Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0002453 (amenorrhea)
6,245 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
prolactin 722
Sep 420
FSH 387
She 263
insulin 216
LHRH 197
follicle-stimulating hormone 191
PRL 147
chorionic gonadotropin 125
growth hormone 107
leptin 97
ACTH 96
Prolactin 89
TRH 83
MRI 72
beta-endorphin 52
HCG 45
hemoglobin 45
Mol 38
progesterone receptor 37
Leptin 35
sex hormone-binding globulin 33
thyroid hormone 33
Pol 33
estrogen receptor 33
aromatase 28
panhypopituitarism 26
thyrotropin-releasing hormone 25
JAMA 24
HDL 24
NET 24
alkaline phosphatase 23
insulin-like growth factor 21
oxytocin 20
reserved 20
BMD 20
osteocalcin 18
adrenocorticotropic hormone 18
IVF 18
collagen 17
sex hormone binding globulin 17
thyroid stimulating hormone 17
ghrelin 16
renin 16
CRH 15
hormone receptor 15
IGF-1 14
ferritin 13
nodal 13
vasopressin 12
Leydig cell 12
gonadotropin deficiency 12
kisspeptin 11
cytokine 11
delta 4 11
spermatozoa 11
IGF-I 11
FSH receptor 11
glycoprotein 10
CD4 10
calcitonin 10
somatostatin 10
HLA 10
Mal 10
alpha-fetoprotein 10
oestrogen receptor 10
AMH 9
neuropeptide Y 9
vimentin 9
Growth hormone 9
Y chromosome 9
FMR1 9
chronic renal failure 9
polypeptide 9
placental lactogen 9
IgA 8
21-hydroxylase 8
DHEAS 8
X-linked 8
GHRH 8
more...
Disease
amenorrhea 6245
galactorrhea 577
infertility 576
hyperprolactinemia 523
galactorrhea 470
abortion 353
tumor 338
osteoporosis 301
anorexia nervosa 299
secondary amenorrhea 280
uterus 260
polycystic ovary syndrome 257
cancer 225
anovulation 209
breast cancer 209
ectopic pregnancy 177
hypertension 158
obesity 156
depression 151
hypogonadism 150
diabetes 148
pituitary adenoma 126
hypothyroidism 125
endometriosis 125
premature ovarian failure 122
acne 120
adenoma 119
primary amenorrhea 106
pituitary tumor 105
hyperandrogenism 105
eating disorder 91
anemia 80
malnutrition 80
prolactinoma 76
hypomenorrhea 69
acromegaly 67
pelvic inflammatory disease 67
hypopituitarism 65
hypogonadotropic hypogonadism 63
endometrial hyperplasia 63
Turner syndrome 59
Cushing's syndrome 58
endometrial cancer 58
systemic lupus erythematosus 56
Pituitary 54
vagina 54
impotence 54
diabetes insipidus 53
cardiovascular disease 53
carcinoma 51
Ovary 51
gonadal dysgenesis 47
HCG 47
ovarian dysfunction 46
ovarian cysts 45
hypoglycemia 44
leiomyoma 43
delayed puberty 42
bulimia nervosa 40
Best 39
Cushing's disease 39
HIV 38
hyperthyroidism 37
epilepsy 36
metastases 35
congenital adrenal hyperplasia 34
sexual dysfunction 34
premature menopause 34
hydatidiform mole 33
preeclampsia 33
tuberculosis 33
hypercortisolism 32
premenstrual syndrome 32
lupus 32
tubal pregnancy 31
precocious puberty 31
gynecomastia 31
psychosis 31
migraine 31
SEM 30
more...
Symptom
headache 265
pain 231
abdominal pain 161
nausea 151
vomiting 107
irregular bleeding 82
diarrhea 72
anesthesia 65
pelvic pain 64
anorexia 59
fatigue 52
masculinization 49
hot flushes 49
dizziness 45
weakness 36
menopausal symptoms 35
discomfort 30
discomfort 30
hot flashes 27
starvation 27
seizures 25
overweight 25
polyuria 25
nausea and vomiting 23
analgesia 21
mastalgia 19
polydipsia 18
Spotting 16
menometrorrhagia 15
dyspnea 14
bloating 13
asthenia 13
syncope 13
constipation 13
lethargy 12
ataxia 12
respiratory distress 12
back pain 11
insomnia 10
thinning 10
acute abdomen 10
emaciation 10
Intermenstrual bleeding 10
acute abdominal pain 9
arthralgia 8
vertigo 8
hematocolpos 8
exhaustion 8
sleepiness 8
dysuria 8
Ill 7
cachexia 7
cough 7
abdominal discomfort 6
hepatomegaly 6
splenomegaly 6
hepatosplenomegaly 6
anosmia 6
epigastric pain 5
numbness 5
flushing 5
chest pain 5
dry skin 5
Cushingoid 5
leg pain 5
peri-menopausal 5
muscle cramps 5
hypothermia 5
pallor 5
hoarseness 5
Cushingoid 5
stigma 4
tremor 4
giddiness 4
giddiness 4
hemiplegia 4
agitation 4
abdominal cramps 4
chills 4
spasm 4
more...
