Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0000737 (abdominal pain)
 31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The sudden drop of circulating estrogen in the premenopausal phase causes somatic and psychosomatic symptoms in women around the age of 40, which necessitates hormonal substitution and also reliable contraception because of the risk of pregnancy owing to irregular cycles. At this age the risks of pregnancy-related thrombosis, hypertension, and diabetes, perinatal mortality congenital anomalies, and maternal mortality are higher. Only 6.3-7.3% of women giving birth are over 35 years of age in Austria, but still 26% of women having an abortion are 36 years old or older. The rate of conception ranges between 2% and 5%, and when it falls below 1%, contraception is no longer necessary (around age 45-49). The IUD is acceptable and safe, and pelvic inflammatory disease does not play a significant role at this age. The most frequent side effects are spotting, hypermenorrhea, lower abdominal pain, and difficulties with intercourse. The introduction of micropills with an ethinyl estradiol dose of under 50 mcg and several agents, such as desogestrel, gestoden, and norgestimate, has made it possible to use them over the age of 40, provided no risk factors, such as metabolic disorders or smoking, are present. However, prior determination of lipid status is required. Sterilization is a final form of contraception when an increase of family size is no longer desired; whether the husband or the wife should be sterilized also poses a question. For female sterilization laparoscopy is used almost exclusively with bipolar diathermy, thermocoagulation, or binding with clips or rings. Hysterectomy is recommended in the case of myomatous uterus with cycle irregularities and hypermenorrhea. The condom, the diaphragm, or the natural temperature, Billings, or symptothermal methods have much higher failure rates. The physician has to advise women about the most suitable method.
 ...
PMID:[Contraception and the climacteric]. 262 31

Eighteen girls with major uterovaginal malformations were admitted to the Pediatric Surgical Service over a 17-year period. The diagnosis was not suspected or delayed in more than one half of the patients. The encountered anomalies were divided into four groups: I, isolated uterovaginal malformations (UVM) (4); II, UVM with anorectal anomalies (8); III, UVM with cloacal (urogenital sinus) abnormalities (5); and IV, caudal twinning (1). Imperforate hymen, vaginal web, low vaginal obstruction, or disorders of gonadal or chromosomal development were excluded. Patients presented with an abdominal mass or distension (5), abdominal pain (4), "sciatic"-like pain (1), purulent vaginal discharge with perineal pain (1), amenorrhea (2), and a pelvic and prerectal mass (1). The introitus was reported as normal in 11 patients with vaginal atresia or agenesis by the primary physician. Diagnostic studies, in addition to clinical and endoscopic examination, included routine radiological workup, genitourinary contrast studies, pelvic and perineal sonography, computerized tomography (CT) scanning, and more recently, magnetic resonance imaging. In complicated UVM, especially vaginal duplications with unilateral atresia, the CT scan was the most helpful diagnostic tool. Laparotomy was necessary, not only for therapeutic, but diagnostic reasons; even so, complex anomalies, such as vaginal duplication with unilateral atresia and a septate uterus, could not be suspected. Treatment was directed toward the restoration of a functional uterovaginal tract and the frequently associated anorectal anomalies. A review indicated that contrary to our expectations, the major UVM occurred in children with a low imperforate anus rather than the high variety.
 ...
PMID:Utero vaginal malformations: a trap for the unsuspecting surgeon. 267 33

A case of myomectomy during pregnancy is presented. Generally myomectomy is contraindicated during this period. On the 14th week of pregnancy our patient presented with progressive lower abdominal pain and a tender mass of nearly 12 centimeter diameter in the pouch of Douglas. Therefore an exploratory laparotomy was performed to exclude torsion of an adnexal mass or pedunculated subserous myoma. A dorsal degenerating myoma with short thick pedicle (4 cm diameter) was found. It was compressed between the promontory of the sacrum and the uterus. Myomectomy was performed and pregnancy progressed without complications.
 ...
PMID:Myomectomy during pregnancy: uncommon case report. 267 53

The aim of the authors was to investigate reliability of method, used by them, for diagnosis of extrauterine pregnancy EP (EP). 123 women with admission diagnosis: obs. graviditas extrauterine were studied retrospectively. It was established that the abdominal pain together with the triad of symptoms from the vaginal-abdominal examination: congested adnexae, enlarged uterus and painful cavum Douglasi were of great diagnostic significance. The highly predicting value and sensitivity of ultrasound examination women with EP emphasized the substantial contribution of echography for early and exact diagnosis, which together with timely operative intervention could contribute to preserve the reproductive capability of women.
 ...
PMID:[Diagnostic problems in extrauterine pregnancy]. 267 91

This is a clinical case report of a 23-year-old female admitted to St Paul's district hospital in North-East Zambia with a chief complaint of abdominal pain. Her past medical history included amenorrhea for 7 weeks, no vaginal blood loss, a previous delivery in 1986, postpartum abdominal pains which lasted for 3 months. On physical examination, she presented with slight anemia, normal temperature, normal blood pressure and a normal pulse. Pressure applied to the lower abdominal area was painful. Vaginal examination revealed an enlarged uterus; the rectovaginal pouch was extremely sensitive to pressure. Hemoglobin level was 8.5% and a pregnancy test was negative. On Laparotomy, a left sided ampullar tubal was found, with the right tube exhibiting an intact elastic swelling in the isthmus. Right salpingostomy was done to shell out the ectopic gestinal tissue and the left salpingectomy was performed to clean the recto vaginal pouch. The diagnosis made was bilateral ectopic pregnancy. The likely etiology was simultaneous ovulation from both ovaries, fertilization and subsequently implantation. The fallopian tubes had been previously affected by postpartum salpingitis.
 ...
PMID:Bilateral ectopic pregnancy: a case report. 273 42

