Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000737 (abdominal pain)
 31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In Australia, physicians admitted a 31-year-old woman with a 1-year history of right upper quadrant abdominal pain that had recently radiated to her right shoulder and a 6-week history of swelling over the right lower ribs. She had used an IUD for a total of 10 years. She had a fever and a fast pulse rate. She had a 20 x 20 cm tender, hot, fluctuant mass over the anterior right costal margin with induration nearby. Air entry was minimal at the right lung base. She had low hemoglobin, a high white blood cell count, and a high platelet count. Liver enzyme levels were high. A chest X-ray revealed minor atelectasis of the right lower lobe and a small right pleural effusion. A CAT scan revealed an 8 x 3 cm fluid collection in the extrapleural space beneath the ribs and a 10 x 5 cm collection of fluid indenting the right lobe of liver. Signs of pelvic inflammation were evident. Prior to surgery, intravenous ampicillin, gentamicin, and metronidazole therapy were started. A surgeon incised the abscess, draining 600 ml pus. A catheter was inserted postoperatively to irrigate the area with normal saline so as to complete the drainage. No sulphur granules were seen in the sinus between the ribs. Many neutrophils and a mix of Gram-positive branching bacilli (Actinomyces israellii) and Gram-negative filamentous bacteria (Porphyromonas asaccharolytica) were in the pus. Actinomyces-like organisms were present on a Papanicolaou stained vaginal smear and on a Gram stain of material on the removed IUD. No cultures grew from blood samples. From 2 days to 6 months after surgery, she underwent therapy of amoxycillin/ clavulanic acid 500/125 mg 3 times a day. P. asaccharolytica is usually part of the anaerobic flora of the urogenital and intestinal tracts. Chest wall actinomycosis was a result of distant spread from an IUD-related pelvic infection.
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PMID:Chest wall actinomycosis in association with the use of an intra-uterine device. 785 30

Lately, myeloprolipherative disorders are frequently reported as causes of portal vein thrombosis, probably due to the early detection of latent cases of this condition. We report two patients with portal vein thrombosis that presented with abdominal pain, nausea, vomiting and clinical consequences of portal hypertension such as variceal hemorrhage, splenomegaly and ascites. Diagnosis was made by a CAT scan in one patient and doppler ultrasound in the other. Both patients had high platelet counts and an essential thrombocytosis in the bone marrow.
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PMID:[Portal vein thrombosis associated with essential thrombocytosis. Clinical cases and review of the literature]. 900 49

A patient with a history of epigastric abdominal pain and occasional vomiting is presented. During the study of an upper gastrointestinal hemorrhage, gastroduodenal invagination secondary to a gastric lipoma of 5.5 cm in diameter was diagnosed. Upper digestive endoscopy and gastroduodenal study were not diagnostic. Echography detected a duodenal mass suspect of invagination. CAT diagnosed the lipomatous nature of the tumor. Surgery confirmed gastroduodenal invagination with a gastric lipoma with ulceration in the mucosa which covered the same. Enucleation of the tumor was performed. Histologic study established the diagnosis of gastric lipoma. The post operative period was uneventful. A review of the clinical, diagnostic and therapeutic aspects of this rare disease is reported.
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PMID:[Gastroduodenal invagination and upper gastrointestinal hemorrhage secondary to gastric lipoma]. 929 46

A 13-year-old girl presented to the emergency department with a 5-day history of lower abdominal pain and dysuria that coincided with the onset of her last menstrual period. Menarche occurred 4 months previously and previous cycles were normal. The CAT scan of the abdomen and pelvis revealed a uterus didelphis with obstruction. Abdominal pain was due to hematocolpos and hematometra. The left hemivagina was distended with hematocolpos, and left renal agenesis was also noted. The vaginal septum was removed surgically without complications and she continued to be monitored closely.
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PMID:Lower Abdominal Pain in a Perimenarchal Adolescent. 1036 1

Hemangiomas are frequent benign tumors of the liver. Symptoms (abdominal pain and fullness) are mostly seen in giant lesions. Rupture is the most severe complication, can occur spontaneously, with intraperitoneal bleeding, in 1-4% of hemangiomas and has been described in about 30 cases in the international literature with a high mortality (about 60%). This complication is the principal indication for surgery. Although spiral CAT scan and MR are actually the most efficacious imaging methods for study of liver hemangiomas, after Echography, emergency techniques that allows a simultaneous therapeutic approach--as is angiography--are preferable. Trans-arterial embolization (TAE) is in fact useful to stop bleeding and then to perform a safer surgery. A successful embolization can delay the surgical resection of the hemangioma for the time necessary to recover from the hemodynamic distress. Aside from the success of angiographic approach, surgery remains mandatory, effective in stopping the bleeding and in preventing re-bleeding or other complications of TAE such as abscess, fever, etc.. Intraoperative echography currently is the best method to identify vasculo- biliary anatomy and to perform a correct resection. The absence of risk factors for spontaneous rupture of liver hemangiomas, makes this event unpredictable. The best treatment for non-ruptured hemangiomas is still controversial but surgery is usually limited to symptomatic tumors larger than 10 cm.
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PMID:Spontaneous rupture of a giant hemangioma of the liver. 1101 19

