Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0001577 (adnexitis)
 232 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A clinical trial on efficacy and tolerance of Cefazedone, a new semisynthetic Cephalosporine-derivate, was carried out in a gynaecological clinic on 75 patients. In 38 of these cases, besides the gynaecological affection, urinary tract infections were determined microbiologically (E. coli, P. mirabilis, klebsiella or enterococci). Inflammation of the lower abdominal area was established in the remaining 37 patients (adnexitis, pelvic peritonitis, endometritis, salpingitis). The average duration of treatment was 10 to 11 days. Cefazedone was injected intravenously twice a day, the daily dose was 2 to 4 g. The clinical assessment of the treatment was very good in 28 cases, good in 43 cases, moderate in 3 patients and poor in 1 case. All initially identified pathogens were eliminated after treatment. A slight transitory diarrhea was observed in 5 cases. There were no further side-effects. The values of gamma-GT, serum-creatinin, hemoglobin and erythrozytes were controlled before and after medication and showed no detremental effect of the drug. The local tolerance of Cefazedone was good in more than 90% of the cases treated.
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PMID:[Cefazedone in infectious diseases in gynecology. Clinical tests on efficacy and tolerance]. 37 73

A study is presented of 500 outpatient abortions performed with paracervical anesthesia before the 12th week of pregnancy. After tests and consultation, 20 mg diazepam was given im 1 hour before the operation. A paracervical blockade was established with 5 ml Carbocainnoradrenalin 1% applied to each of the 4 quadrants. After 10 minutes the cervical canal was dilated a.m. Hegar to 1 number larger than the aspiration curette to be used. The uteral cavity was evacuated by aspiration, at 500 mm Hg vaccuum followed by a stump curette. Patients were given 1 ml Methergin iv during the evacuation, observed for up to 2 hours afterwards, and then sent home. Frequency of perforations with this procedure was .4%, reevacuation 2.0%, adnexitis 1.6%, pyrexia 1.8%, and vasovagal reaction .4%. There was no significant increase in hemoglobin level in patients. 82% of the patients found the method acceptable. The low rate of complications make the method very suitable for outpatient abortions.
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PMID:[Outpatient legal abortion. 500 operations with paracervical anesthesia]. 125 5