Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0002395 (Alzheimer's disease)
110,584 document(s) hit in 31,850,051 MEDLINE articles (0.06 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein amyloid precursor protein 14407 Mol 6481 Sep 6177 amyloid beta 4377 APP 3391 acetylcholinesterase 3361 tau protein 3360 apolipoprotein E 2670 insulin 2156 MRI 2101 PS1 2081 BACE1 1773 APOE 1705 CA1 1562 prion 1468 DAT 1465 axonal 1441 cytokine 1235 precursor protein 1171 endoplasmic reticulum 1137 caspase-3 1116 ubiquitin 1070 ATP 987 CSF 965 brain-derived neurotrophic factor 952 presenilin 1 939 synuclein 904 NMR 880 ACS 861 butyrylcholinesterase 853 olfactory 845 glial fibrillary acidic protein 819 GSK 817 TNF 803 Apolipoprotein E 787 alpha-synuclein 755 choline acetyltransferase 747 prion protein 742 proteasome 705 tumor necrosis factor 703 superoxide dismutase 699 apolipoprotein 668 nerve growth factor 642 lipopolysaccharide 629 NMDA receptor 615 amyloid protein 608 IL-6 591 synaptophysin 559 Bcl-2 556 AChE 516 FDG 515 apoE 511 GSH 502 BACE 498 CA3 493 nicotinic acetylcholine receptor 476 PrP 476 polypeptide 475 GABA 464 chromosome 21 463 microtubule-associated protein 461 inducible nitric oxide synthase 457 neutral endopeptidase 451 MAPK 430 catalase 425 ROS 422 p53 420 p38 410 SDS 402 neurotrophin 400 threonine 398 gut 394 PSEN1 391 mTOR 384 phosphatase 381 JNK 362 membrane-bound 362 somatostatin 354 ERK 345 amylin 343 more...

Disease Alzheimer's disease 110584 dementia 22987 cognitive impairment 11246 Parkinson's disease 9103 plaque 4172 depression 3460 diabetes 3250 stroke 3153 Huntington's disease 3111 amyotrophic lateral sclerosis 2841 cancer 2838 schizophrenia 2234 multiple sclerosis 2071 memory impairment 2036 Down syndrome 1850 neuroblastoma 1740 vascular disease 1496 epilepsy 1383 amyloidosis 1349 hypertension 1223 type 2 diabetes 1130 atherosclerosis 1032 senile dementia 999 parkinsonism 988 brain atrophy 940 obesity 933 ischemia 928 Dementia with Lewy bodies 903 progressive supranuclear palsy 886 cardiovascular disease 816 Creutzfeldt-Jakob disease 668 autism 654 psychosis 639 aphasia 620 neurological disease 618 major depressive disorder 560 multi-infarct dementia 553 tumor 543 Pick's disease 531 GSH 502 encephalopathy 490 HIV 480 cerebral ischemia 459 hallucinations 445 amnesia 430 SDS 403 bipolar disorder 384 cognitive deficit 383 delusions 353 osteoporosis 343 mental illness 336 CNS diseases 333 rheumatoid arthritis 329 glaucoma 285 hypercholesterolemia 277 aggression 276 hydrocephalus 267 apraxia 266 pheochromocytoma 266 breast cancer 262 AIDS 255 heart disease 254 metabolic syndrome 251 Vascular dementia 244 arthritis 233 macular degeneration 232 CAA 231 mental retardation 229 mental retardation 223 delirium 218 confusion 218 motor neuron disease 215 hyperglycemia 212 herpes simplex 208 asthma 200 disinhibition 197 malnutrition 196 scrapie 196 encephalitis 194 infectious diseases 192 more...

Symptom memory loss 1488 seizures 681 pain 642 agitation 533 apathy 404 ataxia 271 tremor 268 thinning 224 insomnia 197 anesthesia 181 myoclonus 152 fatigue 131 collapse 116 headache 108 bradykinesia 106 diarrhea 103 weakness 97 functional recovery 97 vomiting 96 sleepiness 96 dystonia 93 nausea 89 starvation 84 forgetfulness 81 hypothermia 79 dizziness 70 overweight 69 stigma 67 anorexia 65 personality change 61 discomfort 58 cerebellar ataxia 55 exhaustion 54 discomfort 47 paraparesis 46 Depressive symptoms 46 syncope 40 tinnitus 34 nausea and vomiting 33 chorea 32 analgesia 32 anosmia 31 constipation 30 menopausal symptoms 29 dysarthria 28 spasticity 28 hypercapnia 28 cough 28 acute stress 27 visual hallucination 25 distraction 25 paresis 24 pallor 23 Behavioral symptoms 22 hyperoxia 22 lethargy 21 muscle rigidity 18 cachexia 18 HSA 18 hypotonia 17 Extrapyramidal symptoms 17 angina 17 abnormal gait 16 vertigo 16 respiratory distress 15 Psychiatric symptoms 14 hot flashes 14 ophthalmoplegia 13 acidity 13 hopelessness 13 hemiplegia 13 Ill 13 motor symptom 13 hot flushes 13 shortness of breath 12 despair 12 back pain 12 incoordination 10 fasciculation 10 ACHE 9 more...

