Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0001418 (adenocarcinoma)
 68,496 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Eleven adult sheep of various breeds were examined due to inspiratory dyspnea. Fiberoptic examinations conducted in 8 of the sheep revealed masses to be obstructing the nasal passages. Identification of the masses through histopathologic examination showed 7 to be adenocarcinomas, 1 a papillary adenoma, and 4 were cases of glandular hyperplasia with lymphoplasmacytic infiltration (nasal polyps). One ewe had both an adenocarcinoma and a polyp. Surgical removal of the masses was attempted on 6 of the sheep. Four of the 6 surgically-treated sheep have survived between 2 mo. - 2 years without recurrence of the obstruction.
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PMID:Naturally occurring nasal obstructions in 11 sheep. 398 95

A 53-year-old woman with polycystic disease was admitted because of abdominal distention and dyspnea. Percutaneous puncture was performed and adenocarcinomatous cells were seen in the contents of the main liver cyst. A right hepatic lobectomy was carried out, and a hard nodule was found to arise from the wall of the main liver cyst. Microscopically the nodule was poorly differentiated adenocarcinoma and CEA was seen both in the epithelium of the liver cyst and in the tumor cells by the PAP method. We consider that the tumor originated in the cyst of the polycystic liver. Five similar cases were reported up to 1984.
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PMID:[Carcinoma originating in a hepatic cyst of polycystic disease--a case report]. 398 89

A 65-year-old woman was admitted to the hospital because of dyspnea. 15 years previously biopsy of an enlarged left cervical lymph node revealed giant-follicle lymphoma; the patient received radiation. 7 years before a right radical mastectomy was performed for an adenocarcinoma of the breast; there were metastases to several anxillary lymph nodes. 4 years before, a malignant lymphoma was discovered again and radiation successfully given. 5 months before admission there was an onset of severe dyspnea. Upon admission, the temperature was 36.9 degrees C, pulse 100, and respirations 32. Blood pressure was 120/70. Oxygen, prednisone, furosemide, chlordiazepoxide, and morphine were administered. The woman died the 2nd day. Clinical diagnoses showed that the woman died of carcinoma of the breast with metastoses to mediastinal lymph nodes, the chest wall and the lungs, and that lymphoma was inactive. Radiation may have caused the late malignant tumor. A late radiation-induced complication may be another malignant tumor. It is noted that radiation therapy may be a calculated risk in some cases.
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PMID:Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 47-1972. 450 38

An aged beef cow had a primary lung tumor that was diagnosed postmortem. Clinical signs included inappetence, weight loss, coughing, dyspnea, and reduced lung sounds. Antibiotic treatment was ineffective. The cow was euthanatized. Postmortem examination revealed numerous, firm nodules throughout both lungs. Microscopically, the pulmonary nodules contained neoplastic cells and the diagnosis was bronchiolar adenocarcinoma. A diagnosis of pulmonary neoplasia, although rare, should be considered in an aged cow with similar historical and clinical findings.
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PMID:Bronchiolar adenocarcinoma in a cow. 609 37

Twenty-four thyroid carcinoma patients with infiltration of the trachea were treated surgically. The histological diagnosis in these cases included papillary adenocarcinoma in 22 different patients, medullary carcinoma in one patient, and undifferentiated carcinoma in one patient. In 19 of the patients hemoptysis was noted, and dyspnea was present in ten patients. In 14 of the 24 patients the carcinoma was diagnosed by radiographs of the neck, while in seven patients it was demonstrated bronchoscopically. In three patients tracheal infiltration by thyroid carcinoma was diagnosed by biopsy of the tracheal wall at operation. When the tracheal wall was infiltrated by thyroid carcinoma, treatment consisted of circumferential resection of the involved segment of the trachea followed by an end-to-end anastomosis. Of the 24 patients, 17 survived and six died. In the 17 patients who survived, 13 were disease free. Of this number, six survived more than five years after the initial tracheal resection.
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PMID:Resection of the trachea infiltrated by thyroid carcinoma. 706 53

