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Query: UMLS:C0002871 (anemia)
 52,094 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Chronic renal disease is an important clinical problem in dogs. Until recently, diffuse renal fibrosis with chronic renal failure has been attributed mainly to chronic interstitial nephritis, itself considered to be the end stage of acute leptospiral nephritis. A clinical and morphological analysis of eight cases of chronic glomerulonephritis is described and a comparison made with eight dogs suffering from severe chronic interstitial nephritis. Clinically and biochemically, the two diseases were virtually indistinguishable, both resulting in uraemia. A possible distinguishing feature of chronic interstitial nephritis was the anaemia which was absent from chronic glomerulonephritis cases. Morphologically, the two diseases appeared to be distinguishable on three grounds; the pattern and severity of fibrosis, the degree of fibrin deposition and the immunofluorescence findings.
Vet Rec 1976 Apr 10
PMID:Chronic renal failure in dogs: a comparative clinical and morphological study of chronic glomerulonephritis and chronic interstitial nephritis. 127 39

Five horses with squamous cell carcinoma of the stomach are described. The clinical findings included anorexia, weight loss, abdominal distension, abnormal chewing and swallowing behaviour and abdominal masses palpable per rectum in four cases. Haematological studies revealed a normocytic anaemia in three horses, and neutrophilia and hypoalbuminaemia in two. Analysis of peritoneal fluid revealed abnormal effusions in all five horses and neoplastic cells were identified in three of them. The tumours originated in the cardia and metastases were present in all the horses. Three of them had many small nodules covering the entire peritoneum.
Vet Rec 1992 Aug 22
PMID:Squamous cell carcinoma of the equine stomach: a report of five cases. 141 32

The deaths on nine farms of lambs which had been fed cow colostrum as a substitute for ewe colostrum were investigated. Of 105 lambs which received cow colostrum, 65 (61.9 per cent) showed clinical signs of anaemia and 42 (40 per cent) died. The signs of anaemia usually appeared when the lambs were between eight and 12 days old. The most significant post mortem finding was the appearance of the bone marrow which was cream or grey rather than the normal bright red. The types of treatment which were given are summarised. Whey from samples of the colostrum fed to the lambs was tested for its effect on sheep red blood cells. Haemolysis or agglutination of the red cells occurred with some, though not all, of the samples which caused anaemia.
Vet Rec 1992 Sep 05
PMID:Farm investigations of anaemia in lambs caused by feeding cow colostrum. 144 Nov 6

In 65 natural cases of feline infectious peritonitis (FIP) the common clinicopathological changes included lymphopenia (77 per cent), neutrophilia (45 per cent), anaemia (37 per cent), hyperproteinaemia (39 per cent) and hyperglobulinaemia (39 per cent). There was no difference in the frequency of these abnormalities between the 38 cases of effusive disease and the 27 cases of non-effusive disease. The most consistent changes shown by serum protein electrophoresis were increases in alpha 2- and gamma-globulins. The protein content of the effusions ranged from 39 to 98 g/litre with the globulins comprising 50 to 82 per cent. Coronavirus serology showed a wide variation in antibody titres (0 to 2560) with 320 the modal titre. The diagnostic value of this information was evaluated by comparing it with data from 65 cats in which FIP was considered as a differential diagnosis, but another disease was diagnosed. None of the laboratory tests, including coronavirus serology, had good sensitivity and specificity for the diagnosis of the disease. The presence of multiple abnormalities compatible with the disease increased the specificity but decreased the sensitivity of the diagnosis.
Vet Rec 1991 Sep 07
PMID:Feline infectious peritonitis: a review of clinicopathological changes in 65 cases, and a critical assessment of their diagnostic value. 194 15

The clinical signs and changes in blood and rumen fluid, and the results of therapy are described in 35 cows suffering from bleeding abomasal ulcer. The most important pathological findings were moderate to severe anaemia with pale mucous membranes and tachycardia, dark coloured to black faeces, a disturbed general condition and anorexia. Two of the cows were slaughtered immediately. The others were treated by the transfusion of several litres of blood and the intravenous administration of a solution containing sodium chloride and glucose and other drugs such as calcium solution, vitamin K, vitamin C and metoclopramide. Two animals died in spite of the treatment and three had to be slaughtered because of the deterioration in their condition. The other 28 cows recovered within a few days and their general condition, appetite and defecation returned to normal.
Vet Rec 1991 Sep 28
PMID:Bleeding abomasal ulcers in dairy cows. 196 99

