Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0000737 (abdominal pain)
 31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Mucocele of the vermiform appendix was the term formerly used to describe all mucin-secreting lesions of the appendix. In actuality, there are three distinct clinicopathologic entities based on histologic differences. These are mucosal hyperplasia, cystadenoma, and mucinous cystadenocarcinoma of the appendix. Mucosal hyperplasia is usually an incidental finding during laparotomy for an unrelated condition. The case presented herein differed in that the patient had a three-month history of abdominal pain with nothing to suggest the presence of appendicitis, and a 3-cm opacification overlying the right iliac bone on x-ray.
Dis Colon Rectum 1988 Sep
PMID:Mucosal hyperplasia (mucocele) of the vermiform appendix. Report of a case. 316 87

Eighteen cases of mesenteric panniculitis of the colon collected from the literature, together with two cases from the authors' source, were reviewed. The disease occurred most often in late adult life, with a male predominance. Symptoms were abdominal pain, diarrhea, constipation, and a lower abdominal mass in most patients. Barium enema disclosed narrowing, shortening, and poor extensibility of the colon, and ultrasonography and computed tomography showed thickening of the mesocolon and colonic wall with soft-tissue density. Exploratory laparotomy was done in all patients, and colectomy, colostomy, or other surgical treatments were performed in 17 (85 percent). Gross appearance at the time of surgery was characterized by a marked thickening or a firm mass of the mesocolon with a puckered surface involving the appendices epiploicae of the colon. Microscopically, degeneration of the adipose tissue, revealed by aggregates of lipid-laden macrophages, was diagnostic. Inflammatory infiltration and fibrosis also were present in many patients. Mesenteric panniculitis of the colon seems to be a lesion more advanced than the same condition of the small intestine, and colostomy or bypass surgery may be needed for alleviation of severe symptoms.
Dis Colon Rectum 1987 Dec
PMID:Mesenteric panniculitis of the colon. Review of the literature and report of two cases. 331 50

The aim of this study was to determine the prevalence of various kinds of bowel behavior and symptoms thought to be indicative of colorectal cancer in people randomly selected from the community. A probability sample of 330 dwellings in the inner western suburbs of Sydney yielded 202 completed interviews with occupants aged 30 years and older. Eight percent reported annoying abdominal pain that had lasted for two weeks or more in the preceding six months, while 19 percent reported a feeling of incomplete evacuation at least once every two weeks. Blood on the toilet paper was reported by 14 percent and blood in the toilet bowl by 2 percent. Twenty-one percent said they always looked at their stool in the toilet bowl and 34 percent always looked at the toilet paper after using it, but 43 percent seldom or never looked at either their stool or the paper. Of the 75 who said they looked at their stool about half the time or more, two (3.1 percent) reported seeing blood during the preceding six months. Symptoms that may be associated with colorectal cancer are common in apparently well adults. Whilst this includes bleeding from the rectum in toto, it may not be true for blood seen specifically in the toilet bowl. Because this latter symptom has potential discriminating value, it may be worthwhile to promote public education encouraging people to inspect their stools regularly, and to visit their doctor if blood is seen.
Dis Colon Rectum 1986 Apr
PMID:Bowel symptoms in an apparently well population. 348 35

A young male with a penetrating chest wound suffered modest and transitory hemorrhagic shock. Nonocclusive right-sided ischemic colonic necrosis developed secondarily. This became obvious on serial follow-up examinations, prompting exploration and curative surgical resection. This case represents ischemic colitis secondary to hemorrhagic shock following trauma. Upon review of the literature, only five other such cases have been reported. Although shock-associated ischemic colitis is well documented, it is extremely uncommon to see gangrenous changes of the bowel in young, otherwise healthy, trauma victims. Mesenteric vasospasm is believed to be the causative factor in these cases. For unknown reasons, the right colon seems to be the favored site of ischemic damage. Nonocclusive intestinal ischemia should be considered in patients who have abdominal pain after a hypotensive episode.
Dis Colon Rectum 1987 Feb
PMID:Nonocclusive ischemic colitis secondary to hemorrhagic shock. 380 16

We have undertaken a prospective randomized trial of one month's antimicrobial therapy for patients with symptomatic relapse of Crohn's disease. Criteria for entry included two major symptoms: fever, abdominal pain, diarrhea, weight loss, abdominal mass or complications (excluding perianal disease); and two hematologic abnormalities: hemoglobin, ESR, albumin, C reactive protein, iron, or total iron binding capacity. Patients were monitored for the aforementioned clinical and hematologic (hemoglobin, albumin, CRP) parameters over six weeks and for changes in fecal flora. Randomization was to four groups: metronidazole alone (M), cotrimoxazole alone (C), metronidazole and cotrimoxazole (C plus M), or double placebo (P). Seventy-two patients entered the study (18 = M, 16 = C, 21 = C plus M, 17 = P). After two weeks, improvement was reported as follows: M = 67 percent, C = 17 percent, C plus M = 71 percent, P = 35 percent. In the metronidazole group, two patients required surgery and one had troublesome side effects. In the cotrimoxazole group, two had side effects. In the combined group (C plus M), four had troublesome side effects and two of the placebo group (P) required operation. By four weeks, there was no difference in response among the groups: (M = 44 percent, C = 62 percent, C plus M = 57 percent, P = 41 percent). Antimicrobials had no effect on fecal flora or hematologic parameters. These results indicate that antimicrobials have little therapeutic potential for relapse of intestinal Crohn's disease.
Dis Colon Rectum 1985 Feb
PMID:Antibiotic therapy for treatment in relapse of intestinal Crohn's disease. A prospective randomized study. 388 64

