Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000737 (abdominal pain)
 31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 10-years old girl with chronic pancreatitis, in whom the symptoms of acute pancreatitis appeared after gastroduodenal endoscopy is described. One hour after endoscopy the following symptoms appeared: unigastric and epigastric pain, intense vomiting, elevated amylase activity in the serum (2744 micro/l) and in urine (23738 micro/l) as well as serum lipase activity (4350 micro/l). Ultrasound of the abdomen revealed the enlargement of the pancreas with hypodense structure in comparison to the examination conducted couple hours earlier, and trace of fluid around the pancreas. In the treatment intravenous omeprazole, a strict diet and intravenous fluid and electrolytes were administered. After two days vomiting and abdominal pain subsided, biochemical results improved and the reduction of pancreas dimensions in ultrasound study was observed.
Pol Merkur Lekarski 2008 Jan
PMID:[Acute pancreatitis as a complication of diagnostic gastroduodenal endoscopy at 10 years old girl--case report]. 1863 46

Variable clinical manifestations of toxocarosis and poor availability of diagnostic tests cause this disease often misdiagnosed. Here, we present a 17-year-old male patient with atypical toxocarosis. The only symptoms of the disease were diarrhoea, vomiting and abdominal pain. Diagnostic procedures revealed leucocytosis, high eosinophilia, increased level of C-reactive protein and seromucoid as well as hydrothorax and ascites. In addition, gastroscopy of the upper gastrointestinal tract demonstrated numerous erosions of gastric and duodenal mucous membrane with concomitant inflammation, but without Helicobacter pylori infection. IgG antibodies against Toxocara antigens were detected by ELISA in the patient's serum. During the 4-month follow-up period spontaneous improvement was observed with disappearance of hydrothorax and ascites, reduction of blood eosinophilia and decrease of Toxocara antibodies titre. It could be concluded, that because of a wide spread of Toxocara sp. in environment and frequently atypical manifestation of toxocarosis, this disease should be taken into consideration in every patients with eosinophilia of unknown origin. Moreover, broader availability of diagnostic tests to detect toxocarosis is warranted.
Pol Merkur Lekarski 2008 Jun
PMID:[Atypical manifestation of toxocariasis in 17-year-old boy--a case report]. 1870 37

In the article, 17-year-old girl with iatrogenic severe hipercalcemia was presented. The girl was treated since the age of 12 years for steroid-sensitive minimal change disease. Due to steroid therapy osteoporosis developed and intensive treatment with active form of vitamin D and high doses of calcium was started. She was admitted to our clinic in severe general state with abdominal pain, vomiting, dehydration, muscle weakness, hypertension and mental confusion. Severe hipercalcemia with nephrocalcinosis was diagnosed. The history revealed that the girl had increased the doses of drugs intentionally. The authors emphasized the need for careful monitoring of prophylaxis and treatment for osteoporosis due to steroid therapy.
Pol Merkur Lekarski 2008
PMID:[Severe hypercalcemia as a complication of intensive treatment for osteoporosis due to steroid therpay in 17-year-old girl with the nephrotic syndrome]. 1892 9

Hepatitis C is caused by the hepatitis C virus (HCV) infection. According to World Health Organization data, 3% of the world population (approximately 170 million people) is infected with HCV; in Poland there are over 700,000. Over 70% of those infected manifest no symptoms in the acute phase of the disease, and in about 70-80% the acute phase progresses into a chronic form. Patients with symptoms in the acute phase of HCV infection most commonly present with unspecific signs and symptoms that may develop in other viral liver infections, e.g. malaise, fatigue, abdominal pain, mild hepato- and splenomegaly and arthralgia. These symptoms usually persist for 2 to 12 weeks. In the chronic phase a subset of patients complain of malaise, nausea, abdominal pain and itching. With time, chronic hepatitis C may develop into liver cirrhosis. The basic diagnostic methods in HCV infection involve determination of anti-HCV antibodies using the ELISA immunoassay and examination of HCV-RNA with the RT-PCR method. The current treatment of HCV infection involves administration of pegylated interferon a and ribavirin over a period of 48 weeks in HCV-1 genotype infection, and 24 weeks for HCV-2 and 3 genotypes. Effectiveness of therapy depends on the HCV genotype. HCV elimination can be achieved in 78% of patients with HCV-2 and 3 genotypes, and in 55% of patients with HCV-1 genotype.
Pol Arch Med Wewn 2008 Dec
PMID:Viral hepatitis C. 1920 52

A 54-year-old male patient developed acute onset of chronic aortic dissection manifesting as primarily abdominal pain. A prompt diagnosis was made and urgent surgery was carried out successfully under profound hypothermic circulatory arrest. Prompt surgery is mandatory for such patients in order to prevent abrupt rupture. The awareness of possible aortic dissection is the key point leading to an early diagnosis in patients with atypical presentations.
Kardiol Pol 2009 Feb
PMID:Acute onset of chronic aortic dissection presenting as abdominal pain. 1928 80