A comparison was made of the serum neutralisation, immunofluorescent antibody and immunoperoxidase tests for the detection of antibodies to chicken anaemia agent. Serum samples from groups of chicks with and without maternally derived antibody to the agent were tested and the response of chicks after inoculation with the agent was also measured. The serum neutralisation test was reliable and sensitive, but expensive and could take up to three weeks to obtain a result. The immunofluorescent antibody test was cheaper and required only one day to obtain a result, but it was not as sensitive in detecting low levels of antibody to the chicken anaemia agent. The immunoperoxidase test was also cheaper but took two days to obtain a result and required one more manipulation than the immunofluorescence test. It was comparable to the serum neutralisation test in its ability to detect low levels of antibody.
Vet Rec 1991 Mar 30
PMID:A comparison of serum neutralisation, immunofluorescence and immunoperoxidase tests for the detection of antibodies to chicken anaemia agent. 203 29

Two groups of six lambs were infected either with an anthelmintic-susceptible strain of Haemonchus contortus or with a strain resistant to benzimidazoles, ivermectin and salicylanilides. The pathogenicity of the two strains of parasite was compared by monitoring the development of anaemia, changes in plasma proteins and abomasal damage in the two groups of lambs. There were no significant differences between the groups, suggesting that the development of resistance to several anthelmintics did not correlate with an increase in the pathogenicity of the parasites. Furthermore, the establishment rates and egg production of the susceptible and resistant parasites were similar. However, fewer of the eggs of the resistant parasites survived and developed at a variety of temperatures.
Vet Rec 1991 Apr 13
PMID:Effect of development of resistance to benzimidazoles, salicylanilides and ivermectin on the pathogenicity and survival of Haemonchus contortus. 206 34

Autoimmune haemolytic anaemia was diagnosed in eight horses on the basis of a positive Coomb's test. The disease was considered to be idiopathic in three cases and secondary to another condition in five. The clinical signs included dullness and depression, pyrexia, jaundice and haemoglobinuria. In addition to anaemia, haematological evaluation commonly revealed auto-agglutination of red cells and anisocytosis; reticulocytosis and an increased mean corpuscular volume were less commonly observed. Four horses were successfully treated with dexamethasone, but the other four were destroyed or died because of the underlying disease.
Vet Rec 1990 Jan 20
PMID:Autoimmune haemolytic anaemia in eight horses. 230 Nov 27

Outbreaks of clinical chicken anaemia in four broiler chicken flocks affected chicks which were all the progeny of the same parent flock. Three of the flocks were reared on farms in the south-east of England and in these flocks clinical disease did not occur in other chicks of the same age. The fourth flock was reared in a positive-pressure isolator and clinical disease appeared at 10 days of age. Chicken anaemia agent was isolated from three of the flocks. The clinical signs, post mortem lesions and histopathological changes were similar to those reported in outbreaks of the disease in other countries. The parent flock seroconverted to chicken anaemia agent, as determined by fluorescent antibody tests, during the course of the outbreaks.
Vet Rec 1989 Mar 04
PMID:An outbreak of disease due to chicken anaemia agent in broiler chickens in England. 249 96

A representative sample of the pet cat population of the United Kingdom was surveyed. Blood samples from 1204 sick and 1007 healthy cats of known breed, age and sex were tested for antibodies to feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV). The prevalence of FIV was 19 per cent in sick cats and 6 per cent in healthy cats, and the prevalence of FeLV was 18 per cent in sick cats and 5 per cent in healthy cats; both infections were more common in domestic cats than in pedigree cats. Feline immunodeficiency virus was more prevalent in older cats but FeLV was more prevalent in younger cats. There was no difference between the prevalence of FeLV in male and female cats but male cats were more likely to be infected with FIV than female cats. No interaction was demonstrated between FIV and FeLV infections. Of the cats which were in contact with FIV in households with more than one cat, 21 per cent had seroconverted. The prevalence of FeLV viraemia in cats in contact with FeLV was 14 per cent. The clinical signs associated with FIV were pyrexia, gingivitis/stomatitis and respiratory signs, and with FeLV, pyrexia and anaemia. It was concluded that both viruses were significant causes of disease, and that the cats most likely to be infected with FIV were older, free-roaming male cats and for FeLV, younger, free-roaming cats.
Vet Rec 1989 Sep 09
PMID:Prevalence of feline leukaemia virus and antibodies to feline immunodeficiency virus in cats in the United Kingdom. 255 56


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