Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0001577 (adnexitis)
 232 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

It was shown that the risk for endometrial cancer development in uterine myoma increases 43-fold in cases of diabetes mellitus, hypertension and obesity, 20-fold in adnexitis, 15-fold in hyperplastic endometrial lesions and 9.8-fold in the multipara.
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PMID:[Risk factors for the development of endometrial cancer in uterine myoma]. 402 48

Cefpimizole (AC-1370) was administered to 5 cases with uterine myoma before hysterectomy, and tissue distribution was determined. AC-1370 was also administered to 5 cases with gynecological infections. The following results were obtained. One gram of AC-1370 was administered from 43 to 299 minutes before hysterectomy, tissue distribution of AC-1370, such as ovary, oviduct, myometrium, cervix uteri, and portio vaginalis was showed the highest level (30.0 approximately 49.5 micrograms/g) at 43 minutes after administration, and these were 39.0 approximately 64.4% of the concentration in uterine arterial blood. Tissue concentration of AC-1370 was then gradually decreased following with the decreasing of the concentration in uterine arterial blood. AC-1370 was administered to 3 cases with pyometra, 1 case with Bartholin abscess, 1 case with adnexitis. The clinical efficacy was good in all 5 cases. Bacteriological study revealed that A. faecalis and E. coli were eradicated, but B. fragilis was persisted. No side effect was observed in all cases.
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PMID:[Evaluation of the clinical effect and tissue distribution of cefpimizole in the field of gynecology]. 403 28

Serious complications of IUDs in 4 young women are reported. The 1s t patient, 21 years old, developed severe adnexitis 6 months after insertion of a Lippes loop. The IUD was removed and antibiotic treatment was successful; the patient has since borne a child. The 2nd patient, 23 years old, developed an inflamed right tubal cystic tumor 2 years after insertion of a Lippes loop immediately following induced abortion. Recurrent inflammatory episodes were treated with anitbiotics, but peritonitiss developed and bilateral salpingo-ovariectomy was necessary. The 3d patient, 38 years old, developed peritonitis and septic shock after removal of a "butterfly" IUD which had been inserted 8 months earlier; this patient had previously been treated for uterine myoma. Laparotomy, drainage and antibiotic treatment were successful. The 4th patient, 25 years old, became pregnant 2 months after insertion of a Majzlin spring; uterine perforation resulted from her physician's attempts to remove the device (which could not have endangered the pregnancy). The injury was sutured and curettage was performed. All these cases were due to insufficient attention to contraindications of IUD USE.
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PMID:[A report of four cases with serious complications after insertion of an intrauterine contraceptive device (author's transl)]. 483 95

Total postoperative complications after induced abortion in the German Democratic Republic is 9.7%. This increases to 20% in women over 35 years old with a uterine myoma and concurrent pregnancy. Necrotic degeneration of a myoma following induced abortion is rare in the literature. A 43 year old patient presented for therapeutic abortion at 3 months pregnancy. A uterine myoma of the posterior wall was found at preoperative evaluation. Vaginal suction evacuation was performed under anesthesia. After subsiding of symptoms further gynecological palpation showed a fist-size, painful, retroflexed uterus with painful adnexa and Douglas' pouch. Antibiotics were used to treat the adnexitis. Diminishing of symptoms did not result in decrease of uterine size and laparotomy was done for suspected degenerative softening of the myoma. Partially necrotized uterine myoma, solidly encased in the Douglas' pouch, was found and radical hysterectomy was performed. Except for a successfully treated urinary infection the postoperative course was smooth and patient was discharged on day 17. Histology findings were nonmalignant, fibrosed intramural leiomyoma of the uterus. Degenerative changes of uterine myomas are most likely caused by nutritional deficiency of the myoma. Space restriction following therapeutic abortion, risk of possible tissue trauma, thrombus formation and bacterial infection can all induce the necrotic process. Necrosis of uterine myomas should be considered as a possible complication in a typical postoperative course of therapeutic abortion.
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PMID:[Necrotic uterine myomatosis--a rare complication following vaginal termination of pregnancy by suction (author's transl)]. 726 82