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Query: UMLS:C0001430 (adenoma)
 21,222 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Ceruminoma is a rare form of tumor in man. Most of them are found in the external ear, rarely in the middle ear. The authors review the relevant literature and report a case of ceruminal adenoma arising in the middle ear. The prognosis of these tumors is relatively bad because of their potential malignancy and the tendency for recidivation. Recommendations for treatment are deep excision, postoperative irradiation in malignant types and regular follow-up visits.
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PMID:[Ceruminoma. Apropos of a case of ceruminal adenoma of the middle ear]. 101 83

Primitive glandular neoplasms of the middle ear are a rare entity. Under this definition epithelial neoplasms are classified according to structure as adenomas or adenocarcinomas, with intact tympanic membrane. Review of the literature shows that four histopathological patterns can be identified among these neoplasms: adenoma, adenocarcinoma, ceruminous adenoma and ceruminous adenocarcinoma. The present work describes a case of primitive ceruminous adenoma of the middle ear (6 cases have been reported in the literature) discovered during exploratory tympanotomy performed on a presumed otitis media which had not responded to medical treatment. The case description is followed by a review of the literature on the subject. The rarity of such neoplasms arises from this review as well as the fact that the histogenesis of ceruminous neoplasms of the middle ear is not clearly defined. Further study is required and more reports need be made in order to establish the best therapeutic approach to such neoplasms. It is the authors' opinion that the term "ceruminoma" is a generic term and not a clear definition and that its use in labeling the most various neoplasms of the middle and external ear must be abandoned.
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PMID:[Glandular tumors of the middle ear: a case of primary ceruminous adenoma]. 228 79

Three cases of primary adenomas of the petrous bone are presented and compared to an adenoma arising from the external ear canal. In contrast to other adenomatous tumors, these caused slowly progressive inner ear symptoms without other signs, hence making differentiation from other benign lesions difficult. In one case, association with von Hippel-Lindau disease is suspected because of a strong family history and recent discovery of a similar lesion in the opposite ear. Bone destruction was found radiographically and clinically with vascular tumor tissue and cysts permeating the bone, causing adjacent bone destruction and remodeling. The histopathologic examination demonstrated this to be a benign process, however, with no direct tumor invasion or other signs of malignancy. Subtotal petrosectomy is a proven approach for complete removal of these tumors. Review of the literature revealed no previous reports of benign adenomas originating in the petrous bone.
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PMID:Adenomas of the temporal bone. 305 41

Ceruminoma is a catch-all term that has caused much confusion both in the literature and in clinical practice in regard to the specific histologic diagnosis and proper treatment for tumors arising from the ceruminous glands of the external ear canal. The term ceruminoma has been used in the past to refer to both benign and malignant lesions. To clarify the terminology and better determine appropriate treatment, two cases of benign adenoma of the ceruminous glands along with their histopathologic findings will be presented. The specific characterization of the individual types of ceruminous gland neoplasms, their clinical manifestations, histopathology, and recommended treatment will then be discussed. Finally, suggestions for the appropriate nomenclature for these rare tumors will be reviewed.
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PMID:Ceruminoma revisited. 343 12

We review the normal anatomy and discuss characteristic findings of soft-tissue abnormalities of the external auditory canal (EAC). The indications for computed tomography (CT) of the temporal bone have been significantly expanded with the inclusion of soft-tissue abnormalities of the external ear and the auditory canal. Soft-tissue abnormalities of the EAC that can be evaluated with CT include atresia, edema, hemorrhage, fracture, posttraumatic or infection-caused keloid, malignant external otitis, hemangioma, lymphangioma, papilloma, keratosis obturans, acquired cholesteatoma, adenoma, ceruminoma, fibroma, mixed tumor, sarcoma, and basal cell, squamous cell, or adenocystic carcinoma. CT scans of 25 patients who had soft-tissue abnormalities of the EAC were reviewed. The clinical data were correlated with the radiographic findings. We conclude that CT is the best overall radiographic modality for evaluating the extent and character of soft-tissue abnormalities of the EAC. Significant clinical information that is helpful in patient management decisions is added by this technique.
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PMID:Soft-tissue abnormalities of the external auditory canal: subject review of CT findings. 400 95

