Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0001577 (adnexitis)
 232 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Based on many years' experience with trichomonas vaginalis the author comes to the conclusion that trichomonads are much more common than expected. Therefore the possibility of trichomoniasis shoudl be taken into account not only when discharge is found in females or persistent urethritis in males, but also in other affections. Remote reactions may occur in either sex, e.g. prostatis or adnexitis. Sterility is sometimes due to trichomonas vaginalis. Apart from classical pictures in either sex arthritis and erythema nodosum may develop. The unstained preparation is usually sufficient for demonstrating the organism. The clinical diagnosis in males and females is discussed. The new single dose therapy with tinidazole is of special interest for three reasons: low minimum trichomonacidal concentrations, 72-hour-action, high active excretion in the urine. No effect on the blood picture was observed. It appears that tinidazole (Simplotan) has a secondary effect on the pathological mixed flora. Candida, too, is often eliminated, but in some cases nystatin therapy is still necessary. The relations to diabetes mellitus, antibiotics, pregnancy and hormonal contraception are discussed.
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PMID:[Trichomoniasis. Physiopathology and therapy]. 30 Jul 4

221 non-smoking women and 1200 women who smoked 4-40 cigarettes/day were examined in a counselling center for childless couples. An endometrial biopsy, tests for trichomoniosis and adnexitis, salpingography, and information on menstrual bleeding were taken as part of the examination. The results of the endometrial biopsy and the frequency of ovarian disorders were similar for both groups. The incidence of trichomoniasis, adnexitis, and pathological findings of the salpingography were ca. 40-50% higher among smokers. Menstrual disorders were more frequent only among women who smoked more than 10 cigarettes/day. The effect of smoking on the incidence of inflammmatory infections appears to be indirect.
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PMID:[Sterility in female smokers and nonsmokers]. 549 2