Twenty-five patients were operated on at the Brigham and Women's Hospital for colonic diverticulitis complicating treated renal failure during the period 1951 to 1983. Twelve patients had functioning renal allografts (eight cadaver, four living-related); 13 were on dialysis therapy. Six patients had polycystic kidney disease. The majority of patients had acute abdominal pain. Four had histories of chronic abdominal pain; nondiagnostic exploratory laparotomies were performed on two of these patients, who developed localized tenderness. The overall mortality in this series was 28 percent, with sepsis being the most common cause of death. Six of seven patients who died had free colonic perforations at surgery. Mortality correlated with age, with six of 14 patients (43 percent) over age 50 dying, as compared with one of 11 patients (9 percent) under age 50. There was no correlation between survival rate and type of surgery performed, dose of prednisone or azathioprine used, or type of treatment received for renal failure.
Dis Colon Rectum 1985 Nov
PMID:Surgery for diverticulitis in renal failure. 390 14

Since the turn of the century, the elderly population, particularly those over the age of 80, has been increasing steadily. Consequently, the surgeon will be confronted frequently with the diagnostic challenge of acute appendicitis in this population. Over the past ten years, 13 patients over the age of 80 were treated for acute appendicitis at the St. Lukes-Roosevelt Hospital Center. The mean duration of symptoms was 2.4 days; all patients complained of abdominal pain, with 72 percent of patients having right lower quadrant involvement. Ninety-two percent had perforated prior to surgery, and 23 percent did not survive the disease. This high mortality rate is attributed to both a delay in presentation to the physician and a further delay in proper treatment due to misdiagnosis. This is a disease with which every physician must be familiar and be continually vigilant, as correct diagnosis and prompt treatment are the keys to averting high morbidity and mortality rates.
Dis Colon Rectum 1986 Mar
PMID:The diagnosis and treatment of acute appendicitis in the aged. 394 30

Neutropenic enterocolitis, also known as typhlitis or ileocecal syndrome, is a recognized complication of the treatment of hematologic malignancies and usually is fatal. The pathologic findings consist of bowel-wall ulcerations and necrosis with bacterial or fungal invasion. These findings are usually limited to the ileum, cecum, ascending colon, and appendix. The syndrome occurs in a select patient population who generally have 1) a hematologic malignancy, 2) neutropenia, 3) thrombocytopenia, 4) a recent course of chemotherapy, and 5) a recent course of antibiotics. This syndrome also can arise spontaneously in patients with aplastic anemia or cyclic neutropenia. The clinical presentation consists of a high fever and right-sided abdominal pain with evidence of peritoneal irritation. Recommended therapy is right hemicolectomy.
Dis Colon Rectum 1986 Mar
PMID:Management of the ileocecal syndrome. Neutropenic enterocolitis. 394 36

In a prospective study of 402 colorectal cancer patients, 133 patients (46 men and 87 women) presented with right colon cancer. There was no significant difference between men and women in right colon cancer incidence. Common presenting features were abdominal pain, weight loss, and anemia. Ninety-one patients underwent resection with curative intent. There were significantly fewer Dukes' A tumors in the right colon cancer series (P less than 0.05). Significantly more women in the right colon cancer group were over 70 years old (P less than 0.05). The findings of peritoneal metastases and poorly differentiated lesions at initial surgery also were associated significantly with women who had right colon cancer (P less than 0.05). This study confirms previous reports of more advanced tumors in the right colon. The need for age, sex, and subsite differences to be taken into account when assessing treatment outcomes or survival is emphasized.
Dis Colon Rectum 1986 Apr
PMID:Age and sex differences in right colon cancer. 394 13

A case report of sclerosing mesocolitis is presented. This is an unusual and poorly understood entity. A 49-year-old woman presented with episodic abdominal pain and a palpable abdominal mass. A fibrotic mass causing extensive compression of her cecum and transverse colon was found at laparotomy. The pathologic findings and treatment of sclerosing mesocolitis are discussed.
Dis Colon Rectum 1986 Apr
PMID:Sclerosing mesocolitis. 394 20


<< Previous 1 2 3 4 5 6 Next >>