Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000737 (abdominal pain)
 31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The correspondents describe a case of acute pancreatitis 2 months after starting oral contraceptives in a 32-year-old obese, virilized woman whose familial hyperlipidemia was discovered during hospitalization. She was hospitalized for violent abdominal pain twice; on the second admission laparotomy permitted a diagnosis of typical hemorrhagic acute pancreatitis. When tested a few weeks later, her blood lipids varied from 14-54 gm per 1, triglycerides from 5-32 gm per 1, cholesterol 3-6 gm per 1, pre-beta-lipoprotein peak fell between 50 and 68%, and chylomicrons were absent. Since hyperlipidemia is not known to be assoicated with pancreatitis, the crisis was probably due to oral contraceptives.
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PMID:[Letter: Acute pancreatitis and hyperlipemia under oral contraceptives]. 484 28

A 15-year-old boy with a medical background of obesity, familial hyperlipidemia and acute recurrent pancreatitis, presented to emergency department reporting a 3-day course of periumbilical abdominal pain and nausea. Pain was noticed on epigastric palpation. Laboratory evaluation revealed leucocytosis, neutrophilia and pancreatic enzymes elevation more than three times the upper limit of normal. An acute recurrence of pancreatitis was diagnosed, was admitted to the hospital, being discharged after 5 days. Four days after, he was readmitted because of symptoms recurrence. Elevation of transaminases, gamma-glutamyltransferase (GGT) and direct bilirubin were noticed. Pancreatic enzymes still elevated but lower than in the previous episode. An endoscopic ultrasound revealed a Wirsung with a cephalic stricture and diffuse structural abnormalities suggestive of chronic pancreatitis. The patients was submitted to endotherapy with several sessions of endoscopic retrograde cholangiopancreatography including stenting and pancreatoscopy with marked clinical and imaging improvement. A genetic variant was identified.
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PMID:Chronic pancreatitis in children: treat like an adult? 3175 27