Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0002453 (
amenorrhea
)
6,245
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
prolactin
722
Sep
420
FSH
387
She
263
insulin
216
LHRH
197
follicle-stimulating hormone
191
PRL
147
chorionic gonadotropin
125
growth hormone
107
leptin
97
ACTH
96
Prolactin
89
TRH
83
MRI
72
beta-endorphin
52
HCG
45
hemoglobin
45
Mol
38
progesterone receptor
37
Leptin
35
sex hormone-binding globulin
33
thyroid hormone
33
Pol
33
estrogen receptor
33
aromatase
28
panhypopituitarism
26
thyrotropin-releasing hormone
25
JAMA
24
HDL
24
NET
24
alkaline phosphatase
23
insulin-like growth factor
21
oxytocin
20
reserved
20
BMD
20
osteocalcin
18
adrenocorticotropic hormone
18
IVF
18
collagen
17
sex hormone binding globulin
17
thyroid stimulating hormone
17
ghrelin
16
renin
16
CRH
15
hormone receptor
15
IGF-1
14
ferritin
13
nodal
13
vasopressin
12
Leydig cell
12
gonadotropin deficiency
12
kisspeptin
11
cytokine
11
delta 4
11
spermatozoa
11
IGF-I
11
FSH receptor
11
glycoprotein
10
CD4
10
calcitonin
10
somatostatin
10
HLA
10
Mal
10
alpha-fetoprotein
10
oestrogen receptor
10
AMH
9
neuropeptide Y
9
vimentin
9
Growth hormone
9
Y chromosome
9
FMR1
9
chronic renal failure
9
polypeptide
9
placental lactogen
9
IgA
8
21-hydroxylase
8
DHEAS
8
X-linked
8
GHRH
8
more...
Disease
amenorrhea
6245
galactorrhea
577
infertility
576
hyperprolactinemia
523
galactorrhea
470
abortion
353
tumor
338
osteoporosis
301
anorexia nervosa
299
secondary amenorrhea
280
uterus
260
polycystic ovary syndrome
257
cancer
225
anovulation
209
breast cancer
209
ectopic pregnancy
177
hypertension
158
obesity
156
depression
151
hypogonadism
150
diabetes
148
pituitary adenoma
126
hypothyroidism
125
endometriosis
125
premature ovarian failure
122
acne
120
adenoma
119
primary amenorrhea
106
pituitary tumor
105
hyperandrogenism
105
eating disorder
91
anemia
80
malnutrition
80
prolactinoma
76
hypomenorrhea
69
acromegaly
67
pelvic inflammatory disease
67
hypopituitarism
65
hypogonadotropic hypogonadism
63
endometrial hyperplasia
63
Turner syndrome
59
Cushing's syndrome
58
endometrial cancer
58
systemic lupus erythematosus
56
Pituitary
54
vagina
54
impotence
54
diabetes insipidus
53
cardiovascular disease
53
carcinoma
51
Ovary
51
gonadal dysgenesis
47
HCG
47
ovarian dysfunction
46
ovarian cysts
45
hypoglycemia
44
leiomyoma
43
delayed puberty
42
bulimia nervosa
40
Best
39
Cushing's disease
39
HIV
38
hyperthyroidism
37
epilepsy
36
metastases
35
congenital adrenal hyperplasia
34
sexual dysfunction
34
premature menopause
34
hydatidiform mole
33
preeclampsia
33
tuberculosis
33
hypercortisolism
32
premenstrual syndrome
32
lupus
32
tubal pregnancy
31
precocious puberty
31
gynecomastia
31
psychosis
31
migraine
31
SEM
30
more...
Symptom
headache
265
pain
231
abdominal pain
161
nausea
151
vomiting
107
irregular bleeding
82
diarrhea
72
anesthesia
65
pelvic pain
64
anorexia
59
fatigue
52
masculinization
49
hot flushes
49
dizziness
45
weakness
36
menopausal symptoms
35
discomfort
30
discomfort
30
hot flashes
27
starvation
27
seizures
25
overweight
25
polyuria
25
nausea and vomiting
23
analgesia
21
mastalgia
19
polydipsia
18
Spotting
16
menometrorrhagia
15
dyspnea
14
bloating
13
asthenia
13
syncope
13
constipation
13
lethargy
12
ataxia
12
respiratory distress
12
back pain
11
insomnia
10
thinning
10
acute abdomen
10
emaciation
10
Intermenstrual bleeding
10
acute abdominal pain
9
arthralgia
8
vertigo
8
hematocolpos
8
exhaustion
8
sleepiness
8
dysuria
8
Ill
7
cachexia
7
cough
7
abdominal discomfort
6
hepatomegaly
6
splenomegaly
6
hepatosplenomegaly
6
anosmia
6
epigastric pain
5
numbness
5
flushing
5
chest pain
5
dry skin
5
Cushingoid
5
leg pain
5
peri-menopausal
5
muscle cramps
5
hypothermia
5
pallor
5
hoarseness
5
Cushingoid
5
stigma
4
tremor
4
giddiness
4
giddiness
4
hemiplegia
4
agitation
4
abdominal cramps
4
chills
4
spasm
4
more...
