
kit
64
IL-3
64
ATR
63
interferon alpha
63
GATA-1
62
more...
Disease
anemia
52094
cancer
5204
thrombocytopenia
4983
iron deficiency
2862
tumor
2844
Fanconi
2495
malaria
2052
neutropenia
2036
hypertension
1883
leukemia
1461
diabetes
1460
renal disease
1439
myelodysplastic syndrome
1408
iron deficiency anemia
1387
thalassemia
1365
leukopenia
1312
renal failure
1293
hemolytic anemia
1292
malnutrition
1268
chronic renal failure
1251
HIV
1144
heart failure
1056
multiple myeloma
933
immunodeficiency
829
lymphoma
821
sickle cell disease
804
iron overload
777
acute myeloid leukemia
730
pancytopenia
701
AIDS
697
proteinuria
688
lymphadenopathy
688
sepsis
678
carcinoma
674
infectious diseases
658
depression
643
metastases
601
pneumonia
592
sepsis
571
stroke
538
systemic lupus erythematosus
525
aplastic anemia
505
cardiovascular disease
503
breast cancer
496
parvovirus
474
rash
465
thrombocytosis
458
renal insufficiency
456
adenocarcinoma
450
myelofibrosis
431
obesity
420
tuberculosis
396
rheumatoid arthritis
390
uremia
385
anemia of chronic disease
377
lymphopenia
374
cirrhosis
369
congestive heart failure
365
Infection
361
hypercalcemia
352
hemoglobinopathies
350
hepatitis C
349
hepatitis
347
malabsorption
347
autoimmune hemolytic anemia
345
lung cancer
345
megaloblastic anemia
344
abortion
342
celiac disease
336
gastric cancer
330
arthritis
322
eosinophilia
314
dysplasia
309
Hodgkin's disease
303
hookworm
298
acute renal failure
293
osteoporosis
291
chronic lymphocytic leukemia
291
myocardial infarction
288
inflammatory bowel disease
287
vasculitis
286
prematurity
286
West
278
myelosuppression
276
cold
273
DBA
270
coagulopathy
267
virus infection
265
colorectal cancer
261
lymphocytosis
259
polycythemia
256
microcytic anemia
256
ventricular hypertrophy
255
hyperbilirubinemia
255
preeclampsia
250
chronic disease
245
glomerulonephritis
245
liver disease
245
hypoglycemia
244
ischemia
244
hyperparathyroidism
244
agranulocytosis
242
folate deficiency
242
chronic myeloid leukemia
241
disseminated intravascular coagulation
240
squamous cell carcinoma
237
lupus
237
peripheral neuropathy
236
hemochromatosis
233
genetic disorder
232
myeloproliferative disorders
231
chronic hepatitis
229
acute leukemia
227
vitamin B12 deficiency
226
ovarian cancer
222
thrombocytopenic purpura
222
stomatitis
221
heart disease
220
atherosclerosis
220
primary myelofibrosis
220
chronic lymphocytic leukemia
219
thalassemia major
219
pernicious anemia
218
hepatocellular carcinoma
216
non-small cell lung cancer
210
neuropathy
210
graft-versus-host disease
208
wasting
207
myocardial ischemia
206
Crohn's disease
203
rare disease
203
hereditary spherocytosis
200
autoimmune disease
199
bone disease
198
hypothyroidism
197
acute lymphoblastic leukemia
196
refractory anemia
196
cytomegalovirus
196
gastritis
195
dehydration
193
hyperglycemia
187
renal impairment
186
macrocytic anemia
182
cardiomyopathy
182
uterus
181
coma
180
fits
179
leishmaniasis
177
hyperlipidemia
176
B-cell lymphoma
176
renal cell carcinoma
172
lupus
172
Mycoplasma
171
bowel obstruction
170
influenza
170
Plasmodium falciparum malaria
170
hematologic malignancies
169
encephalopathy
167
dysphagia
167
melanoma
167
more...
