Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000737 (abdominal pain)
 31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Uterine perforation is known to be associated with IUD use. Usually the perforation occurs upon insertion, but the IUD can become embedded in the uterus and later be forced through the wall by uterine contractions. On occasion, IUDs have been noted in abdominal viscera, most often the sigmoid colon. Recently, a 20-year-old black woman was encountered whose Copper-7 IUD had perforated her appendix and had caused chronic appendicitis during pregnancy. The woman had had 3 live-born children and 1 spontaneous abortion. The Copper-7 had been inserted 6 months previously without apparent difficulty. At 21 weeks' gestation, the patient developed right lower abdominal pain radiating to the right buttock. She had no other gastrointestinal complaints, was afebrile, and exhibited no abnormal physical findings to explain her symptoms. Urine cultures were negative. 12 weeks later, the patient developed nausea, vomiting, anorexia, and constipation. She was again afebrile. After spontaneous labor at 40 weeks, the patient was delivered of a normal male infant. Following spontaneous expulsion of the placenta, the uterus was manually explored, and no IUD was found. The patient desired postpartum tubal ligation. An x-ray film of the abdomen revealed a Copper-7 IUD in the right lower quadrant at the level of the iliac crest. During the operation, it was noted that the IUD had apparently perforated the uterus 1 centimeter below the right uterotubal junction. The strings were in the myometrium, but the body of the IUD had passed transversely through the lumen of the appendix and remained embedded in it. The IUD may have induced inflammation in an otherwise normal appendix, and this seems most likely particularly because copper-containing IUDs are prone to cause irritation and adhesion formation.
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PMID:Appendiceal perforation by Copper-7 intrauterine contraceptive device. 729 85

Intrauterine contraceptive device (IUCD) is relatively safe but still with some serious risks. Uterus perforation is rare and would be fatal. A case of Cu-7 IUCD invading into the sigmoid colon through uterine perforation caused by a pelvic blunt trauma was presented. Our case showed that uterus perforation by an IUCD could induce utero-sigmoid fistula which is likely to be missed. Imaging is required when the patients with IUCD present abdominal pain, particularly with a history of trauma.
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PMID:Invading of intrauterine contraceptive device into the sigmoid colon through uterine perforation caused by a blunt trauma. 2676 47

Uterine perforation, a complication of dilation and curettage, is typically recognized immediately after the procedure by clinical symptoms of peritoneal irritation resulting from intraperitoneal bleeding. Our patient complained of having an uncomfortable feeling, slight dizziness, palpitation in the sitting position and abdominal discomfort but did not show signs of peritoneal irritation 24 h after dilation and curettage. However, she suddenly complained of abdominal pain. Tenderness and rebound tenderness were detected at the lower abdominal wall. Ultrasonography and magnetic resonance imaging suggested uterine perforation. When the abdominal cavity was opened, a hematoma under the broad ligament of the uterus, laceration of the side wall of the uterine cervix and a small amount of bloody ascites and small clots in the abdominal cavity were observed. The uterine cervical wall was sutured. Physicians should postpone discharge and observe the clinical course carefully when a patient complains of inexplicable discomfort after dilation and curettage.
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PMID:Bleeding in the retroperitoneal space under the broad ligament as a result of uterine perforation after dilatation and curettage: Report of a case. 2810 22