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Query: UMLS:C0001175 (AIDS)
 120,706 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

As HIV-related prophylactic and therapeutic research findings continue to evolve, the Health Resources and Services Administration (HRSA) of the Public Health Service has created multidisciplinary mechanisms to disseminate new treatment options and educate primary care providers at rural and urban sites throughout our nation's health care system. HRSA has implemented (a) the International State-of-the-Art HIV Clinical Conference Call Series, (b) the national network of AIDS Education and Training Centers, (c) the nationwide HIV Telephone Consultation Service, and (d) the Clinical Issues Subcommittee of the HRSA AIDS Advisory Committee. These collaborative and comprehensive efforts at HIV information dissemination target physicians, nurses, physician assistants, dentists, clinical pharmacists, mental health care providers, case managers, and allied health professionals. The sites where they provide care include public health clinics; county, State and Federal correctional facilities; private practice offices; community and academic hospitals; military and Veterans Administration facilities; hemophilia centers; schools of medicine, nursing, and dentistry; departments of health; chronic care facilities; visiting nurse and home care agencies; health maintenance organizations; and Indian Health Service clinics and hospitals.
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PMID:Educating primary care providers about HIV disease: multidisciplinary interactive mechanisms. 819 Aug 53

The author presents the stimulation effect of arttherapy offered to schizophrenic patients, professional and amateurs painters--members of The Art Club of the Outpatients Clinic in Gdynia. The author shows the progress of arttherapy in the medical care not only for the psychiatric patients, but also for the chronically and terminally ill and for other people staying on long term basis in care houses, e.g. suffering from AIDS. The aim of the paper is to illustrate the positive changes in condition, familial and social status among schizophrenic patients--amateurs and professionals painters, members of "The Art Club" of the Outpatients Clinic in Gdynia. They were encouraged by therapists having the possibility of exposing their work in 9 public painting exhibition and by the collaboration with similar clubs in Poland and Belgium. One very interesting example of artist creator--whose work was exhibited at the Art Gallery in Brussels was discussed. The author observed an influence of this type of rehabilitation on club members in their private life, and stresses the very positive influence of art therapeutic stimulation on the family and social life of the chosen patients.
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PMID:[Art therapy as a stimulation in the process of social adjustment of schizophrenia patients]. 820 63

Rafael Rodriguez is an artist, activist, and Puerto Rican humanist. As an artist, he has explored various media, including drawing, painting, collage, recycled art and sculpture. He won first prize at the Woodstock Art-Rock Fair in 1969, and had exhibitions at the 1964-65 World's Fair in New York. He uses his art to expose fights for social injustice on a political level. In 1987, Rafael was diagnosed as HIV-positive. After a period of depression, he found in education the strength to rise above his fears and take control of his life. He now lives and works in New Jersey at a facility for persons living with AIDS. He became founder of the Red Ribbon Fellowship, and works with countless other organizations. He has recently returned to his art, which was on hold, as a means of conveying to the community his ideas and preoccupations. In 1987 he created five works which comprise his series called Anguish. They express life and death, the sacred and the profane, and the substance and the emptiness. Rafael uses various elements and diverse religious beliefs in a visual and plastic global vision of humanity and the individual.
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PMID:[Rafael Rodriguez: artist and activist]. 1136 43

Nan Goldin, a photographer whose life has been greatly affected by AIDS, speaks out about the backlash against her work, after the opening of her exhibit, I'll Be Your Mirror, at the Whitney Museum of American Art. Much of Goldin's work involves photographs depicting alternative lifestyles, risque materials, or photos taken in places where AIDS has a more subtle presence, if any at all. She plans an exhibit on hospices soon.
J Int Assoc Physicians AIDS Care 1997 Mar
PMID:Nan Goldin reflects: "I'll be your mirror". Interview by Brandon Judell. 1136 24

The transformation of AIDS art from the early days of the epidemic to the present is examined, from the powerful expressions of rage and in-your-face images of sexuality to a new AIDS art form expressing more reflective expressions of challenged survival. Art's influence in reflecting the truth about AIDS as envisioned by advertising agencies of pharmaceutical companies is explored, particularly Positively Art. The 14-month calendar with each month reflecting a facet of AIDS by artists who are HIV-infected is produced by Visual AIDS. Profiles of several artists reveal their struggle with the disease as expressed in their art and the therapeutic value of this art. Positively Art is viewed by the AIDS community as providing a degree of validation of the truth about themselves and the disease. Abbott Laboratories, the company sponsoring the calendar, is considering the continuation of their sponsorship on an annual basis.
J Int Assoc Physicians AIDS Care 1998 Feb
PMID:Truth & art in the new age of AIDS. 1136 86

Fungal infections have become important causes of morbidity and mortality in immunocompromised hosts, including those with the acquired immune deficiency syndrome (AIDS). Although significant therapeutic advances are being made in the field of antiretroviral therapy, parallel advances must be attained in the management of secondary infections, including those due to fungi. As increasing numbers of people with HIV infection come in to medical attention, the problem of fungal infections will also increase, requiring innovative approaches toward understanding the pathogenesis of these infections and developing new diagnostic and therapeutic modalities. A better understanding is required for the immunopathogenesis of fungal infections. Improved understanding of new and established antifungal agents in conjunction with ART agents as well as immune modulators, should yield important advances in prevention, control and treatment of fungal infections of HIV infected people.
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PMID:Recommendations for fungal opportunistic infections prevention in persons infected with human immunodeficiency virus. 1184 56