Symptom
diarrhea
1583
fatigue
1529
splenomegaly
1527
vomiting
1007
abdominal pain
933
pain
921
anorexia
856
nausea
854
hepatosplenomegaly
749
weakness
591
hepatomegaly
514
dyspnea
491
headache
443
anesthesia
348
lethargy
339
pallor
324
cough
287
seizures
273
respiratory distress
262
nausea and vomiting
258
Ill
226
hypoproteinemia
225
cachexia
204
asthenia
204
constipation
202
hemoptysis
197
arthralgia
195
erythema
178
bone pain
160
overweight
149
myalgia
145
dizziness
143
ataxia
125
back pain
124
epigastric pain
113
discomfort
113
chest pain
111
chills
111
discomfort
110
hypothermia
110
emaciation
107
shortness of breath
103
tachypnea
89
exhaustion
86
fever of unknown origin
82
oliguria
75
intestinal bleeding
75
collapse
74
angina
69
decreased appetite
69
colic
69
night sweats
67
insomnia
65
polyuria
63
syncope
62
cyanosis
62
abdominal discomfort
60
sleepiness
56
flank pain
53
regurgitation
47
analgesia
47
paresthesia
44
tremor
41
hypotonia
41
exertional dyspnea
41
paresis
41
acute abdominal pain
40
polydipsia
37
apathy
37
starvation
36
acute abdomen
35
numbness
34
bloating
34
hypercapnia
33
prostration
32
clubbing
32
vertigo
31
low back pain
31
heartburn
31
agitation
28
sore throat
28
pelvic pain
27
dark urine
26
blurred vision
25
hyperoxia
24
dysuria
23
hunger
23
dysarthria
23
leg pain
22
tinnitus
21
Reticulocytosis
21
rigors
21
leg edema
20
flushing
19
abdominal fullness
19
wheezing
18
incoordination
17
muscle cramps
17
tenesmus
17
hemiplegia
17
cerebellar ataxia
17
hoarseness
17
paraparesis
17
consciousness disturbance
16
productive cough
16
hip pain
16
lassitude
16
livedo
15
Wind
15
spasm
15
hot flashes
15
Gastrointestinal symptoms
14
shoulder pain
14
nasal discharge
13
thinning
13
functional recovery
13
chronic cough
13
ophthalmoplegia
12
forgetfulness
12
ENT
12
spasticity
11
urinary frequency
11
hot flushes
11
acute pain
11
hypocapnia
11
rales
11
stomach pain
11
menometrorrhagia
11
dystonia
11
HSA
10
hyperemesis gravidarum
10
pedal edema
10
rhinorrhea
9
chorea
9
tense
9
torticollis
9
hyperemesis
9
dry skin
9
lightheadedness
9
polymyalgia
8
persistent cough
8
Roth spots
8
koilonychia
8
abdominal cramps
8
orthopnea
8
neck pain
8
Physical findings
7
myoclonus
7
labored breathing
7
knee pain
7
tonic-clonic seizure
7
ketonuria
7
loin pain
7
right upper quadrant pain
7
stigma
7
abnormal breathing
6
tingling
6
enuresis
6
retching
6
periorbital edema
6
more...
Drug
Dial
443
Dermatol
247
CSF
186
ascorbate
182
Epoetin
182
Cardiovasc
175
Epoetin alfa
163
Nephron
149
Nephron
142
vitamin E
132
MDS
126
G-CSF
118
Epoetin alfa
109
Darbepoetin alfa
105
IL-2
78
IFN-gamma
74
lysine
73
Vitamin B12
69
Lenalidomide
59
AZT
59
AZT
59
Vitamin A
59
PTH
57
CTX
53
Kenyan
50
Rituximab
48
Monit
43
BLM
42
Dakar
41
CPT-11
41
ROC
41
ALA
40
MAP
38
Leaf
37
Heme
37
Vitamin B
36
ROS
34
Docetaxel
33
ampicillin
33
niacin
31
Imatinib
30
Taxol
30
Spectrum
30
Epoetin beta
29
Prednisolone
28
Tacrolimus
27
lactose
27
ENT
26
Biopolymers
26
Prednisone
25
Norplant
24
Adriamycin
24
Eculizumab
