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Query: UMLS:C0001511 (Adhesion)
 5,955 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Adhesion of 51Cr-labeled rat erythrocytes was examined in a layer of glass beads in a dynamic system. The kinetics of erythrocyte retention in the bead layer was found to change with time. Adhesion decreased with time at all the studied rates of suspension flow through the layer (within the range 1-5--0-4 cm/min), both in presence and absence of serum in the medium. Serum in low concentrations of 20--200 microgram of protein per ml considerably inhibited dynamic adhesion of erythrocytes to glass. The higher the serum concentration in a medium (at a definite flow velocity), the quicker the decrease of adhesion with time, and the stronger the dependence of the kinetics of erythrocyte retention on the flow velocity of the cells. Mean adhesion of erythrocytes after 17-min perfusion of the layer (at 200 microgram of serum protein per ml of medium) seems to be independent of the concentration of the cells in the suspension flowing into the layer within the range of studied concentrations, 2 x 10(6)--20 x 10(6) cells/ml. However, mean adhesion of erythrocytes deprived of serum seems to be dependent on the cell concentration.
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PMID:Dynamic adhesion of erythrocytes to glass. Comparative study of the influence of serum in low concentrations. 88 29

Adhesion of cells to a biomaterial surface can be a major factor mediating its biocompatibility. In this investigation, jet impingement techniques were used to quantify strength of cellular adhesion to various material surfaces. The metals tested: HS25 (a cobalt-based alloy similar to F75), 316L stainless steel, Ti-6Al-4V, and commercially pure tantalum, exhibited nearly a fivefold increase in adhesion strength above that characteristic of the polymeric materials tested (PTFE, silicone rubber, and HDPE). The present study examines physical and biological factors that might influence fibroblast adhesion to the biomaterial surface. The relation between surface charge and cellular adhesion was investigated in a controlled manner by measuring adhesion strength over a range of charge densities. The cells showed charge and electrical potential-dependent adhesion maxima, suggesting that surface alloying for optimum adherence may be possible. In a preliminary series of experiments adsorbed serum protein layers on a series of materials of differing adherence were investigated using gel electrophoresis to assess protein composition. Analysis of adsorbed proteins revealed little difference in relative abundance or total adsorption quantity. SEM micrographs of cells on Ti-6Al-4V and silicone rubber (high and low adhesion materials, respectively) demonstrated differences in cell morphology and cell density.
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PMID:Cell adhesion to biomaterials: correlations between surface charge, surface roughness, adsorbed protein, and cell morphology. 1017 29