Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000737 (abdominal pain)
 31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Pleomorphic carcinoma is a rare and very aggressive subtype of lung cancer that tends to grow rapidly and invade adjacent structures. Here we report a case of pleomorphic carcinoma with rapid growth, multiple metastases, and intestinal perforation. A 46-year-old man was admitted to our hospital because of lung abscess. Several antibiotics were administered for 2 weeks, but his condition did not improve. F18-fluorodeoxyglucose positron emission tomography revealed high uptake in the right lung, stomach, and pancreas. CT-fluoroscopic lung biopsy was performed, and a diagnosis of pleomorphic carcinoma was made. His performance status worsened each day, and the lung tumor grew within 1 month. In addition, sudden severe abdominal pain and tenderness developed 10 days after lung biopsy. He was diagnosed with gastrointestinal perforation, and he underwent surgery. However, he died 2 weeks after the surgery. Autopsy revealed the presence of an enormous tumor in the right lung and multiple metastases in the stomach, duodenum, intestine, bilateral kidneys, pancreas, gallbladder, right adrenal gland and thyroid.
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PMID:Pleomorphic carcinoma showing rapid growth, multiple metastases, and intestinal perforation. 2449 66

A 76-year-old woman with a history of hypertension and dyslipidemia was admitted to our hospital because of chest pain. On the basis of an electrocardiogram showing ST elevation in V1-3 leads, the patient was diagnosed with acute anterior myocardial infarction. Coronary angiography (CAG) revealed occlusions of the mid portion of the left anterior descending artery (LAD) and distal portion of the left circumflex artery (LCX). A paclitaxel-eluting stent was implanted in the LAD. Two weeks later, the patient complained of abdominal pain. A computed tomography (CT) scan showed a perivascular cuff around the abdominal aorta and F18-fluorodeoxyglucose positron-emission tomography with CT (FDG-PET/CT) scan showed increased tracer uptake around the abdominal aorta and aortic arch, suggestive of retroperitoneal fibrosis. The second CAG, performed on day 46, revealed occlusion of the posterolateral branch of the LCX and rapidly progressing stenosis of the proximal portion of the LCX. The patient was suspected of coronary arteritis and received oral corticosteroid therapy. The third CAG, performed on day 77, revealed occlusion of the posterior descending branch of the right coronary artery. The corticosteroid therapy was gradually tapered after discharge. The fourth CAG, performed 5 months later, did not show progression of the coronary lesions.
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PMID:Rapid progression of coronary artery disease in a patient with retroperitoneal fibrosis. 3054 9

We present a case of a 38-year-old man with a prior episode of fever of unknown origin (FUO) four years ago who presented with acute severe dull nonradiating abdominal pain centered in the epigastric region associated with nausea and vomiting. Bloodwork showed a normal leukocyte count but elevated erythrocyte sedimentation rate of 26 and elevated C-reactive protein of 40; syphilis titers and anti-neutrophil cytoplasmic antibodies (pANCA and cANCA) were negative. CT angiogram (CTA) of the abdomen and pelvis showed diffuse medium vessel vascular inflammation. Indium-111 labeled leukocyte scan did not show evidence of infection and, specifically, no evidence of infectious vasculitis. Subsequent F18-FDG PET/CT scan showed diffuse uptake in the mesenteric vasculature in the area of abnormality seen on prior contrast-enhanced CT and confirmed the diagnosis of vasculitis, subsequently deemed by rheumatology to be most consistent with segmental arterial mediolysis.
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PMID:F18-FDG PET/CT Diagnoses Vasculitis after a Negative Indium-111 Leukocyte Scan. 3248 80