Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0002736 (amyotrophic lateral sclerosis)
19,048 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein ALS 3355 SOD1 2379 Mol 1312 TDP-43 1163 Sep 1058 superoxide dismutase 933 axonal 835 ubiquitin 675 superoxide dismutase 1 650 FUS 508 C9orf72 502 Cu/Zn superoxide dismutase 488 SOD 408 FTD 375 endoplasmic reticulum 372 DNA-binding protein 356 prion 337 MLR 303 proteasome 290 fused 283 more...

Disease amyotrophic lateral sclerosis 19048 Alzheimer's disease 2841 Parkinson's disease 2096 dementia 2015 motor neuron disease 1144 Huntington's disease 1119 multiple sclerosis 841 muscular atrophy 606 stroke 554 FUS 508 parkinsonism 445 cancer 355 respiratory failure 313 sarcoma 306 neurological disease 297 cognitive impairment 271 epilepsy 254 neuropathy 241 depression 231 dysphagia 206 more...

Symptom weakness 842 ataxia 189 pain 183 dysarthria 161 spasticity 146 fasciculation 133 fatigue 120 tremor 97 dyspnea 80 cough 66 seizures 59 paresis 55 anesthesia 49 apathy 42 dystonia 37 functional recovery 34 paraparesis 33 cerebellar ataxia 33 asthenia 33 collapse 30 more...

Drug CSF 172 lysine 65 vitamin E 42 ROS 38 p75 32 Frontal 28 Parkin 26 Parkin 26 ascorbate 24 caffeine 17 Ranitidine 17 NADH 14 Asn 14 MRC 14 ACT 14 DM1 14 ROC 13 ADM 13 Rilutek 12 Vitamin E 11 more...

Enzyme superoxide dismutase 1250 proteasome 291 mitogen-activated protein kinase 121 protein kinase 120 caspase-3 112 ERK 77 IKK 67 choline acetyltransferase 65 ATPase 58 ACS 54 catalase 50 Alternating 46 peroxidase 44 acetylcholinesterase 39 lactate dehydrogenase 38 complex I 37 creatine kinase 37 protein kinase C 37 calcineurin 36 glutathione peroxidase 36 more...

Compound Dec 1298 DNA 836 glutamate 836 Clin 634 calcium 557 oxygen 555 copper 347 alanine 295 water 266 zinc 262 Riluzole 208 hydrogen 199 TAR 199 ATP 187 TDP 185 iron 180 sodium 177 arginine 172 nitric oxide 163 AMPA 151 more...

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