Drug CSF 990 ROS 422 lysine 377 Donepezil 374 vitamin E 343 Spectrum 250 ascorbate 202 ENT 188 caffeine 167 p75 167 ROC 155 Frontal 148 FAD 139 MAP 112 THA 106 NADH 89 Aricept 83 Monit 82 Leaf 79 Parkin 78 Parkin 78 Scopolamine 78 Heme 70 IL-2 68 Vitamin E 67 IFN-gamma 63 Glutathione 63 Asn 59 ABC 59 Estrogens 54 Biopolymers 52 Cardiovasc 52 EPA 48 Glucagon 47 Albumin 43 Histamine 38 Gel 36 citric acid 35 Ginseng 33 Galanthamine 33 TAT 33 Nephron 32 nitroglycerin 31 Methylene blue 31 EE2 30 PCP 30 Exelon 29 ACT 29 Indomethacin 28 Dermatol 28 DMAA 26 Namenda 26 Portal 25 Exelon 25 Liraglutide 24 Vitamin B12 24 ICI 23 Reminyl 23 HCH 22 TAK 22 Spectrum 22 MRC 22 Xanthium 21 Paraffin 21 Piracetam 20 Alanine 20 Kainic acid 20 GEO 20 Angiotensin II 20 ALA 20 Nitric Oxide 19 Rosiglitazone 19 Ethanol 19 Retinoic acid 18 Bexarotene 18 Fragment 18 Taxol 18 ADM 18 Cognex 17 IL-1ra 17 more...

Enzyme acetylcholinesterase 4380 cholinesterase 2286 protein kinase 1533 mitogen-activated protein kinase 1485 DAT 1465 GSK 961 caspase-3 886 superoxide dismutase 871 ACS 861 ERK 757 choline acetyltransferase 755 proteasome 713 beta-secretase 656 protein kinase C 546 catalase 484 calcineurin 480 CD10 453 monoamine oxidase 341 glutathione peroxidase 336 insulin-degrading enzyme 273 lactate dehydrogenase 265 ATPase 255 luciferase 231 tyrosine hydroxylase 222 focal adhesion kinase 221 peroxidase 200 AMP-activated protein kinase 198 ACE 182 cathepsin D 176 trypsin 173 NADPH oxidase 160 NADPH oxidase 160 protein phosphatase 2A 157 cytochrome oxidase 154 AMPK 151 cdc2 151 CDR 147 phosphatidylinositol 3-kinase 146 P-glycoprotein 144 complex I 142 thrombin 141 phospholipase A2 134 MEK 131 renin 131 NO synthase 127 phosphodiesterase 127 alkaline phosphatase 124 caspase-1 120 CaMKII 114 glutathione S-transferase 112 AMPK 111 cathepsin B 109 phospholipase C 109 PARP 105 glutathione reductase 103 lysozyme 100 plasmin 99 ceruloplasmin 95 kinesin 94 caspase-9 93 reverse transcriptase 92 heme oxygenase 85 MAP 84 glutamine synthetase 82 NOS 82 phosphoinositide 3-kinase 81 transglutaminase 79 tissue plasminogen activator 75 glyceraldehyde-3-phosphate dehydrogenase 74 CYP46A1 73 pyruvate dehydrogenase 72 ATP synthase 69 succinate dehydrogenase 68 glyceraldehyde-3-phosphate dehydrogenase 66 chymotrypsin 63 alpha-ketoglutarate dehydrogenase 63 Thy1 63 alcohol dehydrogenase 61 caspase-8 61 RNase 60 more...

Compound Dec 6712 Clin 3625 oxygen 3478 water 3458 DNA 3210 calcium 2829 glucose 2591 glutamate 2072 DAT 1465 iron 1348 hydrogen 1230 copper 1152 nitric oxide 1077 ATP 987 zinc 967 ACS 862 ACS 861 TNF 803 sodium 798 tyrosine 791 serine 727 Neuronal 666 threonine 657 aluminum 653 cysteine 615 phosphate 611 NMDA 602 lysine 557 sulfate 548 GSH 542 GSH 542 homocysteine 524 methionine 487 alanine 474 GABA 473 GABA 466 arginine 466 His 451 silver 434 MTT 432 Congo red 417 5-HT 415 SDS 413 acetate 410 nitrogen 394 galactose 383 Cereb 383 DSM 373 cAMP 367 potassium 349 Asp 340 leucine 315 H2O2 314 salt 312 proline 299 tryptophan 298 ethanol 298 galanthamine 297 tryptophan 290 Insulin 289 Memantine 283 tryptophan 278 tryptophan 278 AMPA 275 noradrenaline 254 Phe 252 glutamine 247 Curcumin 242 ACh 240 Cu(II) 220 Cholesterol 215 Glutamate 212 bromide 210 NAD 206 iodine 194 manganese 193 Glycogen synthase 191 Melatonin 190 Estrogen 187 Estrogen 183 more...

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