Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0001577 (adnexitis)
 232 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Sulbactam (SBT)/cefoperazone (CPZ) is the combined drug of SBT (beta-lactamase inhibitor) and CPZ by 1 to 1 to get spectrum covering much wider range than CPZ only. SBT/CPZ was used in 6 cases of female intrauterine and intrapelvic infections and 3 cases of external genital infections. The clinical efficiency was almost good excluding adnexitis. There were neither subjective and objective side effects nor abnormal laboratory findings.
 ...
PMID:[Clinical evaluation of sulbactam/cefoperazone in obstetric and gynecological infection]. 609 70

Sulbactam/cefoperazone (SBT/CPZ) was administered to 8 cases with gynecologic infections including pelvic peritonitis (2 cases), pyometra (2 cases), acute adnexitis, Bartholin abscess, endometritis and infected lymphocyst. The clinical efficacy was assessed as effective in 7 cases and poor in 1 case. The effective rate was 87.5%. No adverse reactions including clinical signs were observed. But slight elevation of GOT was observed in 1 case.
 ...
PMID:[Clinical studies on sulbactam/cefoperazone in the field of obstetrics and gynecology]. 609 11

Sulbactam (SBT), a new beta-lactamase inhibitor, in combination with cefoperazone (CPZ) to 1 to 1 was clinically studied in the field of obstetrics and gynecology. SBT/CPZ was administered to 13 subjects at a daily dose of 2 g in 2 divided dose by intravenous infusion for 4-6 days. The subjects were patients with the following infections: 2 of intrauterine infections, 5 of intrapelvic infections, 4 of adnexitis and 2 of vulvar infections. The overall clinical efficacy was good in all. Neither adverse reactions nor abnormal laboratory findings were observed in any of the cases.
 ...
PMID:[Clinical studies on sulbactam/cefoperazone in the field of obstetrics and gynecology]. 609 18

Sulbactam cefoperazone (SBT/CPZ), a combination drug of SBT and CPZ, was administered to 5 cases with obstetrical and gynecological infections in a daily dose of 2-6 g for 3-5 days. Clinical efficacy was good in 4 cases and poor in 1 case with adnexitis. Bacteriologically, organisms were detected in 2 out of 5 cases, beta-lactamase producing P. aeruginosa was detected in 1 case, but, their bacteriological responses were not clarified. Neither side effect nor abnormal laboratory findings due to this drug were observed. From the results we concluded that SBT/CPZ was an effective and safe antibiotic in the field of obstetrics and gynecology.
 ...
PMID:[Clinical studies on sulbactam/cefoperazone in the field of obstetrics and gynecology]. 609 19