Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0001577 (adnexitis)
 232 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The article presents a review of the evolution of indications for laparosocpy during the years 1973-1977. Laparoscopy is always indicated in case of chronic pelvic pains, ovarian malignant tumors, tubal infertility, adnexitis or ectopic pregnancy. In such cases the accurate inspection of the pelvic cavity can allow precise diagnosis and therapy. Laparoscopy can also be repeated to control the effectiveness of therapy, especially in the surveillance of ovarian cancers. On the other hand, laparoscopy should not be systematically performed in cases of isolated pelvic pains, in case of ovarian cyst or fibroma, or in case of amenorrhea, where clinical examinations and biological explorations are sufficient to determine diagnosis and therapy. Laparoscopy should be used only when there are contraindications among biological findings, or in cases of therapeutic failures.
 ...
PMID:[The evolution of the indications for laparoscopy between 1973 and 1977. 1,758 cases (author's transl)]. 16 66

Lymphoid adenohypophysitis is an autoimmune disorder. Eighteen percent of the multipartums are reported to have autoantibodies to pituitary tissues. The symptoms in lymphoid adenohypophysitis, such as hypopituitarism and sellar tumors, exhibit spontaneous remission. The pituitary is a feasible target organ in other autoimmune diseases of the endocrine system. Of these patients, 19/287 showed a positive immune reaction with pituitary tissue antigens. Our three female patients with sellar and suprasellar mass were clinically diagnosed as having lymphoid adenohypophysitis, because of the spontaneous regression of tumors, or presence of immunologically and endocrinologically abnormal findings. The first case was a 31-year-old woman who had amenorrhea and galactorrhea syndrome for two years after delivery of her second child. CT scan revealed a supraseller enhanced mass lesion. She had concomitant signs of recurrent meningeal irritations. The number of cells in the CSF increased, though the protein concentration increased only slightly. During a one-year close observation, the suprasellar mass spontaneously regressed. The second patient was a 66-year-old woman. In 1945, she underwent hysterectomy and oophorectomy for appendicitis followed by adnexitis. She was admitted because of episodes of headache, vomiting and visual field defect in 1983. CT scan also showed a contrast enhanced mass in the suprasellar region. She had two episodes of high fever. After the treatment with antibiotics and anti-inflammatory agents for 4 months, the tumor disappeared. The third case was a 20-year-old female. She had neither neurological nor endocrinological abnormality, except for attacks of vertigo, nausea and vomiting.(ABSTRACT TRUNCATED AT 250 WORDS)
 ...
PMID:[Lymphoid adenohypophysitis, with special reference to 2 cases with sellar tumors spontaneously disappearing on the CT]. 377 4

The gynecologic department of the Magdeburg Medical Academy has a special clinic where adolescents can come for sex, contraception, and abortion counseling. Current life-style has increased sexual behavior among adolescents; age of menarche comes earlier (12.6 yrs); cohabitation occurs at an earlier age. With increase in heterosexual activities comes increase in unwanted pregnancy and venereal diseases. The clinic engages in personal and group counseling on all aspects of sex life, family life and planning, and contraceptive methods. In the past 10 years 18,000 adolescents between the ages of 14 and 17 have been counseled. Of these, 610 subjects were counseled in the contraceptive clinic. Timely use of contraceptives by adolescents is still inadequate: only 12.8% of these girls used contraception before 1st sexual relations (10.5% hormonal, 2.3% diaphragm); 12.6% had a pregnancy before 1st contraceptive use of which 88.3% had an abortion. The question of side effects of oral contraceptives in adolescents concerns: 1) growth suppression - this is not likely because growth after menarche is usually no more than about 6 cm; 1) thromboembolism - there are few predisposing factors in adolescents, except in those who smoke; and 3) endocrinological problems - it is important that a stable biphasic ovulatory cycle exists; the risk of postpill amenorrhea must be considered. The minipill (progestin only) is prescribed to those with menstrual irregularities; sequential contraceptives (Ovosiston) to those with stable biphasic cycles before age 16; combination contraceptives (Minisiston) to those with stable cycles after age 16. With contraindications to the pill, the use of IUDs is considered after careful history taking in relation to earlier endometritis and/or adnexitis. Other methods such as rhythm methods or mechanical barriers are also considered. The most important aspect in contraceptive and sexual counseling of adolescents is an open and individualized approach.
 ...
PMID:[Experiences from a sex-counseling and birth control practice for adolescents]. 685 18

Bacterial vaginosis are characterized by a polymicrobial proliferation of anaerobic organisms and the disappearance of the commensal lactobacilli, which can cause ascending utero-adnexitis and endanger ongoing pregnancy. The role of anaerobes in utero-adnexitis and tubal abscess was first raised in 1973 par Eschenbach. Several authors have since established correlations between bacterial vaginosis and both pain from the uterine appendages and gynecologic infections, particularly post-abortum. Bacterial vaginosis is a major problem in pregnant women, given its high prevalence (15-20 p. cent) and significant relationship with premature delivery and premature rupture of the membranes (at less than 37 weeks of amenorrhea) in epidemiological case-control and cohort studies taking into account demographic and concomitant obstetric characteristics. In particular, histological lesions indicative of chorioamniotitis have been correlated with prematurity and with the presence of bacteria (usually those involved in vaginosis) in the amniochorial space. Bacterial vaginosis can give rise to ascending infections which reach the amniochorial space and cause uterine contractions or alter the amniochorial membrane, leading to premature rupture of the membranes. These epidemiological data must, however, be confirmed by controlled trials of antibiotics active in bacterial vaginosis and their preventive effect on prematurity and premature rupture of the membranes. Finally, bacterial vaginosis can play a role in endometritis following both natural and caesarean delivery; this has been shown in multivariate analyses with adjustment for maternal age, duration of labor and rupture of the membranes, and isolation of bacteria associated with bacterial vaginosis from the endometrium.
 ...
PMID:[Bacterial vaginosis: what risks for the mother and child?]. 848 90

Endometriosis is certainly responsible for many instances of infertility, although its physiopathological mechanism is not very clear. Tubal endometriosis can lead to occlusion of the tubes, ovarian endometriosis can cause adhesions, and peritoneal endometriosis can cause adnexitis. Sterility caused by endometriosis is often secondary, while amenorrhea, menstrual fever, and pain are always present. Clinical medical examinations should be completed by hysterography and celioscopy. Endometriosis can be treated with hormonotherapy: lynestrenol and norethindrone atrophy the endometrium, block ovulation, and cause persistent amenorrhea. Surgical treatment has benefited enormously from the recent progress in microsurgery; it is now possible not only to resect the unwanted tissue, but to reconstitute the healthy one. It would be now reasonable to expect a pregnancy in about 50% of treated cases.
 ...
PMID:[Endometriosis and infertility]. 1233 3