Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000737 (abdominal pain)
 31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Yersinia enterocolitica was isolated from the feces of 29 patients over a three-year period following the introduction of a selective culture medium. Y. enterocolitica was the third most common enteric pathogen after Campylobacter jejuni and Salmonella in this series of 3795 specimens from a predominantly adult population. The isolation rate of Y. enterocolitica was 0.9% and this represented 15.8% of positive cultures. The usual symptoms of Yersinia infection were diarrhea (93%) and abdominal pain (72%), often associated with tenderness in the right iliac fossa and fever. Fourteen patients required admission to hospital and four came to surgery for possible appendicitis. Acute terminal ileitis and mesenteric lymphadenitis were noted in each case. Two patients who were HLA-B27 positive had a reactive arthritis as their dominant complaint. In conclusion, Y. enterocolitica has emerged as a common cause of diarrhea in adults. It is an important cause of symptoms resembling those of acute appendicitis and is occasionally complicated by reactive arthritis.
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PMID:Clinical aspects of infection with Yersinia enterocolitica in adults. 330 48

Yersinia enterocolitica causes primarily ileocolitis in human beings, and is manifested by abdominal pain, diarrhea, and fever. Usually, it is a self-limiting disease. Local or systemic complications are rare. A 71-year-old man with Y enterocolitica colitis complicated by perforation and abscess formation is described. This complication is very rare, and the four other cases that have been reported in the literature are reviewed.
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PMID:Yersinia enterocolitica infection complicated by intestinal perforation. 330 74

By auramine and modified Ziehl-Neelsen staining, cryptosporidial oocysts were found in the stools of 31 (1.36%) out of 2,367 patients with diarrhoea. All specimens were also tested for Salmonella, Shigella, Campylobacter, Yersinia, and Rotavirus. Among these patients, 432 were children and 24 (5.5%) of them were positive for cryptosporidia. All children infected with cryptosporidia were immunocompetent. Watery diarrhoea, vomiting and abdominal pain were the most frequent symptoms. The survey showed that in patients with gastroenteritis, cryptosporidial oocysts were found more commonly in the stools of children than in those of adults, and the prevalence of infection was the highest in August and September (16 cases). The epidemiological aspects and clinical significance are discussed.
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PMID:Cryptosporidial diarrhoea in children. 343 76

An 8-year-old boy presented with elevated temperature, malaise, hepatosplenomegaly, mesenteric adenitis, and septic shock. Cultures of biopsied abdominal lymph nodes as well as the blood grew Yersinia pestes. The boy's condition improved after two weeks of chloramphenicol and cefotaxime (Claforan). Two days after stopping intravenous antibiotic therapy, the patient again became febrile and complained of abdominal pain. Abdominal imaging with 111In-labeled leukocytes did not show any abnormalities, however, 67Ga-citrate scintigraphy demonstrated an abnormal focus of increased radiopharmaceutical uptake within a confluence of necrosed lymph nodes within the right upper quadrant of the abdomen. In addition, abnormal 67Ga-uptake was seen within the left hip region. Correlative imaging with computed tomography is also presented.
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PMID:Imaging in plague. 366 83

Children admitted with abdominal pain were studied prospectively to determine the incidence of Yersinia infections. The three proven cases in a series of 65 children reflected the variation in severity of the illness. Specific stool culture was the most useful method of detecting the organism. Management of ill children with abdominal signs, for whom no diagnosis can be reached, should include treatment for Yersinia infections.
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PMID:Yersinia infections: a cause of abdominal pain in childhood. 371 9

Yersinia enterocolitica was cultured from feces of 122 symptomatic adults in a single facility using selective culture media; all isolates were confirmed in an independent reference laboratory. Of 128 isolates, multiple serotypes were defined and all were biochemically typical for Yersinia enterocolitica. Other agents were seen in 20 patients; of these, seven were Yersinia fredriksenii and six were Clostridium difficile. Diarrhea (80%) and abdominal pain (64%) were common, whereas other features such as fever (9%) and bloody stools (8%) were unusual. Use of antibiotics (24%) or opiates (28%) in the month before culture was common. The terminal ileum was seen radiographically in 20 patients, but only two barium studies showed abnormalities. Fiberoptic endoscopy and biopsy studies, done in greater than 50% of the cases, showed minimal or no changes in most patients. However, 3 patients had pseudomembranous colitis with concomitant Clostridium difficile cytotoxin and 7 had diffuse severe colitis. New culture techniques, and possibly geographic differences, have contributed to the high isolation rates of this organism. Yersinia enterocolitica occurs sporadically, involves a variety of serotypes, and is associated with a broader clinical spectrum than was formerly appreciated.
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PMID:Gastrointestinal features of culture-positive Yersinia enterocolitica infection. 378 Nov 77

