Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0002453 (amenorrhea)
 6,245 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
prolactin 722
Sep 420
FSH 387
She 263
insulin 216
LHRH 197
follicle-stimulating hormone 191
PRL 147
chorionic gonadotropin 125
growth hormone 107
leptin 97
ACTH 96
Prolactin 89
TRH 83
MRI 72
beta-endorphin 52
hemoglobin 45
HCG 45
Mol 38
progesterone receptor 37
Leptin 35
sex hormone-binding globulin 33
thyroid hormone 33
Pol 33
estrogen receptor 33
aromatase 28
panhypopituitarism 26
thyrotropin-releasing hormone 25
NET 24
JAMA 24
HDL 24
alkaline phosphatase 23
insulin-like growth factor 21
reserved 20
oxytocin 20
BMD 20
osteocalcin 18
IVF 18
adrenocorticotropic hormone 18
thyroid stimulating hormone 17
collagen 17
sex hormone binding globulin 17
ghrelin 16
renin 16
CRH 15
hormone receptor 15
IGF-1 14
nodal 13
ferritin 13
vasopressin 12
Leydig cell 12
gonadotropin deficiency 12
delta 4 11
spermatozoa 11
kisspeptin 11
FSH receptor 11
IGF-I 11
cytokine 11
Mal 10
HLA 10
glycoprotein 10
alpha-fetoprotein 10
CD4 10
somatostatin 10
calcitonin 10
oestrogen receptor 10
polypeptide 9
Growth hormone 9
AMH 9
neuropeptide Y 9
vimentin 9
placental lactogen 9
Y chromosome 9
FMR1 9
chronic renal failure 9
X-linked 8
GHRH 8
DHEAS 8
21-hydroxylase 8
IgA 8
hemochromatosis 8
GPR54 8
insulin receptor 8
IGFBP-1 8
insulin-like growth factor-I 8
POF 7
C-reactive protein 7
kit 7
hPRL 7
ADH 7
Dakar 7
IGFBP-3 7
cryptic 7
Hop 7
insulin-like growth factor 1 7
GnRH receptor 7
insulin-like growth factor I 7
type I collagen 7
transferrin 7
interferon 7
cytokeratin 7
FSHR 6
CSF 6
HER2 6
opioid receptor 6
adiponectin 6
peptide YY 6
parathyroid hormone 6
lymphoid 6
PID 6
Ki-67 6
androgen receptor 6
glial fibrillary acidic protein 6
ceruloplasmin 5
synaptophysin 5
dopamine D2 receptor 5
IGF binding 5
IL-6 5
Aromatase 5
EMA 5
San 5
fibrinogen 5
ACR 5
apolipoprotein 5
arginine vasopressin 5
antithrombin III 5
PTH 5
glucocorticoid receptor 5
Men 5
MIB 5
tap 5
axonal 5
p11 5
Mil 5
tumor necrosis factor 5
FISH 4
prothrombin 4
vascular endothelial growth factor 4
CYP21 4
creatine kinase 4
non-Hodgkin's lymphoma 4
ANOVA 4
LRF 4
CAT 4
GDF9 4
interferon-alpha 4
interleukin-6 4
microsomal 4
apolipoprotein B 4
A-I 4
bone morphogenetic protein 15 4
calretinin 4
albumin 4
CYP17 4
STH 4
p53 4
S100 4
olfactory 4
Net 4
proopiomelanocortin 4
more...