24
Vitamin E
24
caffeine
23
Serum albumin
23
TTC
23
Mutagen
21
Albumin
21
Fludarabine
21
Bortezomib
21
Venofer
20
Etoposide
19
nitroglycerin
19
Everolimus
19
Vinorelbine
18
Ferumoxytol
18
Deferasirox
17
Pemetrexed
17
Phosphatidylserine
17
Norplant
17
Asthma
17
pyridoxal phosphate
17
CTC
17
EE2
17
Methylprednisolone
16
THF
16
CTC
16
Gel
15
Cobalamin
15
NADH
15
Campath
15
Campath
15
Asn
15
EPI
15
Gastro
14
CTX
14
CIA
14
Fansidar
14
Artesunate
14
CTX
14
Fansidar
13
Irinotecan
13
Oxaliplatin
13
TAC
12
Gleevec
12
Tocilizumab
12
Depo-Provera
12
Leucovorin
11
Bevacizumab
11
DNase I
11
IL-1ra
11
Angiotensin II
11
VCR
11
Ethanol
10
Ferrous sulfate
10
Fraction
10
Captopril
10
ADM
10
Vitamin K
9
IL-11
9
Cerezyme
9
Indomethacin
9
Zoledronic acid
9
Zoledronic acid
9
PFA
9
Sorafenib
9
Herceptin
9
Bayer
9
ABC
9
Fluorescein
9
EPA
8
Glutathione
8
Ferrum
8
ddI
8
Ceredase
8
Ringer's solution
8
Imferon
8
Itraconazole
8
Portal
8
Riboflavin
8
CAM
8
Infliximab
8
Infliximab
8
p75
8
Alliance
8
Cerezyme
7
Activin
7
Iron dextran
7
Taxotere
7
Tuberculin
7
Glucagon
7
Levonorgestrel
7
Antithymocyte globulin
7
DDAVP
7
Doxycycline
7
Glucantime
7
Filgrastim
7
IFN-beta
7
Ferrlecit
7
NBT
7
Filgrastim
7
TAT
7
Sulofenur
6
Aztec
6
Erlotinib
6
AmBisome
6
Paraffin
6
Dasatinib
6
Hemopure
6
more...
Enzyme
lactate dehydrogenase
375
alkaline phosphatase
345
alanine aminotransferase
307
focal adhesion kinase
298
ERK
274
aspartate aminotransferase
254
peroxidase
203
ceruloplasmin
171
superoxide dismutase
163
renin
145
catalase
132
glucose-6-phosphate dehydrogenase
130
reverse transcriptase
129
thromboplastin
126
ACE
117
prolyl hydroxylase
109
glutathione peroxidase
93
mitogen-activated protein kinase
89
ATPase
87
creatine kinase
84
AST
83
proteasome
81
pyruvate kinase
74
endonuclease
71
CD10
64
gamma-glutamyl transpeptidase
62
glucocerebrosidase
61
protein kinase
58
PARP
57
thrombin
54
APC
53
transglutaminase
52
glutathione reductase
46
acetylcholinesterase
45
luciferase
45
calcineurin
44
caspase-3
43
DNA polymerase
43
acid phosphatase
42
RNA polymerase
38
topoisomerase
38
topoisomerase
38
BMT
38
neuraminidase
37
ALA synthase
36
CD13
34
cholinesterase
34
delta-aminolevulinic acid dehydratase
33
lysozyme
33
trypsin
33
prostate-specific antigen
32
adenosine deaminase
31
adenosine deaminase
31
ferrochelatase
30
protein kinase C
29
heme oxygenase
28
AOR
28
lipase
26
RNase
23
glutathione S-transferase
23
PHD
23
transcriptase
23
ACS
21
NO synthase
21
RNase
20
MEK
20
lecithin:cholesterol acyltransferase
20
cytochrome oxidase
20
cholesterol acyltransferase
20
phosphofructokinase
20
DAT
19
phosphatidylinositol 3-kinase
19
inosine triphosphatase
19
AMP-activated protein kinase
18
tissue plasminogen activator
17
succinate dehydrogenase
17
porphobilinogen deaminase
17
phosphoglycerate kinase
17
cdc2
16
hexokinase
16
carbonic anhydrase
16
NADPH oxidase
15
hypoxanthine-guanine phosphoribosyltransferase
15
plasmin
15
dUTPase
15
NADPH oxidase
15
NOS
14
CPT
14
dihydrofolate reductase
14
thymidine kinase
14
CYP3A4
14
