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Query: UMLS:C0002871 (anemia)
 52,094 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Access to nutritious food by poor people is being increasingly hindered by the failure of the food security system, and diminishing real income value, in most African countries undergoing Structural Adjustment Programme. Hence, nutritional disorders such as protein energy malnutrition, xerophthalmia, anaemia, low birth weight, stunting and wasting are on in the increase. Although soybean is used in quite a number of African countries as a weaning food, there are still problems such as lack of technical know-how for its processing into infant foods, cultural practices which favour the use of cereal rather than legumes for weaning infants and the long cooking time. In spite of this, the prospects for the crop as infant food is becoming brighter, and some ways of achieving this are discussed.
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PMID:Use, problems and prospects of soybean in infant weaning practices in Africa. 176 13

The nutritional status of a randomly selected sample population has been investigated in Upper Volta in 1978. The estimated mortality rate among the preschool children population (0-5 years) is as high as 39%. Up to 6% of the children 0-9 years old were found to be wasted and stunted. Older children and adults are regularly underweight although their muscular arm circumference is an average acceptable by reference to international standard. The prevalence of anemia in the whole population is round 30% and case of xerophthalmia may be observed in the country.
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PMID:[Nutritional survey in Upper Volta. I. Importance and forms of malnutrition]. 668 54

Four cases of lichen with atrophy of the nail are reported. Three of them had erosive lesions on the sole of the feet. They all had lichen planus of the mouth and some slight lesions of typical lichen planus of the skin too. One of them also had lichen sclerosus of the scalp, and two women had non-atrophic alopecia of the axillary and pubic hair. There were other heterogeneous associated clinical features in all the cases: diabetes in one case; "esophageal diverticula", xerophthalmia, low figures of C.4 and antinuclear antibodies in serum in another case; hyperuricaemia and hypertriglyceridemia a in another case; hepatic cirrhosis and ferropenic anaemia in the other case.
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PMID:[Erosive plantar lichen planus with onycho-atrophy]. 675 6

A total of 14,740 schoolchildren in seven provinces of Shoa Administrative Region in Central Ethiopia were surveyed for the prevalence of goitre, xerophthalmia and anaemia. Haemoglobin and packed cell volume were assessed in 966 children in one province while an in-depth study was conducted on 344 children in the same province and two others. Goitre, xerophthalmia (Bitot's spots) and clinical anaemia were observed in 34.2, 0.91 and 18.6% respectively of the children. Most biochemical variables were within the normal range while those of haemoglobin (Hb), mean corpuscular Hb concentration (MCHC) and urinary I excretion were lower, and mean corpuscular volume, mean corpuscular Hb (MCH), and immunoglobulins G and M were higher. Hb was strongly correlated with retinol, ferritin, MCHC, MCH, packed cell volume and erythrocyte count while retinol formed a triad with transthyretin (TTR) and retinol-binding protein (RBP) which were all correlated with one another. Total and free thyroxin and total and free triiodothyronine were positively correlated as were the concentrations of the total and free hormones. Thyrotropin (TSH) was negatively correlated with total and free thyroxin and positively correlated with free triiodothyronine. Thyroxin and triiodothyronine in both free and combined forms were all correlated with thyroxin-binding globulin which in turn was negatively correlated with the triad retinol, RBP and TTR. The triad was also negatively correlated with C-reactive protein. Urinary I excretion was positively associated with total thyroxin and negatively associated with TSH. The anaemia found was not nutritional in origin but due to the effect of infestation with intestinal parasites and malaria.
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PMID:Interrelationship between vitamin A, iodine and iron status in schoolchildren in Shoa Region, central Ethiopia. 826 Apr 84

The relationship between ocular manifestation of vitamin A deficiency and children's anaemic/morbidity status as well as the efficacy of vitamin A prophylaxis in preventing these conditions was determined. The prevalence of xerophthalmia in morbid children with anaemia and history of worm infestation, measles, and diarrhoea was higher as compared to their non-morbid counterparts. The relative risk (RR) of anaemic children with eye signs was significantly higher (1.5), but the chances of having anaemia were similar in both vitamin A receivers and non-receivers. The RR of history of worm infestation, measles, and severe diarrhoea was 1.4, 1.0, and 1.2, respectively, in children with eye signs and 1.2, 0.8, and 1.3, respectively in children who did not receive vitamin A prophylaxis. The RR for occurrence of diarrhoea along with vitamin A deficiency was as high as 1.9. It appears xerophthalmia and anaemia co-exist and vitamin A supplementation helps in curbing these conditions among 1-6-year-old children.
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PMID:Xerophthalmia, vitamin A supplementation and morbidity in children. 849 70

A survey of 754 preschool children was undertaken in the urban areas of seven small towns of the semi-arid region of Bahia, Northeastern Brazil, to determine the prevalence of vitamin A deficiency, as well as its association with variables such as a age, family income, mother's schooling and dietary adequacy in vitamin A. Protein energy malnutrition and anemia were also studied and are reported separately. The clinical ophthalmological examination did not reveal any signs or symptoms of xerophthalmia amongst these children. In 563 children serum retinol was determined and the average value found was 20.3 micrograms/dl (SD = 10.8 micrograms/dl); the prevalence of deficient serum retinol (below 10.0 micrograms/dl) was of 15.3%. In all 7 localities studied, the prevalence of deficient retinol levels was above 5.0%, the criterion recommended by WHO for considering it a Public Health Problem. The distribution of serum retinol was similar between the sexes, but there was an age trend: the prevalence of deficient and low levels decreased with age. There was no association between deficient serum retinol and family income per capita or mother's education. Results from the 24 h food consumption survey revealed that only 8% of children had an adequate intake of vitamin A through the diet; 66% received less than 1/2 and 35% less than 1/4 of the recommended daily intake of vitamin A. Vitamin A deficiency should be considered a Public Health Problem in the region due to the high prevalence of deficient levels of serum retinol as well as the large dietary inadequacy.
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PMID:[Nutritional status of pre-school children of the semi-arid region of Bahia (Brazil): II--Vitamin A deficiency]. 900 24