Inflammatory fibroid polyp of the stomach is a rare benign mass of unknown etiology, mostly located within the pyloric area. Histopathological findings mainly reveal the presence of mononuclear fusiforme cells forming loose extensive bundles or rotary structures of rotated spirals with abundant amount of eosinophilic cytoplasm. These cells are negatively stained for S-100 protein and desmine and positively stained for CD-34. Symptoms of the disease depend on the localization and the size of the polyp. We report a case of 50-year-old woman with a large inflammatory fibroid polyp with a diameter of 60 x 50 x 40 mm imitating benign gastric tumour. She mainly suffered from abdominal pain and lab tests revealed symptoms of severe anaemia. We performed partial gastrectomy with Hofmeister-Finsterer modification. Postoperative pathological findings certified sings of inflammatory fibroid polyp. During the two year followup period we did not report any signs of recurrence or dissemination. Clinical manifestation of large inflammatory fibroid polyp of the stomach can imitate symptoms of gastric cancer. Partial gastrectomy with an unaltered, healthy wall margin of 2 to 3 cm is sufficient, curative treatment modality in such cases.
Pol Merkur Lekarski 2009 Feb
PMID:[Inflammatory fibroid polyp of the stomach--a case report]. 1938 17

Lactose malabsorption and milk products intolerance symptoms are the most common alimentary tract disorders. Lactose intolerance is a result of lactase deficiency or lack of lactase and lactose malabsorption. Three types of lactase deficiency were distinguished: congenital, late-onset lactase deficiency and secondary lactase deficiency. Lactose intolerance means the appearance of clinical gastrointestinal symptoms after ingestion of lactose. To the clinical symptoms of lactose intolerance belongs: nausea, vomiting, abdominal distension, cramps, flatulence, flatus, diarrhea and abdominal pain. The diagnosis of lactose intolerance is based on the breath hydrogen test and analysis of lactase activity in the small intestine mucosa. Dietary treatment eliminates clinical symptoms.
Pol Merkur Lekarski 2009 Feb
PMID:[Lactose intolerance: pathophysiology, clinical symptoms, diagnosis and treatment]. 1938 23

The pathomechanism of Helicobacter pylori action upon gastric mucosa and its role in the pathogenesis of gastritis have not been fully elucidated. The aim of this study was to evaluate the most prevalent lymphocyte subpopulations of the gastric mucosa in gastritis in children, as well as to evaluate the expression of Fas and Fas ligand receptors (FasL), periapoptotic markers of gastric mucosa lymphocytes before and after H. pylori eradication. Forty nine patients aged 6 to 17 years, investigated due to chronic abdominal pain, were studied. The obtained tissue samples were analysed by immunohistochemistry. Different lymphocyte subsets were quantified on the basis of surface antigen expression (CD3, CD4, CD8, CD20), secreted cytokines (IL-4, IL-6, IFNgamma) and Fas and FasL proteins in the gastric mucosa. B and T helper lymphocytes were found to play a major role in the inflammatory infiltration in the gastric mucosa in children during H. pylori infection. Their expression was found to decrease after eradication. The enhanced expression of Fas receptor on lymphocytes before treatment and a decrease of this expression after eradication of H. pylori were shown. It was demonstrated that there is a correlation between CD4 and Fas receptor expression that may induce apoptosis of the helper lymphocytes in infected children.
Acta Biochim Pol 2009
PMID:Helicobacter pylori increases expression of proapoptotic markers Fas and FasL on CD4 lymphocytes in children. 1957 57

Diverticular disease it is one from the most common disease, and the number of young people with this illness is increasing last time. It is connected with our life style: without physical activity and low-fiber diet. Main symptoms of diverticular disease can be mild (like: abdominal pain, flatulence, constipations or diarrhea) but can also be connected with serious complications (like perforation or bleeding). The aim of this article was assigning the rules of diagnostics and treatment both mild and severe causes of this illness. Methods of prevention were also presented.
Pol Merkur Lekarski 2009 May
PMID:[Diverticular disease--the rules of management]. 1960 26

Infections with Campylobacter spp. occur as a result of consumption of live cells with food. In developing countries those infections are immensely common, particularly during early childhood and 5 to 10 cases can appear during the initial two years of life. The symptoms appear usually after 1-7 days from infection depending on the number of ingested cells and individual sensitivity. Characteristic symptoms of infections caused by Campylobacter spp. infrequently occurring jointly in the clinical form of the disease include: diarrhea, abdominal pain and increased temperature. In the majority of cases the disease is mild and lasts from 2 to 7 days. Usually Campylobacter are excreted with feces during a period of 7-21 days, sometimes even longer. Occasionally in the increased risk group dangerous complications may occur. They include: bacteremia, meningo-myelitis, neurological disturbances and reactive arthritis.
Pol J Vet Sci 2009
PMID:Campylobacter spp.--a significant microbiological hazard in food. II. Lesions and infection development, pathogenic mechanisms and complications. 1964 63


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