Drug
MAP 121
Norplant 110
Norplant 80
EE2 70
Depo-Provera 65
HCG 45
ENT 45
Levonorgestrel 36
Parlodel 26
Clomiphene citrate 23
Dermatol 17
CTX 13
Parlodel 13
Triad 10
Triad 10
Growth hormone 9
Estrogens 9
Luteinizing 9
Zoladex 8
Zoladex 8
Growth hormone 8
Dakar 7
caffeine 7
Sulprostone 6
CSF 6
lactose 6
Premarin 6
Sulpiride 5
Implanon 5
Misoprostol 5
PTH 5
lysine 5
ascorbate 4
Prednisone 4
Ovulen 4
Metreleptin 4
Asoprisnil 4
DMAP 3
Nephron 3
Lupron 3
Lergotrile 3
Dienogest 3
Raloxifene 3
CTX 3
Gel 3
CTX 3
Cardiovasc 3
Leaf 3
Syntocinon 3
Tacrolimus 3
Gestrinone 3
Encore 3
Colombo 2
DHT 2
Gestodene 2
Serum gonadotrophin 2
Triptorelin 2
Fennel 2
Drospirenone 2
TAC 2
DHT 2
ICI 2
Tibolone 2
Epostane 2
Nephron 2
AZT 2
Gemeprost 2
CCL 2
AZT 2
Glycyrrhiza 2
DPA 2
Quingestanol acetate 2
ampicillin 2
Spectrum 2
IFN-beta 2
Vitamin B 2
Ferrous sulfate 1
Albumin 1
Mifepriston 1
Angiotensin II 1
more...
Enzyme
ERK 32
alkaline phosphatase 23
renin 16
focal adhesion kinase 8
21-hydroxylase 8
ADH 7
alcohol dehydrogenase 7
catalase 6
creatine kinase 6
ceruloplasmin 5
mitogen-activated protein kinase 4
acid phosphatase 3
protein kinase 3
thyroid peroxidase 3
lactate dehydrogenase 3
ACE 3
BMT 2
MAP 2
alanine aminotransferase 2
AMP-activated protein kinase 2
TGT 2
peroxidase 2
AMPK 2
GAS 2
tissue plasminogen activator 2
transglutaminase 2
adenylate cyclase 2
prostaglandin synthetase 2
acetylcholinesterase 2
luciferase 2
gamma-glutamyl transpeptidase 2
aspartate aminotransferase 2
thromboplastin 2
cytochrome oxidase 2
AMPK 2
proteasome 2
PRA 2
cholinesterase 2
TAT 1
CD10 1
AST 1
reverse transcriptase 1
HSD 1
alpha-L-fucosidase 1
alpha-L-fucosidase 1
11beta-hydroxysteroid dehydrogenase 1
complex I 1
NPL 1
monoamine oxidase 1
lactic acid dehydrogenase 1
succinate dehydrogenase 1
elastase 1
lipoprotein lipase 1
carboxylesterase 1
lactic acid dehydrogenase 1
aldolase 1
thrombin 1
CGT 1
ATPase 1
lactic acid dehydrogenase 1
tryptophan hydroxylase 1
caspase-1 1
alpha-L-fucosidase 1
DCF 1
PAT 1
LMT 1
esterase D 1
collagenase 1
Lod 1
lipase 1
NOS 1
cdc2 1
5'-nucleotidase 1
superoxide dismutase 1
beta-glucuronidase 1
hyaluronidase 1
CDR 1
PRE 1
TSR 1
hyaluronidase 1
more...
Compound
Clin 621
Dec 463
acetate 217
Estrogen 149
calcium 129
glucose 98
ACTH 95
MAP 89
TSH 88
TRH 84
copper 75
Progesterone 52
sulfate 51
Bromocriptine 50
iron 47
vitamin D 46
Estradiol 42
DNA 38
RU-486 37
water 35
Estrogen 35
creatinine 26
Insulin 25
DHA 24
Cortisol 23
Clomiphene citrate 22
DSM 22
Tamoxifen 21
Tamoxifen 21
aldosterone 20
BMD 20
6-12 20
sodium 20
zinc 18
Primatol 17
Primatol 17
Primatol 17
Clomiphene 16
Testosterone 16
Thyroid 16
Testosterone 16
Danazol 16
nitrogen 15
oxygen 15
Pac 14
iodine 13
CTX 13
phosphate 12
urea 11
phosphorus 11
nitric oxide 11
ethanol 11
PGE2 11
MPA 10
salt 10
Dopamine 10
MPA 10
diacetate 10
MPA 10
17-OHP 10
PEG 9
prostaglandin E1 9
L-DOPA 9
NEE 9
Naloxone 9
Isoproterenol 9
Androgen 9
Premarin 9
Norethisterone 9
Levonorgestrel 8
Clomid 8
Cardiol 8
Cabergoline 7
caffeine 7
alcohol dehydrogenase 7
Adrenal 7
potassium 7
PID 6
Risperidone 6
Methotrexate 6
more...