Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0001577 (adnexitis)
 232 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A role of nutrients in the onset of migraine and other gastrointestinal symptoms (vomiting, nausea, diarrhoea), skin reactions (rush, atopic dermatitis, Quincke'a edema), respiratory symptoms (bronchial asthma, cough, allergic rhinitis, polyps, congestion of the nasal mucosa), motion system disorders (jointache and edema), gynecological disorders (chronic and recurrent adnexitis), and sleep disorders together with emotional tension and behavioral disturbances has been assessed in 17 patients with atopy. Migraine attacks have been produced most frequently by cow milk (in 10 out of 17 patients), cabbage, flour and eggs in 5 patients, preservatives, cottage and Swiss cheese, porcine meat in 4 patients, colorants and chocolate in 3 patients, beef, strawberries, lemons and butter in 2 patients. Other nutrients produced headache in single patients. Migraine and other symptoms have diminished after an individual elimination diet. Recurrence has been noted after each consumption of allergen except one female patient with EEG abnormalities. Immunoglobulins E have been involved in headache-producing mechanism in 3 patients.
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PMID:[Migraine as one of the symptoms of food allergy]. 135 12

Intermittent incomplete intestinal obstruction was proven by sonography in 25 male and 48 female patients with an age range of 10 to 88 years. All of them suffered from intermittent colicky pain, nausea and meteorism followed by liquid stools. Only 52 patients had undergone a total of 69 abdominal operations. The pertinent symptoms could be traced back for 6 months to 10 years (4 +/- 3 years). In 47 patients, intake of bulky food during the last 12 to 48 hours triggered the onset of disorders. The preadmission diagnoses were: incomplete intestinal obstruction (only 21), gastroenteritis (15), biliary colic (13), peptic ulcer (10), renal colic (4), food intoxication (4), appendicitis (3), adnexitis (3). Sonographic findings were: inconstant lumen distension, visible bowel wall movements with contractions of 3 to 6 mm, food bolus, enhanced paradoxical peristalsis, proof of distended and collapsed gut segments, bowel wall edema and free peritoneal fluid. Based on these ultrasonic findings and trend observation, conservative treatment was successfully instituted. All patients were discharged symptom-free with no subsequent attacks for 12 months. 20 patients, subsequently suffering from complete intestinal obstruction after 1 to 3 years, were operated on, comprising 8 cases of intestinal resection, 7 cases of adhesiolysis and intestinal tube splinting, 3 cases of band dissection and 2 cases of palliative bypass procedures. The diagnostic accuracy of abdominal ultrasonography is clearly demonstrated by the fact, that 11 of these patients with intermittent incomplete intestinal obstruction and now suffering from complete obstruction had no previous abdominal surgery.
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PMID:[Intermittent incomplete ileus of the small intestine. Sonographic diagnosis and trends]. 217 61

Fundamental and clinical studies on a new cephalosporin antibiotic, cefpiramide (CPM), was carried out under a joint study program, in order to evaluate the usefulness of the drug in treating infection of the female genital organs. The results obtained were as follows: CPM was readily transported to female genital organ tissues, and the concentrations of the drug exceeded 35 micrograms/g in various organ tissues in about 1 hour, following intravenous injection of 1 g. A level of more than 2 micrograms/g was maintained even 14 hours after the injection. The transport of CPM to various tissues was also studied following intravenous drip infusion of 1 g for 1 hour. The concentrations in tissues were slightly low but similar to those following intravenous injection. The peak concentration of the drug in the dead space exudate was 3.1-20.4 micrograms/ml, following intravenous injection and intravenous drip infusion of 1 g. The MIC80 of CPM were 3.13-12.5 micrograms/ml against S. aureus, Klebsiella sp., P. mirabilis and P. aeruginosa. Clinical effects of CPM were analyzed in 158 patients, including 56 cases with intrauterine infection, 37 cases with intrapelvic infection, 22 cases with external genital infection, 31 cases with adnexitis, 6 cases with postoperative wound infection and 6 cases with other infections. Excellent response was seen in 28 cases (17.7%), good response in 120 (75.9%) poor response in 10 (6.3%). The rate of response was calculated as 93.7%. Safety of the drug was analyzed in 258 patients, and side effects occurred in 4 (1.6%). Of these 4 patients, rash was in 1 patient, heat sensation in 1 patient, nausea in 1 patient and rash accompanying edema in 1 patient. Abnormal values in clinical laboratory findings were seen in 7 patients. Elevations of transaminase were seen in 5 patients and decrease of platelet was seen in a patient, and then elevations of transaminase with decrease of platelet was seen in a patient, and no other changes of particular note appeared.
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PMID:[Fundamental and clinical study on cefpiramide in obstetrics and gynecology. Obstetrics and Gynecology Study Group for Cefpiramide]. 407 5

Twenty-five men with non-specific urethritis/adnexitis were treated with 200 mg doxycycline monohydrate daily (Vibramycin Tabs) over a period of 10 days. More than half of the patients suffered from chronic inflammations. Microorganisms isolated from urethral secretion and prostate exprimate comprised aerobes, in particular staphylococcus epidermidis and streptococcus faecalis, as well as mycoplasmae, chlamydiae, and anaerobes, mainly bacteroides species and peptostreptococci. Fourty percent of patients additionally had anatomical alterations such as constrictions or strictures of the lower urinary tract. After 10-day therapy with doxycycline 16 out of 24 patients (67%) could be cured and a further six patients (25%) could be improved. Microbiological cure could be achieved in infections with chlamydiae in all cases, in infections with mycoplasmae in 67%, in infections with anaerobes in 80%, and in infections with aerobes in 57% of cases. Overall, the therapeutical success in the investigated patient population with chronic infections which are difficult to treat has therefore to be regarded as excellent. Therapy had to be discontinued in one patient after 3 days due to diarrhoea and nausea. In the other patients toleration of doxycycline was good.
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PMID:[Doxycycline in the treatment of non-specific urethritis and/or prostatitis]. 653 88

Antibiotic use was evaluated retrospectively in 1229 patients of a university hospital (Basle, Switzerland). The frequency with which antibiotics were prescribed, the indication, duration of treatment, side-effects and clinical results were compared in relation to various subspecialities. 38.1% of medical, 36.4% of surgical and 24.4% of gynecological patients received one or more antibiotic during hospitalization. The main indications for antibiotic treatment were respiratory infection (57.8%) and urinary tract infections (21%) in medical patients, prophylaxis (38%) and urinary tract infections (23%) in surgery, and urinary tract infections (43%) and adnexitis or endometritis (23%) in gynecology. Amoxycillin or penicillin G were the first-line drugs for respiratory infection, cotrimoxazole for urinary tract infection and cefalothin or cefacetrile for surgical prophylaxis. Patients with endometritis or adnexitis usually received clindamycin in combination with an aminopenicillin. Aminoglycosides were employed in only 9.5% of antibiotic courses. Information on adverse reactions in the records was scanty, only generalized exanthem (13 cases) and nausea/vomiting (2 cases) being specifically mentioned. The therapeutic result was classified by the responsible physician as cure in 50.8% or definite improvement in 16.4% of patients. However, in 118 cases (29.7%) the contribution of antibiotics to the clinical outcome could not be evaluated retrospectively.
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PMID:[Use of antibiotics in hospitalized patients. Comparison of medical, surgical and gynecological units]. 720 74