Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UMLS:C0002395 (Alzheimer's disease)
110,584 document(s) hit in 31,850,051 MEDLINE articles (0.06 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein amyloid precursor protein 14407 Mol 6481 Sep 6177 amyloid beta 4377 APP 3391 acetylcholinesterase 3361 tau protein 3360 apolipoprotein E 2670 insulin 2156 MRI 2101 PS1 2081 BACE1 1773 APOE 1705 CA1 1562 prion 1468 DAT 1465 axonal 1441 cytokine 1235 precursor protein 1171 endoplasmic reticulum 1137 caspase-3 1116 ubiquitin 1070 ATP 987 CSF 965 brain-derived neurotrophic factor 952 presenilin 1 939 synuclein 904 NMR 880 ACS 861 butyrylcholinesterase 853 olfactory 845 glial fibrillary acidic protein 819 GSK 817 TNF 803 Apolipoprotein E 787 alpha-synuclein 755 choline acetyltransferase 747 prion protein 742 proteasome 705 tumor necrosis factor 703 more...

Disease Alzheimer's disease 110584 dementia 22987 cognitive impairment 11246 Parkinson's disease 9103 plaque 4172 depression 3460 diabetes 3250 stroke 3153 Huntington's disease 3111 amyotrophic lateral sclerosis 2841 cancer 2838 schizophrenia 2234 multiple sclerosis 2071 memory impairment 2036 Down syndrome 1850 neuroblastoma 1740 vascular disease 1496 epilepsy 1383 amyloidosis 1349 hypertension 1223 type 2 diabetes 1130 atherosclerosis 1032 senile dementia 999 parkinsonism 988 brain atrophy 940 obesity 933 ischemia 928 Dementia with Lewy bodies 903 progressive supranuclear palsy 886 cardiovascular disease 816 Creutzfeldt-Jakob disease 668 autism 654 psychosis 639 aphasia 620 neurological disease 618 major depressive disorder 560 multi-infarct dementia 553 tumor 543 Pick's disease 531 GSH 502 more...

Symptom memory loss 1488 seizures 681 pain 642 agitation 533 apathy 404 ataxia 271 tremor 268 thinning 224 insomnia 197 anesthesia 181 myoclonus 152 fatigue 131 collapse 116 headache 108 bradykinesia 106 diarrhea 103 functional recovery 97 weakness 97 sleepiness 96 vomiting 96 dystonia 93 nausea 89 starvation 84 forgetfulness 81 hypothermia 79 dizziness 70 overweight 69 stigma 67 anorexia 65 personality change 61 discomfort 58 cerebellar ataxia 55 exhaustion 54 discomfort 47 paraparesis 46 Depressive symptoms 46 syncope 40 tinnitus 34 nausea and vomiting 33 chorea 32 more...

Drug CSF 990 ROS 422 lysine 377 Donepezil 374 vitamin E 343 Spectrum 250 ascorbate 202 ENT 188 p75 167 caffeine 167 ROC 155 Frontal 148 FAD 139 MAP 112 THA 106 NADH 89 Aricept 83 Monit 82 Leaf 79 Scopolamine 78 Parkin 78 Parkin 78 Heme 70 IL-2 68 Vitamin E 67 Glutathione 63 IFN-gamma 63 ABC 59 Asn 59 Estrogens 54 Cardiovasc 52 Biopolymers 52 EPA 48 Glucagon 47 Albumin 43 Histamine 38 Gel 36 citric acid 35 TAT 33 Galanthamine 33 more...

Enzyme acetylcholinesterase 4380 cholinesterase 2286 protein kinase 1533 mitogen-activated protein kinase 1485 DAT 1465 GSK 961 caspase-3 886 superoxide dismutase 871 ACS 861 ERK 757 choline acetyltransferase 755 proteasome 713 beta-secretase 656 protein kinase C 546 catalase 484 calcineurin 480 CD10 453 monoamine oxidase 341 glutathione peroxidase 336 insulin-degrading enzyme 273 lactate dehydrogenase 265 ATPase 255 luciferase 231 tyrosine hydroxylase 222 focal adhesion kinase 221 peroxidase 200 AMP-activated protein kinase 198 ACE 182 cathepsin D 176 trypsin 173 NADPH oxidase 160 NADPH oxidase 160 protein phosphatase 2A 157 cytochrome oxidase 154 cdc2 151 AMPK 151 CDR 147 phosphatidylinositol 3-kinase 146 P-glycoprotein 144 complex I 142 more...

Compound Dec 6712 Clin 3625 oxygen 3478 water 3458 DNA 3210 calcium 2829 glucose 2591 glutamate 2072 DAT 1465 iron 1348 hydrogen 1230 copper 1152 nitric oxide 1077 ATP 987 zinc 967 ACS 862 ACS 861 TNF 803 sodium 798 tyrosine 791 serine 727 Neuronal 666 threonine 657 aluminum 653 cysteine 615 phosphate 611 NMDA 602 lysine 557 sulfate 548 GSH 542 GSH 542 homocysteine 524 methionine 487 alanine 474 GABA 473 arginine 466 GABA 466 His 451 silver 434 MTT 432 more...

---