Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0001486 (Adenovirus)
 3,125 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The major findings and conclusions of the present study are: 1. Evidence of the etiology of the pneumonia was established in 86% of 106 young men with pneumonia. Pneumococcus was the most common etiologic agent; it was detected definitely in 30% of the pneumonia patients, and possibly in another 20%, by blood culture, sputum culture, antigen detection, and serological methods. 2. Pneumococcal antigen detection from purulent pretreatment sputum samples was the best rapid diagnostic method for pneumococcus; it was capable of identifying 90% of the pneumococcal pneumonias definite by our criteria, whereas sputum Gram stain was positive in 65% of these. 3. Detection of adenoviral antigens from nasopharyngeal specimens (NPS) by EIA or IF method or adenovirus DNA by HYB method showed good specificity but a somewhat lower sensitivity than did adenovirus isolation from NPS. 4. Adenovirus antigens and DNA can be demonstrated also from sputum specimens. 5. EIA is slightly superior to the CF method in detecting antibody responses to adenovirus, but the detection of different antibody classes offers no additional diagnostic possibilities. 6. Isolation of Mycoplasma pneumoniae from bronchoalveolar fluid in pneumonia patients is a specific and sensitive method in the diagnosis of mycoplasmal pneumonia. 7. It seems possible to differentiate by clinical signs and symptoms and by high CRP (over 85mg/1) and WBC (over 10 x 10(9)/1) values pneumococcal pneumonias from viral, mycoplasmal and mixed pneumonias and from upper respiratory infections. Moderately elevated CRP values were observed in adenoviral (Mean 50 mg/1) and in mycoplasma (mean 59 mg/l) pneumonias, as well as in MRI (mean 44 mg/l).
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PMID:Rapid etiological diagnosis of pneumonia in young men. 318 95

Laboratory-based surveillance for diarrheal and respiratory illness was conducted at the 2009 Republic of the Philippines-United States Balikatan exercise to determine the presence of specific pathogens endemic in the locations where the military exercises were conducted. Ten stool and 6 respiratory specimens were obtained from individuals meeting case definitions for diarrhea or respiratory illness. Stool specimens were frozen in dry ice and remotely tested using enzyme-linked immunosorbent assay for Rotavirus, Astrovirus, Adenovirus, Entamoeba histolytica, Giardia, and Cryptosporidium and polymerase chain reaction for enterotoxigenic Escherichia coli, Campylobacter, Shigella, Vibrio, Salmonella, and Norovirus. Eight (4 for Campylobacter jejuni, 2 for Campylobacter coli, 1 for Norovirus genogroup II, and 1 for both Campylobacter coli and enterotoxigenic Escherichia coli) of 10 samples were positive for at least 1 enteric pathogen. MassTag polymerase chain reaction for influenza A and B, respiratory syncytial virus groups A and B, human coronavirus-229E and human coronavirus-OC43, human metapneumovirus, enterovirus, human parainfluenza viruses 2,3, and 4a, human adenovirus, Haemophilus influenzae, Neisseria meningitidis, Streptococcus pneumoniae, Legionella pneumonia, and Mycoplasma pneumonia was done on respiratory specimens. Out of 6 samples, 3 tested positive for H. influenzae; 1 tested positive for both H. influenzae and human parainfluenza virus 3; and 2 tested negative. Laboratory-based surveillance can be useful in determining etiologies of diarrheal and respiratory illness of deployed military personnel.
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PMID:Applications of PCR (real-time and MassTag) and enzyme-linked immunosorbent assay in diagnosis of respiratory infections and diarrheal illness among deployed U.S. military personnel during exercise Balikatan 2009, Philippines. 2212 41