Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0002453 (amenorrhea)
 6,245 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Progestational contraception (CMP) is rarely used. In France, its indications are not clearly defined. The prescription is justified when there is a contra-indication to estrogen use (uterus fibroids, endometrial hyperplasia, endometriosis, fibro-cystic disease of the breast). The side effects are menstruation disorders (metrorrhagias, amenorrhea), weight gain, atherogenic metabolic changes. Actually, nor-pregnane derivatives, which correctly block ovulation, do not seem to have a deleterious effect on glucide and lipid parameters. At last, it is not sure that CMP may be prescribed to a patient previously treated for a breast cancer.
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PMID:[High-dose progestational contraception: side effects]. 795 3

Peripartum cardiomyopathy (PP-CMP) or Meadows' syndrom, is a dilated cardiomyopathy which occurs during or following pregnancy. It is characterized by heart failure with a systolic left ventricle ejection fraction of less than 45%. It is rare and its pathophysiologic mechanism is poorly elucidated. From a clinical point of view, it is characterized by unespected heart failure with rapid onset of symptoms, unpredictable evolution and risk of refractory cardiogenic shock, justifying patient's management in Cardiovascular Unit. PP-CMP requires no specific treatment compared to other causes of heart failure. We here report the case of a 29-year old primip at 32 weeks of amenorrhea presenting with congestive heart failure associated with peripartum cardiomyopathy. The aim of this study was to highlight the features of this heart disease which, despite its rarity, should not be disregarded by obstetricians.
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PMID:[Peripartum cardiomyopathy]. 2963 29