sorbitol dehydrogenase
14
aldehyde dehydrogenase
14
thyroid peroxidase
14
beta-galactosidase
14
MAP
14
MTD
14
methylenetetrahydrofolate reductase
13
methylenetetrahydrofolate reductase
13
lipoxygenase
12
lipoprotein lipase
12
phosphoglucose isomerase
12
aldolase
12
CPT
12
CPT
12
tryptase
11
phosphoinositide 3-kinase
11
TdT
11
ribonucleotide reductase
11
complex I
11
AMPK
11
CAD
11
sialidase
11
tyrosine hydroxylase
11
CAD
11
CAD
11
P-glycoprotein
11
thymidylate synthase
10
AMPK
10
RNase H
10
hyaluronidase
10
caspase-1
10
Mg2+-ATPase
10
phospholipase A2
10
ribonucleotide reductase
10
MIP
10
asparaginase
10
DNase II
9
methionine synthase
9
hyaluronidase
9
aldehyde dehydrogenase
9
aldehyde dehydrogenase
9
phosphodiesterase
9
xanthine oxidase
9
caspase-8
9
glyceraldehyde-3-phosphate dehydrogenase
9
5'-nucleotidase
9
aldehyde dehydrogenase
9
aldehyde dehydrogenase
9
methionine synthase
9
transketolase
9
glyceraldehyde-3-phosphate dehydrogenase
9
DNase
8
carboxylesterase
8
adenylate kinase
8
urokinase-type plasminogen activator
8
citrate synthase
8
arginase
8
IKK
8
GCA
8
aconitase
7
15-lipoxygenase
7
CPR
7
pyruvate dehydrogenase
7
glucosylceramide synthase
7
glyceraldehyde-3-phosphate dehydrogenase
7
adenylate cyclase
7
ribonuclease
7
ribonuclease
7
NQO1
7
more...
Compound
iron
7674
Clin
4177
Dec
3527
DNA
3069
oxygen
1779
creatinine
1107
Hemoglobin
808
water
772
calcium
702
zinc
600
glucose
598
sodium
531
urea
492
copper
488
His
472
Dial
444
phosphate
413
Cardiol
355
sulfate
311
nitrogen
267
potassium
256
acetate
250
vitamin D
205
TNF
197
phosphorus
195
retinol
189
nitric oxide
181
salt
176
CO2
175
ATP
166
barium
159
iodine
131
PEG
129
homocysteine
126
aluminum
122
arginine
119
MCH
118
GSH
113
GSH
113
selenium
110
AZT
104
Pac
104
hydrogen
103
tyrosine
102
leucine
100
cadmium
99
lysine
98
ethanol
97
methionine
92
alanine
90
2,3-diphosphoglycerate
88
PEG
88
DPG
86
DPG
85
5-FU
84
cysteine
81
Optimal
79
DDP
79
PGA
78
Ribavirin
77
EDTA
76
aldosterone
76
SDS
75
Lead
75
serine
75
EDTA
73
6-12
70
ADP
68
cobalt
67
CBDCA
66
CBDCA
66
threonine
65
galactose
62
manganese
61
A 3
61
MMC
61
Parenteral
60
IDA
59
Vitamin A
59
ANCA
58
tryptophan
57
PAS
56
Gemcitabine
55
Gemcitabine
55
CTX
53
A 71
52
Asp
50
nicotinamide
49
HBB
49
ANA
49
ANA
49
chromium
49
L-carnitine
49
Thyroid
49
retinoic acid
48
BLM
48
ADP
47
pyrimidine
47
DBA
47
Hydroxyurea
47
ADP
47
DBA
46
DBA
46
ALP
46
Phe
46
pyrimidine
46
ASA
45
benzene
44
Insulin
44
carbonate
43
A 42
43
silver
43
CPT-11
41
Heme
40
glutamine
40
Cyclosporine
40
proline
40
hydroxide
40
DIC
39
tryptophan
39
Benin
38
GPT
38
nicotinic acid
38
tryptophan
37
Paclitaxel
37
tryptophan
37
BCR
36
A 1
36
nitrate
36
VP-16
36
Adriamycin
35
aldehyde
35
H2O2
34
Testosterone
34
Rapamycin
34
MDA
34
valine
34
Testosterone
34
Ara-C
34
folinic acid
34
ABL
34
MAP
34
Isoproterenol
33
TSH
33
aceturate
32
CAM
32
Ascorbic acid
32
Gly
32
FK506
32
ammonium
31
ammonia
31
Ile
31
neopterin
30
Guo
30
Docetaxel
30
DSS
29
Vitamin D
29
Guo
29
glutamate
29
Prednisone
29
more...