Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0002871 (anemia)
 52,094 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Muscle contraction headache (tension-type headache; MCH) usually begins when a patient is looking down or bending their neck. In the case of MCH patients, EMG activity of the posterior neck muscles at a sitting posture is significantly higher than the controls when the orbito-meatal line is horizontal or bending downward. Comparing with the controls, blood flow of the posterior neck muscle decreases sharply when the head is bent downward. Decrease of the muscle blood flow continues if the muscle is passively contracted. However, in the case of active contraction, blood flow recovers reflexly in 30 seconds. This explains why postural muscle contraction is important. When a patient is ordered to bend her neck down at the orbitomeatal line 30 degrees from horizontal, patient complains of a dull feeling at her posterior neck muscles in 30 seconds. In two minutes dull headache appears at the occipital area, soon becoming more intense and spreading to the forehead and temporal area. Once she looks up, muscle contraction of the neck disappears though she still feels headache. After the local anesthesia is applied to the occipital tender point, her headache disappears completely. From this experiment, MCH is a referred pain from occipital tender point which is the insertion point of occipital neck muscles. Patients with poor stability of cervical bone, and relatively heavy head weight compared with their neck are susceptible to MCH. Psychological stress decreases blood flow of the muscle and aggravates ischemic muscle contraction. Other risk factors include hypotension, anemia, and weak muscle power.
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PMID:[Tension type headache with special reference to muscle abnormality]. 875 91

Fatigue, a common presenting complaint in primary care, is described as a lack of energy, sleepiness, tiredness, exhaustion, an inability to get enough rest, or weakness. Thus, fatigue affects quality of life. The prevalence rate of fatigue among patients with HIV infection is estimated to be 20% to 60%, and as the disease worsens, fatigue may become even more prevalent. The causes of HIV-related fatigue may be multifactorial and may include lack of rest or exercise, or improper or inadequate diet; psychological stress including depression and anxiety; the use of recreational substances; anemia; abnormalities of the thyroid gland and hypogonadism; infections; side effects of medications; sleep disturbances; and fever. This article reviews the common causes of HIV-related fatigue and briefly discusses options for reducing fatigue.
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PMID:Assessment and treatment of HIV-related fatigue. 1156 35

During 1999-2001, Mongolia (2000 population: 2.7 million) experienced consecutive dzuds (i.e., a severe winter with extreme cold and heavy snowfall that causes mass debilitation and death of livestock and jeopardizes the lives of herders who depend on their animals for food, fuel, income, and transportation) that resulted in a loss of nearly six million of the country's 33 million livestock. As a result, severe psychological stress and increased school drop-out rates have been reported, and increased migration of rural herders into urban centers has placed a burden on water, sanitation, medical, and social services. This disaster threatened the health and food security of approximately 40% of the country's population. The Mongolian Ministry of Health asked the World Health Organization (WHO) and the United Nations Children's Fund (UNICEF) for assistance in assessing the nutritional effects of the 2000-2001 dzud on children aged 6-59 months. This report summarizes the results of that assessment, which indicated that affected districts had no excess nutritional wasting in any age group; however, excess growth stunting and anemia were common in both affected and unaffected districts. Expanded monitoring of this population is needed to determine the causes of malnutrition and to develop appropriate interventions.
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PMID:Nutritional assessment of children after severe winter weather--Mongolia, June 2001. 1183 32

Fatigue is a subjective experience that affects everybody. In healthy individuals, it can be considered a physiological response to physical or psychological stress. In people with specific diseases, however, fatigue often represents one of the most significant problems. Fatigue can be caused by many factors, both intrinsic to the patient and extrinsic, such as therapeutic interventions. This review, based on published studies, has been conducted with the aim of presenting a critical discussion of the available information on the characteristics, causes and potential treatments of fatigue in cancer patients receiving chemotherapy. The incidence of fatigue in these patients, the methods for measuring and evaluating fatigue, and possible therapeutic options are discussed. An appraisal of the toxicity of various chemotherapeutic agents is also presented. Although fatigue is now an ever more considered aspect of the toxicity of chemotherapy, it remains difficult to establish what standard should be used to make a quali-quantitative evaluation of this symptom. Furthermore, in the absence of a clear demonstration of the efficacy of some therapies, the management of cancer-related fatigue remains poorly defined (except for the treatment of anemia-related fatigue). New randomized clinical trials are necessary to indicate the best strategies for tackling this important problem.
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PMID:Fatigue in cancer patients receiving chemotherapy: an analysis of published studies. 1536 22

