Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0002736 (
amyotrophic lateral sclerosis
)
19,048
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Autonomic fibres are generally regarded as being spared in
amyotrophic lateral sclerosis
. Anatomical studies have cast some doubt upon this hypothesis. The present study describes the pupillary responses to tyramine, a norepinephrine releaser, and to phenylephrine, a directly acting
sympathomimetic
, in 11 patients with
ALS
and matched controls. Patients and controls showed a similar sensitivity to
sympathomimetic
agents, and our results lend some support to the hypothesis that sympathetic functions are not involved in
ALS
.
...
PMID:Sympathetic iris function in amyotrophic lateral sclerosis. 358 28