Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0002736 (
amyotrophic lateral sclerosis
)
19,048
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Benzobicyclon has shown varying results in controlling weedy rice, including those with imidazolinone (IMI) resistance. Tolerance to benzobicyclon in cultivated
japonica
rice, but not
indica
or
aus
-like cultivars, is conferred by a fully functional
HPPD Inhibitor Sensitive 1
(
HIS1
) gene. Herein, a diagnostic Kompetitive Allele Specific PCR (KASP) assay was developed to predict the
HIS1
genotype of weedy rice plants from 37 accessions and correlated to their response to benzobicyclon in the field. Two-thirds of the 693 weedy rice plants screened were tolerant to benzobicyclon (371 g ai ha
-1
, SC formulation) at 30 days after treatment (DAT). Thirty-four percent of plants were homozygous for the
HIS1
allele and 98% of these plants exhibited field tolerance. However, the
his1
genotype did not always correlate with field data. Only 52% of
his1
plants were considered sensitive, indicating that the single nucleotide polymorphisms (SNPs) chosen in the KASP assay are not a reliable tool in predicting
his1
homozygous plants. In an additional experiment, 86% of the 344 plants with at least one copy of the
ALS
S653N
trait harbored a
HIS1
allele, suggesting fields infested with IMI herbicide-resistant weedy rice are unlikely to be controlled with benzobicyclon.
...
PMID:Presence of the
HPPD Inhibitor Sensitive 1
Gene and ALS
S653N
Mutation in Weedy
Oryza sativa
Sensitive to Benzobicyclon. 3320 9