Primary middle ear glandular tumors of the adenocarcinoma and adenoma types are rare. The terminology used in describing them is quite varied. Some investigators presume that a distinct recognizable group of these tumors are benign, but because of the rarity of the lesions, such conclusions have been difficult to verify. We review the literature of these lesions and report 11 additional cases. The course was documented in 25 cases in the literature; 20 of these were reported to be benign over periods of follow-up from 1 month to 10 years, and 5 were fatal. Among our patients, 5 had a benign course, 3 died of causes related to the tumor, and 3 had persistence of their lesion and substantial consequent morbidity. We emphasize the slow growth and elusive nature of these lesions. Histologic evidence of mitoses, roentgenologic evidence of bony destruction, and cranial nerve involvement were factors consistent with a poor prognosis. The origin of these tumors may vary. A similarity to paragangliomas is noted. The ultimate course of these tumors cannot always be predicted from the histologic appearance. Early surgical removal appears to be the most successful therapy. Three of the 4 types of glandular tumors of the external ear canal described by Wetli, et al, can be found in the middle ear: adenoma, adenocarcinoma, and adenoid cystic carcinoma. In addition, several other types of glandular lesions can occur in the middle ear--the "choristomas," mucoepidermoid carcinomas, and what we believe to be a variant of paragangliomas. The adenoid cystic tumors are well described in the literature and will not be discussed here. We reviewed cases of the adenoma and adenocarcinoma types, some of which bore a resemblance to the paragangliomas.
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PMID:Adenocarcinoma and adenoma of the middle ear. 716 95

A recurrence of a parotid pleomorphic adenoma presenting as an external ear canal mass is reported. The route of extension was radiographically documented as an incompletely closed foramen of Huschke. The historical and developmental features of this foramen and the mechanisms of tumor extension as they relate to it are discussed.
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PMID:Recurrent pleomorphic adenoma of the parotid gland involving the osseous external auditory canal. With a note on the foramen of Huschke. 922 61

A system for the computerized differentiation of parotid gland tumors is proposed. The parotid gland is the largest of the salivary glands. It is found in the subcutaneous tissue of the face, overlying the mandibular ramus and anterior and inferior to the external ear. The classification system is based on a multifeature tissue characterization approach, using fuzzy inference systems as higher-order classifiers. Baseband ultrasonic echo data were acquired during conventional ultrasound imaging examinations using standard ultrasound equipment. Several tissue-describing parameters were calculated within numerous small regions of interest to evaluate spectral and textural tissue properties. The parameters were processed by an adaptive network-based fuzzy inference system, using the results of conventional histology after parotidectomy as the "gold standard." The results of the classification are presented as a numerical score indicating the probability of a certain tumor or alteration for each parotid gland. The score can be presented to the physician during examination of the patient to improve the differentiation between various types of parotid gland tumors. The system was evaluated on n = 23 cases of patients undergoing radical parotidectomy. The receiver operating characteristic curve area is A(ROC) = 0.95 +/- 0.07 when using fourfold cross-validation over cases and differentiating between various benign parotid gland tumors and monomorphic adenoma.
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PMID:Sonohistology for the computerized differentiation of parotid gland tumors. 1622 31

A carcinoma ex pleomorphic adenoma was diagnosed in the left mandibular salivary gland of an 8-year-old female spayed dog. The animal presented with a large nonpainful swelling in the left submandibular region. A computed tomography scan detected an irregularly enhancing soft tissue mass that was closely associated with the left external ear canal and extended to the left wing of the atlas. On surgical exploration, the mass was intimately associated with the left mandibular salivary gland. Both the mass and the adjacent gland were removed, and the diagnosis was determined by histopathology. The tumor was comprised of basaloid and low columnar epithelial cells, many glandular units formed by well-differentiated sebocytes, and multifocal regions of necrosis, mineralization, and hemorrhage. Salivary gland tumors with sebaceous differentiation are very rare in animals, with one previously reported case in a cat.
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PMID:Carcinoma ex pleomorphic adenoma with sebaceous differentiation in the mandibular salivary gland of a dog. 1667 88

Chondroid syringoma of the external ear canal is a rare, usually firm or polypoid tumor, representing the cutaneous counterpart of pleomorphic adenoma of salivary glands. We report a very rare case of chondroid syringoma in a 40-year-old man who presented with a fluid-containing cyst in the external ear canal. Clinical and radiological examinations showed involvement of the whole external canal to the annulus. The cystic lesion was totally excised along with the overlying skin. The postoperative course was uneventful.
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PMID:Chondroid syringoma of the external ear canal presenting as a cyst. 1676 21


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