Micronutrient malnutrition cannot be eradicated, but the elimination and control of iron, vitamin A and iodine deficiencies and their health-related consequences as public health problems are currently the targets of global programmes. Remarkable progress is occurring in the control of goitre and xerophthalmia, but iron-deficiency anaemia (IDA) has been less responsive to prevention and control efforts. Subclinical consequences of micronutrient deficiencies, i.e. "hidden hunger", include compromised immune functions that increase the risk of morbidity and mortality, impaired cognitive development and growth, and reduced reproductive and work capacity and performance. The implications are obvious for human health and national and global economic and social development. Mixes of affordable interventions are available which, when appropriately adapted to resource availability and context, are proven to be effective. These include both food-based interventions, particularly fortification programmes, such as salt iodization, and use of concentrated micronutrient supplements. A mix of accompanying programmes for infection control, community participation, including education, communication and information exchange, and private sector involvement are lessons learned for overcoming deterrents and sustaining progress towards elimination.
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PMID:Perspectives from micronutrient malnutrition elimination/eradication programmes. 1006 71

This article presents the impact of Integrated Child Development Services (ICDS) on the nutritional status of mothers and of children under 6 years old in India. ICDS is the first and probably the only program in the country that aims at the holistic development of an individual. The reduction in prevalence of severe malnutrition is comparatively more significant in ICDS scheme population than in other population groups. There has been an extensive improvement in the nutritional status of children living in rural, urban and tribal areas and in those belonging to depressed sections of the community. The new initiative schemes for supplementary nutrition include: (a) improved monitoring mechanisms, (b) increased and improved norms of nutrition, (c) improved acceptability of supplementary recipes, (d) care of the severely malnourished, (e) the formation of a state level committee of experts, (f) inspection of quality, and (g) the introduction of community growth charts for malnourished children. The distribution of iron and folic tablets together with megadoses of vitamin A has also been undertaken for iron deficiency anemia and xerophthalmia prevention. Professionals, administrators, and politicians should feel obliged to continue making their contributions to the effective implementation of ICDS.
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PMID:Integrated Child Development Services scheme (ICDS) and its impact on nutritional status of children in India and recent initiatives. 1124 83

Comprehensive recommendations for the assessment and control of vitamin A deficiency (VAD) were rigorously reviewed and revised by a working group and presented for discussion at the XX International Vitamin A Consultative Group meeting in Hanoi, Vietnam. These recommendations include standardized definitions of VAD and VAD disorders. VAD is defined as liver stores below 20 micro g (0.07 micro mol) of retinol per gram. VAD disorders are defined as any health and physiologic consequences attributable to VAD, whether clinically evident (xerophthalmia, anemia, growth retardation, increased infectious morbidity and mortality) or not (impaired iron mobilization, disturbed cellular differentiation and depressed immune response). An estimated 140 million preschool-aged children and at least 7.2 million pregnant women are vitamin A deficient, of whom >10 million suffer clinical complications, principally xerophthalmia but also increased mortality, each year. A maternal history of night blindness during a recent pregnancy was added to the clinical criteria for assessing vitamin A status of a population, and the serum retinol criterion for a "public health problem" was revised to 15% or more of children sampled having levels of <20 micro g/dL (0.7 micro mol/L). Clinical trials and kinetic models indicate that young children in developing countries cannot achieve normal vitamin A status from plant diets alone. Fortification, supplementation, or other means of increasing vitamin A intake are needed to correct widespread deficiency. To improve the status of young infants, the vitamin A supplements provided to mothers during their first 6 wk postpartum and to young infants during their first 6 mo of life should be doubled.
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PMID:Assessment and control of vitamin A deficiency: the Annecy Accords. 1222 Dec 59

The World Health Organization defines health as not only the absence of disease but as a more positive state of physical, mental, and social well-being. 1 of the most important influences on health is nutrition. Millions of people throughout the world either do not get enough to eat or do not get enough of the right kinds of food. Malnutrition is the biggest single contributor to child mortality in developing countries; malnourished children have an impaired ability to fight infection and disease. Children suffering protein-energy or protein-calorie malnutrition may develop nutritional deficiency diseases such as marasmus or kwashiorkor. Some estimates indicate that 2/3 of children in developing countries suffer from protein-calorie malnutrition. Some deficiency diseases caused by a lack of 1 or more nutrients are very widespread, such as anemia, endemic goiter, and xerophthalmia. Contributing factors for malnutrition may include low purchasing power of poor families, poor harvests due to crop failure, bad weather, food spoilage, pests, or a poor distribution system, or cultural practices that prevent the full utilization of available food resources. The decline in the incidence of breastfeeding in recent decades is a major factor in the malnutrition and ill health of children. The quality of nutrition affects the development of human beings in many ways that are sometimes overlooked, such as physical growth and intellectual development. In the long run, only economic development will eliminate malnutrition by eliminating its basic causes of food availability, poverty, ignorance, and overpopulation. Breastfeeding is an important nutritional source for infants and has a contraceptive value for mothers. Improved nutrition should have beneficial effects on the costs of providing education, health services, and housing. Improving the nutritional status of small children may increase their ability to withstand disease, resulting in the survival of greater numbers of children and indirectly exerting negative pressure on the birthrate as parents become more confident of their children's survival.
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PMID:Population, nutrition and health. 1226 59


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