Drug
MAP
121
Norplant
110
Norplant
80
EE2
70
Depo-Provera
65
HCG
45
ENT
45
Levonorgestrel
36
Parlodel
26
Clomiphene citrate
23
Dermatol
17
CTX
13
Parlodel
13
Triad
10
Triad
10
Growth hormone
9
Estrogens
9
Luteinizing
9
Zoladex
8
Zoladex
8
Growth hormone
8
Dakar
7
caffeine
7
Sulprostone
6
CSF
6
lactose
6
Premarin
6
Sulpiride
5
Implanon
5
Misoprostol
5
PTH
5
lysine
5
ascorbate
4
Prednisone
4
Ovulen
4
Metreleptin
4
Asoprisnil
4
DMAP
3
Nephron
3
Lupron
3
Lergotrile
3
Dienogest
3
Raloxifene
3
CTX
3
Gel
3
CTX
3
Cardiovasc
3
Leaf
3
Syntocinon
3
Tacrolimus
3
Gestrinone
3
Encore
3
Colombo
2
DHT
2
Gestodene
2
Serum gonadotrophin
2
Triptorelin
2
Fennel
2
Drospirenone
2
TAC
2
DHT
2
ICI
2
Tibolone
2
Epostane
2
Nephron
2
AZT
2
Gemeprost
2
CCL
2
AZT
2
Glycyrrhiza
2
DPA
2
Quingestanol acetate
2
ampicillin
2
Spectrum
2
IFN-beta
2
Vitamin B
2
Ferrous sulfate
1
Albumin
1
Mifepriston
1
Angiotensin II
1
more...
Enzyme
ERK
32
alkaline phosphatase
23
renin
16
focal adhesion kinase
8
21-hydroxylase
8
ADH
7
alcohol dehydrogenase
7
catalase
6
creatine kinase
6
ceruloplasmin
5
mitogen-activated protein kinase
4
acid phosphatase
3
protein kinase
3
thyroid peroxidase
3
lactate dehydrogenase
3
ACE
3
BMT
2
MAP
2
alanine aminotransferase
2
AMP-activated protein kinase
2
TGT
2
peroxidase
2
AMPK
2
GAS
2
tissue plasminogen activator
2
transglutaminase
2
adenylate cyclase
2
prostaglandin synthetase
2
acetylcholinesterase
2
luciferase
2
gamma-glutamyl transpeptidase
2
aspartate aminotransferase
2
thromboplastin
2
cytochrome oxidase
2
AMPK
2
proteasome
2
PRA
2
cholinesterase
2
TAT
1
CD10
1
AST
1
reverse transcriptase
1
HSD
1
alpha-L-fucosidase
1
alpha-L-fucosidase
1
11beta-hydroxysteroid dehydrogenase
1
complex I
1
NPL
1
monoamine oxidase
1
lactic acid dehydrogenase
1
succinate dehydrogenase
1
elastase
1
lipoprotein lipase
1
carboxylesterase
1
lactic acid dehydrogenase
1
aldolase
1
thrombin
1
CGT
1
ATPase
1
lactic acid dehydrogenase
1
tryptophan hydroxylase
1
caspase-1
1
alpha-L-fucosidase
1
DCF
1
PAT
1
LMT
1
esterase D
1
collagenase
1
Lod
1
lipase
1
NOS
1
cdc2
1
5'-nucleotidase
1
superoxide dismutase
1
beta-glucuronidase
1
hyaluronidase
1
CDR
1
PRE
1
TSR
1
hyaluronidase
1
more...
Compound
Clin
621
Dec
463
acetate
217
Estrogen
149
calcium
129
glucose
98
ACTH
95
MAP
89
TSH
88
TRH
84
copper
75
Progesterone
52
sulfate
51
Bromocriptine
50
iron
47
vitamin D
46
Estradiol
42
DNA
38
RU-486
37
water
35
Estrogen
35
creatinine
26
Insulin
25
DHA
24
Cortisol
23
Clomiphene citrate
22
DSM
22
Tamoxifen
21
Tamoxifen
21
aldosterone
20
BMD
20
6-12
20
sodium
20
zinc
18
Primatol
17
Primatol
17
Primatol
17
Clomiphene
16
Testosterone
16
Thyroid
16
Testosterone
16
Danazol
16
nitrogen
15
oxygen
15
Pac
14
iodine
13
CTX
13
phosphate
12
urea
11
phosphorus
11
nitric oxide
11
ethanol
11
PGE2
11
MPA
10
salt
10
Dopamine
10
MPA
10
diacetate
10
MPA
10
17-OHP
10
PEG
9
prostaglandin E1
9
L-DOPA
9
NEE
9
Naloxone
9
Isoproterenol
9
Androgen
9
Premarin
9
Norethisterone
9
Levonorgestrel
8
Clomid
8
Cardiol
8
Cabergoline
7
caffeine
7
alcohol dehydrogenase
7
Adrenal
7
potassium
7
PID
6
Risperidone
6
Methotrexate
6
more...