Disease
amenorrhea 6245
galactorrhea 577
infertility 576
hyperprolactinemia 523
galactorrhea 470
abortion 353
tumor 338
osteoporosis 301
anorexia nervosa 299
secondary amenorrhea 280
uterus 260
polycystic ovary syndrome 257
cancer 225
anovulation 209
breast cancer 209
ectopic pregnancy 177
hypertension 158
obesity 156
depression 151
hypogonadism 150
diabetes 148
pituitary adenoma 126
hypothyroidism 125
endometriosis 125
premature ovarian failure 122
acne 120
adenoma 119
primary amenorrhea 106
hyperandrogenism 105
pituitary tumor 105
eating disorder 91
malnutrition 80
anemia 80
prolactinoma 76
hypomenorrhea 69
acromegaly 67
pelvic inflammatory disease 67
hypopituitarism 65
hypogonadotropic hypogonadism 63
endometrial hyperplasia 63
Turner syndrome 59
Cushing's syndrome 58
endometrial cancer 58
systemic lupus erythematosus 56
impotence 54
vagina 54
Pituitary 54
diabetes insipidus 53
cardiovascular disease 53
carcinoma 51
Ovary 51
gonadal dysgenesis 47
HCG 47
ovarian dysfunction 46
ovarian cysts 45
hypoglycemia 44
leiomyoma 43
delayed puberty 42
bulimia nervosa 40
Cushing's disease 39
Best 39
HIV 38
hyperthyroidism 37
epilepsy 36
metastases 35
premature menopause 34
congenital adrenal hyperplasia 34
sexual dysfunction 34
hydatidiform mole 33
preeclampsia 33
tuberculosis 33
lupus 32
premenstrual syndrome 32
hypercortisolism 32
gynecomastia 31
precocious puberty 31
psychosis 31
migraine 31
tubal pregnancy 31
binge eating 30
SEM 30
endocrine disorder 29
Sheehan's syndrome 28
gestational trophoblastic disease 27
panhypopituitarism 27
mental illness 26
Hodgkin's disease 26
azoospermia 26
adrenal insufficiency 26
stroke 25
schizophrenia 25
vaginal discharge 24
incontinence 23
hyperinsulinemia 23
uterine leiomyoma 23
type 2 diabetes 22
choriocarcinoma 22
lupus nephritis 22
prematurity 21
Asherman's syndrome 21
West 21
adenomyosis 21
AIDS 21
cirrhosis 20
oligospermia 20
thrombocytopenia 20
goiter 20
endometritis 20
fallopian tube 20
multiple sclerosis 20
BMD 20
myoma 19
hydrocephalus 19
liver disease 19
renal disease 19
proteinuria 19
dysplasia 19
metabolic syndrome 18
psychological stress 18
celiac disease 18
IVF 18
heart failure 17
cervical cancer 17
polymenorrhea 17
Lupus 17
pruritus 17
lymphoma 16
ovarian cancer 16
craniopharyngioma 16
sarcoidosis 16
autoimmune disease 16
cold 16
immunodeficiency 15
Hypothalamic amenorrhea 15
adenocarcinoma 14
glucose intolerance 14
Female Athlete Triad 14
type 1 diabetes 14
vaginal atrophy 14
rare disease 14
leukemia 14
21-hydroxylase deficiency 14
cystic fibrosis 14
lupus 14
cystitis 14
malabsorption 14
trophoblastic tumor 14
hematometra 14
mental retardation 13
heart disease 13
STD 13
residual disease 13
urinary tract infection 13
external genitalia 13
chronic renal failure 13
rheumatoid arthritis 13
Syndrome 13
hyperlipidemia 13
chronic disease 13
hyperglycemia 13
more...
Symptom
headache 265
pain 231
abdominal pain 161
nausea 151
vomiting 107
irregular bleeding 82
diarrhea 72
anesthesia 65
pelvic pain 64
anorexia 59
fatigue 52
masculinization 49
hot flushes 49
dizziness 45
weakness 36
menopausal symptoms 35
discomfort 30
discomfort 30
starvation 27
hot flashes 27
polyuria 25
overweight 25
seizures 25
nausea and vomiting 23
analgesia 21
mastalgia 19
polydipsia 18
Spotting 16
menometrorrhagia 15
dyspnea 14
constipation 13
bloating 13
asthenia 13
syncope 13
ataxia 12
respiratory distress 12
lethargy 12
back pain 11
thinning 10
acute abdomen 10
Intermenstrual bleeding 10
insomnia 10
emaciation 10
acute abdominal pain 9
arthralgia 8
hematocolpos 8
sleepiness 8
vertigo 8
exhaustion 8
dysuria 8
cachexia 7
cough 7
Ill 7
splenomegaly 6
abdominal discomfort 6
hepatomegaly 6
hepatosplenomegaly 6
anosmia 6
flushing 5
numbness 5
hoarseness 5
muscle cramps 5
Cushingoid 5
peri-menopausal 5
leg pain 5
chest pain 5
pallor 5
dry skin 5
hypothermia 5
Cushingoid 5
epigastric pain 5
tremor 4
stigma 4
hemiplegia 4
chills 4
abdominal cramps 4
agitation 4
giddiness 4
spasm 4
giddiness 4
hunger 4
dysorexia 3
blurred vision 3
memory loss 3
night sweats 3
tingling 3
unable to conceive 3
intermenstrual pain 3
ophthalmoplegia 3
cerebellar ataxia 3
orthopnea 3
Welt 3
stomach pain 3
paresis 3
paresthesia 3
nipple discharge 3
hypotonia 3
spasticity 3
dystonia 3
Physical findings 2
acute stress 2
enuresis 2
sore throat 2
erythema 2
frequent urination 2
blemishes 2
acute pain 2
Breast tenderness 2
Abdominal tenderness 2
Lower abdominal pain 2
oliguria 2
ENT 2
incoordination 2
Vaginal dryness 2
neck pain 2
paraparesis 2
tenesmus 2
pedal edema 2
colic 2
dysesthesia 2
groin pain 2
reproductive problem 2
exertional dyspnea 2
leg cramps 2
urinary frequency 2
nipple discharge 2
neurological disability 2
hyperemesis gravidarum 2
cyanosis 2
angina 2
iliac fossa pain 2
cancer pain 2
consciousness disturbance 2
knee pain 2
tinnitus 2
Fatigability 1
voice change 1
torticollis 1
female puberty 1
Involuntary Movement 1
Pruritus of pregnancy 1
flank pain 1
generalized abdominal pain 1
testicular lump 1
hearing voices 1
Wind 1
collapse 1
Cramping 1
Pituitary enlargement 1
Abdominal and pelvic pain 1
hemoptysis 1
Climacteric symptoms 1
ovulatory bleeding 1
myalgia 1
chest tightness 1
Pain symptoms 1
lightheadedness 1
inanition 1
Premenstrual symptoms 1
hypocapnia 1
more...
