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Query: UMLS:C0001486 (Adenovirus)
 3,125 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Some problems concerning the use of antiviral vaccines are reviewed. Particularly various aspects regarding both intensively used vaccines (small-pox, polio and influenza) and selectively used vaccines (measles, mumps, rubella, parainfluenza and Adenovirus) as well as vaccines under testing (anti-V-Z and hepatitis) are evidenced.
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PMID:[Advances in the field of antiviral vaccines]. 626 66

Surveillance of febrile respiratory diseases at Lowry Air Force Base, Denver, has been maintained from 1952 to 1982 with laboratory confirmation of diagnosis. Unvaccinated recruit populations were extremely vulnerable to explosive outbreaks of influenza A. Ten controlled trials demonstrated the protective efficacy of inactivated vaccines. Recent military vaccines have raised the hemagglutination-inhibiting antibody levels of most persons into the "protective" range. Despite repeated introduction of influenza viruses onto the base, when all personnel were vaccinated the impact of influenza was reduced to an insignificant level except in one year of antigenic shift (1968) and one of major antigenic drift (1972). Adenovirus disease has been virtually eliminated since live oral types 4 and 7 vaccines have been given to incoming recruits. Rubella and rubeola have disappeared since seronegative recruits have received vaccine. Overall rates of febrile respiratory diseases have been greatly reduced.
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PMID:Viral respiratory disease at Lowry Air Force Base in Denver, 1952-1982. 631 18

Viruses were shown to be present in the respiratory tract in 200 of 763 cases of the sudden infant death syndrome studied in the nine years 1974-82. Epidemiological and pathological evidence suggested that the distribution of viruses in the sudden infant death syndrome differs between infants aged 3 months or less and those aged over 3 months: the incidence of detection of virus was 14% in the younger group compared with 39% in the older group. The distribution of the viruses in these two groups was compared with that in 1341 live infants with respiratory virus infections. Adenovirus, influenza virus, parainfluenza virus, and rhinovirus had similar distribution among the victims of the sudden infant death syndrome and live controls. The incidence of detection of respiratory syncytial virus was increased in the older infants dying of the sudden infant death syndrome (90% of the cases detected) compared with the older group of live infants (53%). Antibody studies, detection of virus, and epidemiological data suggest that respiratory syncytial virus may be a precipitating factor of sudden death in older infants.
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PMID:Respiratory viruses and sudden infant death. 642 15

The etiology of mild myocarditis, diagnosed on the basis of serial ECG changes during an acute infection, was studied in 126 consecutive conscripts. A fourfold rise in the antibody titers in the paired serum samples was required for a positive etiologic diagnosis. An etiologic diagnosis was made probable in 47% of the patients. Adenovirus was incriminated in 19 patients, vaccinia in 12, influenza A in eight, beta-hemolytic Streptococcus in six, mononucleosis in five and Mycoplasma in three. Chlamydia, influenza B and Coxsackie B4 were each found in two patients; parainfluenza, mumps and adult Still's disease were each found in one patient. The incidence of vaccinia myocarditis was 1/10000 smallpox vaccinations. Clear-cut myopericarditis was usually noted during vaccinia, mononucleosis, Mycoplasma, Chlamydia and Coxsackie B4 infections. Adenovirus and influenza A myocarditis was most often subclinical, being mostly detected only because of ECG screening of patients without cardiac symptoms. Frequent recent ventricular extrasystoles were most often triggered by a beta-hemolytic Streptococcus infection. The etiology of infectious myocarditis seems to reflect the overall profile of viruses and other infective agents in the study population at that particular time. Cardiotrophic viruses such as Coxsackie B only rarely cause myocarditis outside epidemics.
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PMID:Etiology of mild acute infectious myocarditis. Relation to clinical features. 682 23

The 17-year observation of changes in the etiological pattern of acute respiratory diseases (ARD) in the country has demonstrated that different types of adenoviruses are prevalent in the circulation on the whole territory. Adenoviral infection was found to prevail among non-influenza infections in the Ukraine, RSV infection in the north of the Russian Federation and in the Far East; piconaviral infections caused by Echo and Coxsackievirus B in the Urals and Byelarus Republic. However, some years were marked by a change in various serotypes of adenoviruses and picornaviruses in different climatic and geographical zones and in different age population groups. There was a seasonal variability in the spread of respiratory viruses and herpes simplex virus type I. Adenovirus infection is characterized by fall-winter-spring seasonal patterns. RSV-infection and herpes infection are characterized by fall-winter seasonal patterns. In contrast, the acute respiratory infections of picornavirus etiology show a well-defined summer seasonal pattern.
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PMID:[Some characteristics of circulation and respiratory viruses in the country]. 753 99

Non-specific interstitial pneumonia (NIP) occurs frequently in patients with HIV-infection. To elucidate the etiology of this pulmonary disorder, we searched for 13 different microorganisms in transbronchial biopsies from 15 patients with NIP, 15 patients with Pneumocystis carinii pneumonia (PCP) and 20 patients with lung diseases not related to HIV-infection using monoclonal antibodies and the APAAP- or PAP-technique for immunostaining. Chlamydia trachomatis and parainfluenza III were detected frequently and in great number. Adenovirus, influenza B, varicella zoster and cytomegalovirus were also found frequently, but not in great number. Measles virus, respiratory syncytial virus, influenza A and herpesviruses 1&2 were not found. Also not found were parainfluenza I, mycoplasma pneumoniae and coronavirus. In seven out of fifteen NIP patients at least one organism was shown, compared to nine out of fifteen patients with PCP and eight out of twenty patients in the control group.
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PMID:Non-specific interstitial pneumonia (NIP): immunohistologic screening of etiologic agents. 789 90