Clinical and laboratory findings of 78 paediatric patients with infections due to enteroinvasive bacteria were analysed. The material included 33 cases of Yersinia enterocolitica, 21 of Campylobacter jejuni, 21 of Salmonella and 2 of Shigella infection, reflecting the current order of frequency ot these enteropathogens in Finnish paediatric population. Diarrhoea was the presenting symptom in 73% of the cases with Yersinia, 90% with Campylobacter and 100% with Salmonella. Conversely, abdominal pain on admission occurred more frequently (p less than 0.01) in patients with Yersinia (68%) than with Campylobacter (38%) or Salmonella (24%). Diarrhoea caused by each of the three enteric bacteria was clinically indistinguishable, with gross blood and mucoid stools occurring in most of the cases. However, faecal leucocytes were more frequently present in diarrhoea due to Y. enterocolitica (87%) and C. jejuni (83%) than Salmonella (36%); p less than 0.025). Diarrhoea due to Y. enterocolitica was typically associated with signs of systemic response, including fever greater than or equal to 39 degrees C, WBC count over 11 X 10(9)/l, and C-reactive protein greater than or equal to 10 mg/l. These criteria may thus be helpful in differentiating Yersinia infections from other cases of exudative diarrhoea in children. The clinical picture of Y. enterocolitica infection probably reflects the more invasive nature of this enteropathogen as compared with C. jejuni or Salmonella.
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PMID:Clinical and laboratory features of Yersinia, Campylobacter and Salmonella infections in children. 388 48

We report two cases of focal lymphoid hyperplasia (FLH) of terminal ileum in adult patients. Both cases showed identical morphological findings. The first was discovered during cholecystectomy in a 75-year-old woman who complained mild non-specific abdominal discomfort. The second was manifested by right lower quadrant abdominal pain in a 32-year-old man. The surgical specimens revealed a thickened wall, a narrowed lumen and multiple ulcerations. The histologic features were small cell, well differentiated lymphocyte infiltration, with several follicles showing large germinal centers; regional lymph nodes revealed a conspicuous reactive size enlargement. Further clinical investigations revealed no other abnormalities. Clinical course showed benign evolution after 6 and 3 years of respective follow-up. FLH should be differentiated from terminal ileum inflammatory and infectious diseases. It can be differentiated from Crohn's disease by the absence of characteristic histological features; from Yersinia infection by the absence of significant rates of specific serum antibodies. Moreover, FLH can be differentiated from malignant lymphoma by the presence of follicles and enlarged germinal centers and by the long-term benign evolution. The nature of FLH in terminal ileum, as well as those of the stomach and colo-rectum is still to be determined. Several hypothesis are proposed: reactive, benign neoplastic, or prelymphomatous lesion?
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PMID:[Focal lymphoid hyperplasia (pseudolymphoma) of the terminal ileum in adults]. 407 21

While a large number of confirmed cases of Yersinia enterocolitica have been reported in different temperate zones, there is little information on the incidence of this infection in tropical areas. For the first time in Bangladesh, this organism has been isolated from the stool of a diarrhoea patient and, therefore, is recognized as a new enteropathogen in this country. The strain was characterized as biotype I, serotype 0:8 and phage type X2. The patient was a five-year-old girl from a poor Muslim family, and admitted to ICDDR,B's Treatment Centre with complaints of abdominal pain, low-grade fever and diarrhoea.
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PMID:Yersinia enterocolitica infection; a case report from Bangladesh. 409 79

Yersinia pseudotuberculosis infection was diagnosed in 12 children on the basis of recovery of the organism from stool cultures and a 4-fold or greater titer change in agglutinating antibody. Eight of the 12 Yersinia isolates were recovered from stool cultures only after cold enrichment. Clinical findings in 50% or more of patients were fever, rash, diarrhea, desquamation, strawberry tongue, vomiting, red and cracked lips, abdominal pain, arthralgias, hepatomegaly and conjunctivitis. The patients' clinical manifestations and courses of illness resembled those of Izumi fever, an illness that occurs epidemically in Japan. Additionally the finding in two children fulfilled the strict criteria for Kawasaki syndrome, and signs in the other 10 children were consistent with that diagnosis.
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PMID:Yersinia pseudotuberculosis infection in children, resembling Izumi fever and Kawasaki syndrome. 634 44


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