Drug
MAP 121
Norplant 110
Norplant 80
EE2 70
Depo-Provera 65
ENT 45
HCG 45
Levonorgestrel 36
Parlodel 26
Clomiphene citrate 23
Dermatol 17
Parlodel 13
CTX 13
Triad 10
Triad 10
Luteinizing 9
Estrogens 9
Growth hormone 9
Zoladex 8
Growth hormone 8
Zoladex 8
caffeine 7
Dakar 7
Sulprostone 6
lactose 6
CSF 6
Premarin 6
Misoprostol 5
Sulpiride 5
Implanon 5
PTH 5
lysine 5
ascorbate 4
Prednisone 4
Metreleptin 4
Ovulen 4
Asoprisnil 4
Tacrolimus 3
Gel 3
Leaf 3
Lergotrile 3
CTX 3
Cardiovasc 3
Nephron 3
Raloxifene 3
Syntocinon 3
Encore 3
Lupron 3
Dienogest 3
Gestrinone 3
CTX 3
DMAP 3
ICI 2
Colombo 2
Glycyrrhiza 2
Serum gonadotrophin 2
Fennel 2
Drospirenone 2
DHT 2
Spectrum 2
DHT 2
DPA 2
ampicillin 2
Nephron 2
Epostane 2
Gemeprost 2
AZT 2
CCL 2
Tibolone 2
Quingestanol acetate 2
AZT 2
Triptorelin 2
Vitamin B 2
Gestodene 2
IFN-beta 2
TAC 2
Dexon 1
Mectizan 1
Albumin 1
Hyaluronidase 1
Collodion 1
Trimegestone 1
Mifepriston 1
Auranofin 1
Terguride 1
Glutethimide 1
Asn 1
ROS 1
Orlistat 1
Meth 1
Novantrone 1
TAT 1
DDAVP 1
Sumatran 1
Adriamycin 1
Bayer 1
VCR 1
Estriol 1
Antithrombin III 1
CTA 1
PPA 1
Dial 1
Domperidone 1
Lipiodol 1
Pegvisomant 1
Indomethacin 1
Anafranil 1
Buserelin acetate 1
EHDP 1
APM 1
Lisuride 1
Demerol 1
Trib 1
Dostinex 1
Asthma 1
Talc 1
Methergin 1
Horizon 1
Reboxetine 1
Conray 1
Monit 1
CET 1
Dexrazoxane 1
Methyldopa 1
CDP 1
AGG 1
Escitalopram 1
Ferrous sulfate 1
Android 1
DDAVP 1
Oxendolone 1
Rituximab 1
Angiotensin II 1
ROC 1
Hyaluronidase 1
Etoposide 1
Spectrum 1
Cellcept 1
Cellcept 1
Taxotere 1
Histamine 1
Gelfoam 1
Doxycycline 1
Lergotrile mesylate 1
Herceptin 1
Ortho Tri-Cyclen 1
Reserpine 1
Diurnal 1
Acyclovir 1
Vitamin E 1
Rosiglitazone 1
Ogen 1
Prednisolone 1
Enzyme
ERK 32
alkaline phosphatase 23
renin 16
focal adhesion kinase 8
21-hydroxylase 8
ADH 7
alcohol dehydrogenase 7
catalase 6
creatine kinase 6
ceruloplasmin 5
mitogen-activated protein kinase 4
acid phosphatase 3
protein kinase 3
thyroid peroxidase 3
lactate dehydrogenase 3
ACE 3
BMT 2
MAP 2
alanine aminotransferase 2
AMP-activated protein kinase 2
TGT 2
peroxidase 2
AMPK 2
GAS 2
tissue plasminogen activator 2
transglutaminase 2
adenylate cyclase 2
prostaglandin synthetase 2
acetylcholinesterase 2
luciferase 2
gamma-glutamyl transpeptidase 2
aspartate aminotransferase 2
thromboplastin 2
cytochrome oxidase 2
AMPK 2
proteasome 2
PRA 2
cholinesterase 2
TAT 1
CD10 1
