Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0001577 (adnexitis)
 232 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The case-study of genital actinomycosis in a 33-year old woman wearing a "Copper T200" IUD is presented. She was hospitalized and treated for lower abdominal pain and non-characteristic signs of adnexitis twice. Adnexectomy on the left side was performed to remove an orange-size cyst. Histo-pathological examination of a prepared tissue sample revealed a colony of Actinomyces. Following the operation the patient was treated with 3 x 500 mg Flagyl (metronidazole) 3 x 80 mg of Gentamicin im. The wound healed in 19 days after operation. This woman had worn the IUD continuously for more than 3 years, thus there was an increased risk of uterine lesions. The most frequent consequences of wearing IUDs for a long time are dysmenorrhea and endometritis and therapeutic approaches are detailed. Since its first description in the literature in 1857 actinomycosis has not been mentioned frequently. However, with the spread of IUDs, the number of actinomycosis-like cases has increased and this justifies the need for improved diagnosis. The frequency of actinomycosis occurring in women wearing IUDs ranges between 1.6% and 19.7%
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PMID:[Adnexal actinomycosis in a woman using an intrauterine contraceptive device (IUD)]. 358 37

A rare observation--ovarian actinomycosis in a woman of 42 which had clinical manifestations of chronic adnexitis and was diagnosed pathomorphologically--in described. Destructive variant of mycotic process resulted in pelvioperitonitis with a subsequent surgical operation. This case may be referred to as a primary genital actinomycosis.
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PMID:[Primary ovarian actinomycosis]. 400 78

Abdominal actinomycoses with genital localization are relatively rare, but their occurrence has been increasing recently due to more extensive use of IUDs. After a brief review of the etiology, diagnosis, and treatment of this disease, 3 cases of IUD-induced genital actinomycosis are described. All 3 women were in their 40s. In 2 cases, the disease developed within a week after the IUD had been extracted. The patients were hospitalized with a diagnosis of adnexitis, which was confirmed by histological tests, anaerobic cultures, and microscopic examination. In all 3 cases, surgery was followed by antibiotic therapy with megadoses of crystalline PNC, Entisol, and subsequent long-term treatment with ampicillin. The treatment was successful; the women recovered to an almost normal gynecological condition.
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PMID:[Actinomycoses of the female genitalia in connection with IUD insertion]. 404 74

The occurrence of actinomyces infection following IUD insertion was observed by the authors in 2 cases. A pathogenetic role has been positively ascribed to the IUD. In 1 case, actinomycosis was histologically confirmed on a surgically removed IUD and was accompanied by severe tuberculoid tissue reaction. In the 2nd case, actinomyces colonies were recorded and identified from the IUD which had been removed for adnexitis. Success was obtained by early medication. Prevention and early detection will be possible by vaginal smears prior to insertion of an IUD and with the latter in place after some time as well as by testing the IUD proper for actinomycosis after its removal. (Author's modified)
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PMID:[Genital actinomycosis, following insertion of intra-uterine device (IUD) -- possibilities for prevention (author's transl)]. 723 5

The authors describe a case of ovarian actinomycosis in a 50-year-old female. The initial signs of adnexitis were followed by tumor signs. The treatment included surgery and specific immunotherapy.
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PMID:[Ovarian actinomycosis]. 794 79