Pulmonary tumor thrombotic microangiopathy (PTTM) is characterized by widespread fibrocellular intimal proliferation of the small pulmonary arteries and arterioles in patients with metastatic carcinoma. Microscopic pulmonary tumor emboli have frequently occurred in patients with malignant tumors; however, few cases of PTTM have been reported. A rare case of a patient with gastric adenocarcinoma who presented with acute dyspnea and lethal respiratory failure is described. Histologically, diffuse fibromuscular intimal thickening causing luminal stenosis and obstruction but containing rather few cancer cells was observed in the small pulmonary arteries and arterioles. These findings were consistent with PTTM. Although PTTM is a rare phenomenon, PTTM should be considered in the differential diagnosis of acute dyspnea or pulmonary hypertension in patients with carcinoma.
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PMID:Pulmonary tumor thrombotic microangiopathy. 758 35

The finding of a cardiac tamponade (CT) as initial manifestation of lung cancer is rare, being its most frequent manifestations dyspnea, cough and edemas. The presence of alithiasic acute cholecystitis (AAC) as early manifestation of CT is extremely rare, despite this having being described related to other situations of low cardiac output. We present the case of a patient who underwent emergency surgery due to AAC as a form of presentation of CT, this being the initial manifestation of a pulmonary adenocarcinoma. The histopathological study of the liver and the vesicle were compatible with signs of short evolution venous stasis, and the diagnosis was established through pericardium biopsy and thoracic CAT.
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PMID:[Acute acalculous cholecystitis complicating the presentation of cardiac tamponade as the initial manifestation of a pulmonary carcinoma]. 774 16

A case of extensive bone marrow infiltration due to gastric cancer is reported. A 65-year old man with an acute episode of anemia (Hb 4.1 mg/dl) and dyspnea was admitted to the Medical Department of a general hospital. Bone marrow biopsy showed extensive paratrabecular infiltration of a poorly differentiated adenocarcinoma of gastric origin. The primary tumor in the stomach was confirmed, and the patient was referred to our Institute and treated with combination chemotherapy (FAMTX) for 6 cycles. Due to the disappearance of bone marrow infiltration, the patient was considered for curative resection of the primary gastric cancer. After 27 months the patient is alive and in clinical complete remission.
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PMID:Gastric cancer with bone marrow invasion at presentation: case-report and review of the literature. 775 48

We analyze the clinical characteristics, the diagnostic criteria and the radiological aspects of 10 cases of Carcinomatous Lymphangitis. The quickly progressing exercise dyspnea and the constitutional syndrome were the most frequent symptoms. In nine patients, the tumor was previously unknown. The image methods (adbominal CAT and Echography) and the fibrobronchoscopic exam allowed a correct diagnosis. The most frequent neoplasia had a pulmonary origin and the most frequent histology was adenocarcinoma. The histological tests (bronchial and transbronchial biopsies) were more effective for the diagnosis than the cytological test (bronchoalveolar lavage, bronchoaspiration and bronchial brushing), although these were complemented. The radiology showed a reticulo-linear pattern in all the cases. The finding of macroscopic disorders in the fibrobronchoscopy, the presence of a local infiltration or a node/mass image in the thoracic radiography were highly suggestive of primary pulmonary neoplasia.
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PMID:[Carcinomatous lymphangitis. Clinical study of 10 cases]. 777 83

Unilateral absence of the left pulmonary artery is a rare congenital anomaly that may remain unrecognized until adulthood, in which case it may lead to inappropriate diagnosis and management. The authors describe a case in which a patient came to their institution with dyspnea and a chest roentgenogram showing a prominent right pulmonary artery, right aortic arch, and a left lung mass accompanied by ipsilateral volume loss. Although the initial evaluation suggested a differential diagnosis that included thromboembolic pulmonary disease and vascular compression by tumor, further workup revealed unilateral absence of the left pulmonary artery accompanied by left lung hypoplasia, and interestingly, ipsilateral emphysema and adenocarcinoma. The embryologic factors responsible for this abnormality and how it may potentially affect the development of emphysema and adenocarcinoma are discussed.
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PMID:Case report: congenital absence of the left pulmonary artery accompanied by ipsilateral emphysema and adenocarcinoma. 787 25


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