AST 1
reverse transcriptase 1
HSD 1
alpha-L-fucosidase 1
alpha-L-fucosidase 1
11beta-hydroxysteroid dehydrogenase 1
complex I 1
NPL 1
monoamine oxidase 1
lactic acid dehydrogenase 1
succinate dehydrogenase 1
elastase 1
lipoprotein lipase 1
carboxylesterase 1
lactic acid dehydrogenase 1
aldolase 1
thrombin 1
CGT 1
ATPase 1
lactic acid dehydrogenase 1
tryptophan hydroxylase 1
caspase-1 1
alpha-L-fucosidase 1
DCF 1
PAT 1
LMT 1
esterase D 1
collagenase 1
Lod 1
lipase 1
NOS 1
cdc2 1
5'-nucleotidase 1
superoxide dismutase 1
beta-glucuronidase 1
hyaluronidase 1
CDR 1
PRE 1
TSR 1
hyaluronidase 1
Compound
Clin 621
Dec 463
acetate 217
Estrogen 149
calcium 129
glucose 98
ACTH 95
MAP 89
TSH 88
TRH 84
copper 75
Progesterone 52
sulfate 51
Bromocriptine 50
iron 47
vitamin D 46
Estradiol 42
DNA 38
RU-486 37
water 35
Estrogen 35
creatinine 26
Insulin 25
DHA 24
Cortisol 23
Clomiphene citrate 22
DSM 22
Tamoxifen 21
Tamoxifen 21
6-12 20
BMD 20
aldosterone 20
sodium 20
zinc 18
Primatol 17
Primatol 17
Primatol 17
Danazol 16
Clomiphene 16
Thyroid 16
Testosterone 16
Testosterone 16
nitrogen 15
oxygen 15
Pac 14
iodine 13
CTX 13
phosphate 12
phosphorus 11
ethanol 11
PGE2 11
urea 11
nitric oxide 11
MPA 10
salt 10
diacetate 10
MPA 10
MPA 10
17-OHP 10
Dopamine 10
Norethisterone 9
Naloxone 9
Androgen 9
NEE 9
L-DOPA 9
Premarin 9
prostaglandin E1 9
Isoproterenol 9
PEG 9
Cardiol 8
Clomid 8
Levonorgestrel 8
alcohol dehydrogenase 7
Cabergoline 7
caffeine 7
potassium 7
Adrenal 7
Metoclopramide 6
Risperidone 6
PID 6
Optimal 6
silver 6
Methotrexate 6
PID 6
Premarin 6
His 6
prostaglandin F2alpha 6
benzamide 5
Naltrexone 5
Cyproterone acetate 5
cAMP 5
Vitamin D 5
A 42 5
methanol 5
arginine 5
lysine 5
BMC 5
Lynestrenol 5
Hemoglobin 5
5-FU 4
Prostaglandin 4
Melatonin 4
CAT 4
tryptophan 4
Metformin 4
Metformin 4
Estrone 4
tryptophan 4
Phe 4
Mitoxantrone 4
5-HT 4
Diabetol 4
Prednisone 4
Androstenedione 4
Prostaglandin 4
glycerol 4
CAP 4
DHA 4
Mitoxantrone 4
CAT 4
Valproic acid 4
aluminum 4
CAT 4
Spironolactone 4
PGE 4
DHA 3
GABA 3
MCH 3
PMS 3
DMAP 3
Abbott 3
noradrenaline 3
A 1 3
Formal 3
tyrosine 3
bromide 3
Leuprolide 3
Rutaecarpine 3
Organon 3
tryptophan 3
CO2 3
Mycophenolate mofetil 3
methionine 3
FK506 3
PVA 3
TNF 3
fluorine 3
homocysteine 3
L-T3 3
Olanzapine 3
Prednisolone 3
A 3 3
Dexamethasone 3
Diabetol 3
Gly 3
galactose 3
Thyroxine 3
A 150 3
ATP 3
GABA 3
more...