This study retrospectively reviewed those pediatric patients of acute lower respiratory tract infection with positive virus identification by direct immunofluorescence assay (Direct IF) from Jan, 1992 to Dec, 1993. One hundred and eighteen patients with 133 positive Direct IF results (107 cases with single virus identified, and 11 cases with more than one) were included. The sex ratio was 1.6:1 with males predominant; age, 22.1 (1 approximately 154.8) (months); duration of admission, 5.7 (1 approximately 69) (days); peripheral white blood cell count, 10,600 +/- 3,800/mm3; C-reactive protein, 17.0 (0 approximately 163.3) mu/ml; body temperature, 37.1 +/- 1.1 degrees C in those cases with single virus. The symptoms were cough 105 cases (98.1%), rhinorrhea 46 cases (43.0%), dyspnea and/or tachypnea 43 cases (40.2%) and diarrhea 15 cases (14.0%). The viruses identified were: Adenovirus (52 cases, 39.1%). Influenza B (45 cases, 33.8%), Parainfluenza 1 (28 cases, 20.1%), Parainfluenza 3 (19 cases 14.3%), Respiratory Syncytial virus (17 cases, 12.8%), and Influenza A (9 cases, 6.8%). The seasonal incidence rates were spring (49 cases, 36.8%), summer (46 cases, 34.6%), autumn (23 cases, 17.3%), and winter (15 cases, 11.3%). The results showed much similarity with others, except the commonest viral type (Adenovirus in this study; Respiratory Syncytial virus in others) and the seasonal incidence rate (higher in spring and summer in this study but not in others). In conclusion, most children with acute viral lower respiratory tract infection had an uneventful course and Direct IF is a reliable method for viral detection in that disease.
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PMID:Study on the children of Kaohsiung with acute viral infection of lower respiratory tract by direct immunofluorescence assay. 798 92

Children who had previously received Morbilli-(Mumps) Rubella (MMR) vaccine developed parotid swelling which was diagnosed as acute parotitis 7 days to 2 years following inoculation. Blood samples from each of the patients were tested for the following virological parameters: Mumps-virus, Parainfluenza-viruses (PIV) type 1., 2., 3., Respiratory Syncytial Virus (RSV), Epstein Barr Virus Capsid Antigen (EBVCA) IgM, IgA, IgG immunofluorescent test (IFT) and EBVCA IgM, IgG ELISA (HUMAN); Epstein Barr Virus Early Antigen (EBV EA) IgG IFT; Adenovirus, Influenza A, B Complement Fixation (CF) test. Some of the sera were examined for CMV IgM, IgG ELISA (Organon Teknika) and Human Parvovirus B19 IgM, IgG recombinant ELISA (Bender) too. Nine cases were interpreted as a clinical reaction of mumps vaccination. Beside the clinical reaction of mumps vaccination. Beside the clinical reaction of mumps vaccination, the etiological role of PIV-1, PIV-2, PIV-3 and PIV-1,2 was confirmed in four, three, one and one patients, respectively. The alonely etiological agent was the PIV-2 in four and PIV-2 and Epstein-Barr virus together were in one patients, respectively. The etiology was unknown in one patient. The results show the importance both of the broad spectrum precise serologic studies and of the skillful interpretation in the exact diagnosis of the acute parotitis to identify parotitis either as a consequence of the mumps vaccine or vaccine failure. The correct diagnosis of acute parotitis can influence the booster mumps vaccination practice too.
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PMID:[Acute parotitis in children previously vaccinated against mumps]. 830 84

Viral laboratory diagnosis was correlated with clinical and epidemiological data from 80 hospitalized children with acute lower respiratory infection (ALRI). They all were less than 5 years-old and were studied from May to September 1993. Fifteen percent of them were malnourished and 75% had some unsatisfied basic necessity. Nasopharingeal aspirates were obtained the first day of hospitalization, and diagnosis for respiratory viruses was performed by the immunofluorescence test with monoclonal antibodies. Routine laboratory determinations, x-ray studies, and clinical data were not conclusive to determine viral etiology. Forty-one percent of the children had a positive viral diagnosis: the most important agent was Respiratory Syncytial Virus (78.7%) followed by Adenovirus (9.1%), Influenza A (6.1%) and Parainfluenza (3%). The peak of incidence was observed in June and the majority of the patients remained hospitalized less than 10 days. Six children died: two of them had viral pneumonia and could not receive mechanical respiratory assistance. The percentage of children who received antibiotics was high, 61.2%, in spite of the fact that 34.7% of these patients had a laboratory confirmed viral etiology. The availability of rapid laboratory viral diagnosis may contribute to decrease the use of antibiotics and improve the management of patients.
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PMID:[Etiological and clinical evaluation of low acute respiratory infections in children]. 903 75

An immunoglobulin G of mouse was purified from sera by affinity chromatography in protein A. The rabbits whose sera were able to recognize the antigen injected by double immunodiffusion were immunized with this preparation. The antibodies were precipitated from the rabbit's serum and purified by ion exchange chromatography. This preparation was conjugated to fluorescin isothiocyanate according to the conventional technique. The conjugated obtained was evaluated with the reference strains of Parainfluenza virus 1, 2, 3; Adenovirus; respiratory syncytial virus; and influenza virus A and B, by an indirect immunofluorescence technique and HIV positive samples by flow citometry. Specific monoclonal antibodies were used in both cases. Clinical specimens of patients with acute respiratory infection were evaluated.
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PMID:[Evaluation of a mouse anti-IgG-fluorescein conjugate using indirect immunofluorescence and flow cytometry techniques]. 968 74


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