A 27 years old female presented with diffuse abdominal pain, malaise, weight loss and a palpable mass in the left abdomen. Abdominal CAT scan showed a 18 cm heterogeneous tumoral mass that originated in the kidney. The patient was operated on and it was not possible to completely remove the mass. In the postoperative period the patient received chemotherapy with vincristine, cyclophosphamide and adryamicin but the disease progressed and the patient died 16 months later. The pathological study of the surgical specimen disclosed a tumor with monotonous proliferation of small round cells with a basophilic nucleus and scanty cytoplasm with PAS positive granules. Immunohistochemistry was positive for specific neuronal enolase and CD99. Involvement of the urinary system with primary neuroectodermal tumors is very infrequent.
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PMID:[Primitive neuroectodermal tumor of the kidney. A case report]. 1135 72

A 68 years old male presented with right hypochondrium abdominal pain and jaundice with no other clinical finding. CAT Scan and Ultrasonography showed right lobe bile duct dilatation. Magnetic Resonance Cholangiopancreatography gave an outstanding vision of a restricted right lobe bile duct dilatation associated to choledocholithiasis. A right hepatectomy and bile duct exploration were performed. The histopathological study disclosed a Caroli disease associated to a primary cholangiocarcinoma. Caroli disease is a congenital disorder characterized by intrahepatic cystic bile duct dilatation with a high risk association with cholangiocarcinoma.
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PMID:[Primary cholangiocarcinoma associated with Caroli disease]. 1208 Aug 80

A 32 years old female was admitted to hospital due to acute abdominal pain, nausea, vomiting and liquid stools. Physical examination was normal except for pain on her left inferior abdominal quadrant without peritoneal irritation signs. An abdominal CAT-scan suggested thrombosis at celiac trunk, although the echo Doppler showed no alterations except for signs of ischemia in the distal branch of the superior mesenteric artery. An exploratory laparotomy was performed disclosing a necrosis of the distal ileum and cecum, diffuse peritonitis and thrombosis of the ileocecoapendiculocolic artery. No vasculitis lesions were found in the arteries of medium size examined. A history of intermittent claudication for the past 3 years as well as acrocyanosis, asymmetry of pulses and blood pressure in the superior extremities was ascertained after the surgery. A MRI angiogram showed multiple stenoses and irregularities at the celiac trunk, hepatic, superior mesenteric and fibular arteries. No abnormalities at the aortic arch and its main branches were documented. A sepsis due to Candida sp complicated her postoperative period. After recovery, prednisone 1 mg/kg/day was started and the anticoagulation continued. The abdominal pain, intermittent claudication and superior limb acrocyanosis disappeared. This is an unusual case of type IV Takayasu's arteritis with acute abdominal signs as the first manifestation.
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PMID:[Intestinal necrosis as clinical presentation of Takayasu arteritis]. 1249 34

Toxins A and B are known to be the primary virulence factors of Clostridium difficile. Other potential virulence factors have been identified such as binary toxin (actin-specific ADP-ribosyltransferase toxin, or CDT). A retrospective case-control study was performed in order to identify clinical features and risk factors of C. difficile-associated diarrhoea due to binary toxin-producing strains. Each case (a patient with diarrhoea due to binary toxin-producing strain) was compared with two controls (patients with diarrhoea due to a C. difficile strain that did not produce binary toxin) matched for ward and date of hospitalization. cdtA and cdtB genes were screened by PCR. Production of CDT was studied by Western blotting using an antiserum against Ia and Ib from the Clostridium perfringens iota toxin, and the activity of the binary toxin was assessed using an ADP-ribosyltransferase assay. Twenty-six cases (14 males and 12 females) were identified in 1999 and 2000. Cases and controls did not differ significantly for sex, age, previous administration of antibiotics or frequency of endoscopic examination. Diarrhoea was community-acquired more often in cases than in controls (65.4 vs 35.7 %, P = 0.017) and more often represented the cause of hospitalization (61.5 vs 26.2 %, P = 0.003). Moreover, diarrhoea in cases was more frequently associated with abdominal pain (63.6 vs 39.4 %, P = 0.07) and with liquid stools (76.9 vs 59.5 %, P = 0.14) than in controls. These results suggest that there could be a correlation between the production of binary toxin and the severity of diarrhoea.
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PMID:Clinical features of Clostridium difficile-associated diarrhoea due to binary toxin (actin-specific ADP-ribosyltransferase)-producing strains. 1567 14

We report a 42 years old female that presented with abdominal pain and no palpable mass. Imaging abdominal ultrasound, CAT scan and magnetic resonance showed a solid tumor located in the retroperitoneum. The patient was operated on excising the tumor. Pathological examination of the surgical piece disclosed a retroperitoneal fibromatosis or desmoid tumor. Postoperative evolution of the patient was uneventful and she was discharged 12 days after the surgical procedure.
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PMID:[Retroperitoneal fibromatosis: report of a case]. 1653 67


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