The chronically HIV-infected cellular reservoir in lymphoid tissue (LT) represents a formidable obstacle to the long-term success of antiretroviral therapy. Cytoreductive chemotherapy with cyclophosphamide (CTX) reduces cells in LT, and we hypothesized that coadministration of antiretroviral therapy with CTX may diminish the cellular reservoir over time. Ten antiretroviral treatment-naive subjects were recruited, and they received stavudine, lamivudine and nelfinavir (antiretroviral therapy, ART) until 2 consecutive plasma HIV RNA levels measured < 50 copies/ml (step 1). Five subjects then received ART alone, whereas five subjects received ART plus three escalating doses of CTX (step 2). Viral DNA was measured in LT obtained by excisional lymph node biopsy and peripheral blood mononuclear cells (PBMCs), using quantitative polymerase chain reaction at three time points in both groups (before steps 1 and 2, and after CTX). Viral DNA declined in both groups after the initiation of ART alone in step 1. During step 2 both groups experienced a modest decline compared with step 1. However, no significant differences were observed in viral DNA in LT or PBMCs between the ART alone and the ART plus CTX groups. Suppression of plasma HIV RNA levels < 50 copies/ml was not maintained in the ART plus CTX group, perhaps because of inadequate medication adherence. The group receiving ART plus CTX had lower CD4(+) lymphocyte counts and absolute total lymphocytes compared with the ART alone group. We conclude that the addition of CTX to ART did not diminish the cellular reservoir in HIV-infected persons.
AIDS Res Hum Retroviruses 2002 May 20
PMID:Addition of cyclophosphamide to antiretroviral therapy does not diminish the cellular reservoir in HIV-infected persons. 1203 83

Students from the Department of Fine Art and Performing Arts of Chancellor College were subcontracted to spend one month in Nyambi and one month in Gawanani to facilitate participatory research and information gathering from the villages using focus group interviews. Nyambi is an Islamic-dominated area, while Gawanani is Christian-dominated. Music and drama were used to mobilize the communities. Performances were followed by discussion of how traditional practices potentially increasing the community risk of HIV infection could be altered. A drama presentation with proposed solutions was then presented to each community. Major risk factors identified were promiscuity and commercial sex, traditional male circumcision conducted with nonsterile equipment, female initiation requiring young women's participation in sexual intercourse, the sexual cleansing of young widows, tattooing by traditional healers, and misconceptions about how HIV is transmitted. Furthermore, extramarital relationships lead to marital breakdown and the subsequent involvement of unsupervised children in exploratory sexual activities. The district AIDS coordinator facilitated meetings with community leaders to mobilize them to form local AIDS committees. The committees then identified volunteers within their areas who were trained in AIDS education and group discussion skills. 58 volunteers were trained in January 1995. Further plans include the additional training of the volunteers in counseling and home-based care skills, transformation of the volunteers groups into self-administered local nongovernmental organizations, the provision of income-generating activities skills, condom promotion, and the application of the project method in other areas in the district. The success of this project attests to how people, when given the opportunity and guidance, can respond positively to problems and tackle them in their own context.
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PMID:Community participation in AIDS activities in two pilot areas, Machinga district, Malawi. 1229 Aug 50

The role of the Vietnam Youth Union (21 million members) is to educate the youth aged 14-28 years about the movement at the grassroots level. Since 1995, it has been entrusted with information, education, and communication (IEC) activities (implemented through the Educational Center for Population, Health, and Development) concerning family planning, the environment, human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). Mass media, direct communication, Youth Union leading staff, Youth Union cultural and arts activities, and advertisement have been used. 16 newspapers and magazines, a radio program, and a TV program disseminate information for the group. 1000 motivators' groups, 1370 Youth Clubs, and Youth Villages at the commune level work to enhance awareness and to change biased attitudes and habits. Leading staff speak at conferences and seminars that are attended by target groups. Art troupes perform at special local events; plays are organized and videos are shown. The HIV/AIDS information and prevention campaign is of great importance because research findings indicate that many young people believe that only prostitutes and drug addicts can be infected, and that condoms are bad and only for use with prostitutes. There are about 2300 persons infected with HIV in 14 provinces, mostly in the south and central regions. 131 are reported to have developed AIDS.
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PMID:Enhancing young people's awareness. 1232 Mar 23

We studied the pattern of HIV-1 DNA development and the association to other HIV-related factors during long-term supervised therapy interruption (LT-STI). Fifteen patients were treated with long-time protease inhibitor-based antiretroviral therapy (PI-ART). They had HIV-1 RNA at <50 copies/ml over 33.4 (SD 9.5) months and CD4(+) cell counts of 875 (SD 415) x 10(6)/liter. A real-time polymerase chain reaction, amplifying fragments of the HIV-1 pol gene and the human albumin gene simultaneously, was used to quantify HIV-1 DNA molecules in CD4(+) cells. The quantity of HIV-1 DNA in CD4(+) cells increased during LT-STI in all 15 patients, with an average doubling time of 2 months. Tentatively, three patterns were observed: rapid initial increase with subsequent stabilizing levels, rapid continuous increase, and slow increase. The HIV-1 DNA slope was positively related to the HIV-1 RNA maximum and steady state level and the baseline HIV-1 DNA value. It was inversely related to the decrease in CD4(+) cells both before the start of PI-ART and during the LT-STI. To conclude, HIV-1 DNA persists in infected CD4(+) cells despite long-term effective PI-ART and will increase after therapy interruption. The most important clinical predictor of long-term STI failure was the rapid CD4(+) cell decline before PI-ART. In patients with a steep pre-PI-ART slope it may be prudent to continue treatment and not initiate therapy interruption.
AIDS Res Hum Retroviruses 2003 Apr
PMID:HIV type 1 DNA development during long-term supervised therapy interruption. 1280 1


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