Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0001577 (adnexitis)
 232 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The influence of copper versus norgestrel-releasing IUDs in cervical and vaginal microflora was investigated prior to and 3 and 12 months after IUD insertion. 90 women were provided with a levonorgestrel-releasing device, while another 50 women were fitted with a copper IUD. The use of an IUD did not lead to any obvious changes in the vaginal or cervical microflora, regardless of type of device. In addition, there were no significant differences in the distribution of various microorganisms between the 2 study groups. None of the study subjects developed pelvic inflammatory disease or symptoms of nonspecific vaginitis during the study period. On the basis of these findings, it was concluded that locally released progestogens from an IUD do not affect the microbiology of either the cervix or the vagina. Any increased risk of adnexitis or nonspecific vaginitis in IUD users thus appears to not result from changes in vaginal or cervical microflora.
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PMID:Microflora of cervical and vaginal secretion in women using copper- and norgestrel-releasing IUCDs. 312 15

Most infections occurring after an interruption of pregnancy (IP) are not due to the physician's negligence but rather to the patient's failure to follow treatment guidelines at home, especially their sexual activity and hygiene. The causes of secondary sterility were most often found to be parametritis with adnexitide or adnexitis on 1 or both sides. In a smaller percentage of cases there occurred salpingitis, cervicitis, colpitis, endometritis, and even pelveoperitonitis. It is not only infections that can cause sterility but disorders of the menstrual cycle (hypermenorrhagy, amenorrhagy) as well. The onset and the intensity of infection after IP is definitely dependent on the technique of the actual operation, the length of hospitalization, care at home after release from the hospital, and on the month of pregnancy when IP was performed.
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PMID:[Long-term follow up of secondary sterility following artificial interruption of pregnancy]. 547 33

Six months after an attack of pyelonephritis, adnexitis and candida colpitis an 18-year-old girl developed some clouding of consciousness. On neurological examination she showed organic behavioural changes, discrete anisocoria and possible meningism. Computed tomography revealed hydrocephalus and signs of increased cerebrospinal fluid (CSF) pressure. CSF contained 2336/3 cells, while total protein was raised to 7.0 g/l and lactate concentration to 6.85 mmol/l. Glucose concentration in CSF was 51 mg/dl and 75 mg/dl in serum. As tuberculous meningitis was suspected, treatment was started with four tuberculostatic drugs, but there was no improvement. Five weeks later microscopic CSF examination showed fungal spores and nonbranching hyphae. The maximal candida haemagglutination titre in CSF was 1:2048. CSF culture grew Candida albicans. The further course was complicated by side effects to the antimycotic drugs (amphotericin B between 4.5 and 45 mg daily; flucytosine 1.7 g four times daily) and recurrent obstruction in the ventricular system requiring repeated neurosurgical interventions. However, full cure was achieved after seven months' hospital treatment.
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PMID:[Unusual course of candidiasis of the central nervous system]. 828 77

Menstrual function and gynecologic morbidity were studied in 4202 female students from medical, engineering, and chemical institutes. They were found to have algomenorrhea, ovary dysfunction, algo-hyper-polymenorrhea, hyper-polymenorrhea. Among genital inflammations there were predominant erosion of the cervix uteri, adnexitis, and colpitis. After therapeutical and conditioning measures the vast majority of girls convalesced.
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PMID:[Prevention of gynecologic diseases in women students of higher educational institutions]. 1153 Jun 38

Morbidity data from the dispensary of the district of Sangha, Mali, are analyzed. The morbidity data do not precisely mirror the health situation of the district because some villages located 2 or 3 hours away have less recourse to the dispensary. Data were collected for May, when the dry season ends, and September, when significant rainfall occurs. 578 persons were treated in May. The parasite Schistosoma haematobium, which is present in shallow and stagnant water and around onion fields, was the largest single cause of consultation. Schistosoma haematobium causes genital bilharziasis leading to sterility in women, genitourinary infections, and neoplastic bladder disease. A number of women had combined vaginitis-adnexitis causing tubal obstruction, and some also had uterine fibromas. Almost 20% of consultations were concerned with pathologies of the urinary or genital tracts. In all, 47.2% of consultations were for parasitic diseases including 28.4% for bilharziasis; 17.8% for bacterial diseases including 8.1% for gonorrhea, 5.7% for anemia, 5.3% for gastroenterologic problems, 3.1% for ophthalmologic problems, and 20.9% for other or poorly defined causes. The dusty air in the end of the dry season was the cause of colds which sometimes led to bronchopneumopathies. Intestinal parasites accounted for less than 3% of consultations. There were 537 consultations in September 1991. Parasite infections again accounted for 45.7% of consultations, with 15.1% due to malaria. Bacterial diseases accounted for 16.9%, with gonorrhea responsible for 9.2%. 4.3% of consultations were for anemia, 9.8% for gastroenterological problems, 4.5% for ophthalmologic problems, and 18.8% for other or poorly defined causes.
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PMID:[Aspects of the pathology of the Dogon of Sangha]. 1228 96

Trichomonas vaginalis is the most common non-viral sexually transmitted pathogen. The infection is prevalent in reproductive age women and is associated with vaginitis, endometritis, adnexitis, pyosalpinx, infertility, preterm birth, low birth weight, bacterial vaginosis, and increased risk of cervical cancer, HPV, and HIV infection. In men, its complications include urethritis, prostatitis, epididymitis, and infertility through inflammatory damage or interference with the sperm function. The infection is often asymptomatic and recurrent despite the presence of specific antibodies, suggesting the importance of the innate immune defense. T. vaginalis adhesion proteins, cysteine proteases, and the major parasite lipophosphoglycan (LPG) play distinct roles in the pathogenesis and evasion of host immunity. LPG plays a key role in the parasite adherence and signaling to human vaginal and cervical epithelial cells, which is at least in part mediated by galectins. The epithelial cells respond to T. vaginalis infection and purified LPG by selective upregulation of proinflammatory mediators. At the same time, T. vaginalis triggers an immunosuppressive response in monocytes, macrophages, and dendritic cells. The molecular mechanisms underlying reproductive complications and epidemiologic risks associated with T. vaginalis infection remain to be elucidated.
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PMID:Impact of T. vaginalis infection on innate immune responses and reproductive outcome. 1985 Mar 56