Androgen deprivation therapy for prostate cancer is associated with several complications, including loss of libido, hot flashes, night sweats, psychological stress, osteoporosis, anemia, fatigue, loss of muscle mass, glucose intolerance, and changes in lipid profile. The natural history of prostate cancer while on such therapy is the attainment of an incurable androgen-independent state. Early diagnosis by prostate-specific antigen screening, longer life expectancies, and a penchant for immediate therapy pose a problem where clinicians have to balance the potential benefits of early hormonal therapy with the risks of development of these metabolic and psychological complications. Intermittent androgen deprivation offers clinicians a prospect to improve quality of life in patients with prostate cancer by harmonizing the benefits of androgen ablation with a reduction in treatment-related side effects and expenditure. In this review we discuss the challenges and opportunities of this mode of therapy and shed light on some of the underlying molecular mechanisms.
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PMID:Intermittent androgen deprivation therapy for prostate cancer. 1516 84

Anemia is a widespread public health problem. The psychological stress decreases serum iron level and inhibits erythropoiesis. However, the molecular mechanisms involved, leading to iron mal-regulation are not well known. We used a communication box paradigm to induce psychological stress and found that serum iron level decreased after 3d while liver iron storage increased after 7d. Moreover, psychological stress up-regulated expressions of interleukin-6 (IL-6) and hepcidin, while down-regulating ferroportin expression after 3d. These changes were blocked by the injection of IL-6 monoclonal antibody. In conclusion, the IL-6-hepcidin axis is up-regulated by psychological stress in rats, resulting in hypoferremia and increase of hepatic iron storage.
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PMID:Psychological stress induces hypoferremia through the IL-6-hepcidin axis in rats. 1854 Nov 41

A 59-year-old employed man was recommended to have surgical treatment for symptomatic left middle cerebral arterial stenosis. He refused surgical treatment for social reasons but was given conservative therapy for the prevention of the recurrence of cerebral infarction. Immediately after he retired, he had severe recurrent cerebral infarction with severe anemia and low blood pressure due to gastroduodenal ulcer bleeding. It was inferred from MRI findings that this recurrent cerebral infarction was related to a hemodynamic mechanism and mental stress due to the gastroduodenal ulcer. The influence of occupational mental stress has been reported to be a risk factor of gastroduodenal ulcer. The occupational situation of a patient should be an important factor in consideration of the prevention of cerebral apoplexy.
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PMID:[Pitfall in conservative therapy for working patients with brain ischemia]. 2463 83

"Pandu" Roga is a disease entity described in Ayurveda which has clinical features similar to that of various types of anemia, in which there develops a pale-yellow discoloration on the skin. Besides the various etiological factors, Acharya Charaka has specially described some psychological causative factors among which Chinta (excessive worry), Bhaya (fear) and Shoka (grief) are three main factors, which play an important role in the pathogenesis of Pandu Roga. This paper aims to explore the scientific explanations for the above stated factors in the causation of Pandu Roga (anemia). Hence, a thorough search was made on the internet using the keywords anemia, psychological stress, anger, fear and some scientific studies were found on the concerned topic. It reveal that these factors disturb the process of iron distribution within the body and affects the process of erythropoiesis causing iron deficiency anemia.
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PMID:A review on role of psychological factors in the etiopathogenesis of Pandu Roga with reference to iron deficiency anemia. 2882 50

This study uses biomarker information from the 2013 National Nutrition Survey Afghanistan and satellite precipitation driven modeling results from the Global Flood Monitoring System to analyze how floods affect the probability of anemia in Afghan women of reproductive age (15-49). In addition to establishing a causal relation between the two by exploiting the quasi-random variation of floods in different districts and periods, the analysis demonstrates that floods have a significant positive effect on the probability of anemia through two possible transmission mechanisms. The first is a significant effect on inflammation, probably related to water borne diseases carried by unsafe drinking water, and the second is a significant negative effect on retinol concentrations. Because the effect of floods on anemia remains significant even after we control for anemia's most common causes, we argue that the condition may also be affected by elevated levels of psychological stress.
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PMID:The effect of floods on anemia among reproductive age women in Afghanistan. 2942 19

A 1-year-old female toddler who was under a great amount of psychological stress presented with acute hematemesis. She had no significant medical history; she displayed lethargy and was anemic. Although blood transfusion and famotidine were administered for upper gastrointestinal bleeding (UGIB), the anemia did not improve. Thus, early endoscopy was performed under general anesthesia, revealing a gastric ulcer with exposed vessels in the supra-angular region. Cauterization via bipolar hemostatic forceps was performed on the exposed vessels, and the bleeding was controlled successfully. We diagnosed the patient with hemorrhagic stress-induced gastric ulcer due to psychological stress. Three months later, endoscopy revealed that the gastric ulcer had healed.
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PMID:Hemorrhagic Stress-induced Gastric Ulcer in a Healthy Toddler. 2978 Jan 41


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