The increasing number of sterilizations among young women with few or no children had increased interest in the development of methods which are simple, effective, cosmetically suitable and which involve the fewest possible sick days and which minimize destruction of the Fallopian tube so that refertilization has the best chance for success. In Denmark the method used most often in laparoscopy with electrocoagulation. Since 1983 the Fredericksberg hospital has exclusively used laparoscopic sterilization with the Filshie clip. A total of 194 women were sterilized during the period Aug. 1983-Aug. 1986. The mark V Filshie clip was applied a few cm from the horn of the uterus with an applicator which was introduced intraperitoneally with a special trocar. The majority of the women were in their 30s with 20% in their 20s and 24% in their 40s. The patients were observed for 16-51 months. There were no operative complications. 2 patients complained of abdominal pain postoperatively and were treated with antibiotics for suspected perimetritis. 1 patient complained of dysuria and pain but recovered spontaneously within 4 weeks. 1 woman became pregnant 11 months after the operation, corresponding to a pregnancy frequency of .5%. Upon resterilization it was found that the left clip had slipped off. None of the patients were refertilized. 13% of the women had had no children; 27%, 1 child; 44%, 2; 13%, 3; and 2%, 4 or more. 52% of the woman had no induced abortions; 26%, 1; 15%, 2; 4%, 3 and 3%, 4 or more.
 ...
PMID:[Laparoscopic sterilization in women using Filshie clips]. 277 86

A case report of a ligamentary ectopic pregnancy that failed to respond to prostaglandin E2 for induced abortion for sepsis at 24 weeks is presented. The 27-year-old nullipara had normal ultrasound findings for gestational age up to 21 weeks gestation. She had consulted at 5 weeks for abdominal pain and bleeding, at 14 weeks again for abdominal pain, shoulder pain and vaginal bleeding, although both times the pain and bleeding resolved spontaneously. She was seen again at 16 and 21 weeks gestation, when ultrasound scans were normal for dates. At 24 weeks, she experienced vaginal discharge of blood and tissue, and was managed as premature rupture of membranes. She became septic 12 days later. She was treated with transcervical PGE2 and iv oxytocin without response for 3 days. Surgical evacuation was successful, but bleeding persisted. During laparotomy she had a large left broad ligament hematoma, a left ruptured uterus, and open left internal iliac artery and vein. These were repaired, and she received 40 units of blood, 8 platelets and 14 of plasma. Only after histology was the diagnosis of ligamentary pregnancy made. The lack of response to PG for abortion should raise suspicion of ectopic pregnancy, although preoperative diagnosis of ligamentary pregnancy is extremely rare.
 ...
PMID:A rare gynecologic contraindication to the use of prostaglandins and oxytocin to induce abortion. A case report. 279 68

A researcher reviewed the January 1984-December 1986 birth and obstetrical records at the University of Nigeria Teaching Hospital in Enugu. During this period, the incidence rate for abruptio placentae was .44% (81/18,215). 56 of these cases were considered mild and 25 were severe. 15/81 cases did not have adequate antenatal care. 49.4% of the cases were in the 26-30 year old age group. The higher the parity of the women the higher the percentage of those with abruptio placentae, e.g., 3.7% for primigravidas and 33.3% for parity or = 5. The leading symptoms included tender uterus (87.7%), abdominal pain (85.2%), and vaginal bleeding (54.3%). Other symptoms included hypertension, shock, and proteinuria. Vaginal delivery accounted for 80.3% of the abruptio placentae births, while cesarean section accounted for 12.4%, vacuum extraction 3.7%, and breech delivery 3.7%. 91.4% of the patients required a blood transfusion with an average of 3 pints of blood/patient. 22.2% of the patients experienced severe postpartum hemorrhage as a result of uterine atony, coagulation failure, or puerperal sepsis. The perinatal mortality rate stood at 58%. None of the 15% of mothers who had severe abruptio placentae had a live infant. 16% of the infants were premature. Since most of the referred patients either did not have any antenatal care or had inadequate antenatal care, it appears that an appropriate measure to reduce the gravity of abruptio placentae would be a wider distribution of excellent antenatal and obstetric management in the rural areas.
 ...
PMID:Abruptio placentae at the University of Nigeria Teaching Hospital, Enugu: a 3-year study. 280 22

A detailed clinicopathologic study of 14 patients with leiomyosarcoms of the uterus was made. Twelve of 14 patients were followed up for 2 or more years. The median age was 49, the youngest patient was 20, and the oldest was 68. The predominant symptoms were abnormal vaginal bleeding and abdominal pain. The preoperative dilation and curettage established the correct diagnosis was 2 of 6 patients (33%). The predominant method of treatment was total abdominal hysterectomy (TAH). Five patients had adjuvant chemotherapy, 4 had adjuvant radiotherapy, 2 patients had chemotherapy and radiotherapy for adjuvant treatment, and one had adjuvant hormonal therapy. The overall cumulative probability of survival rate at 5 years was 29.6%. The mitotic count, margin type, tumor size, and the presence of necrosis did not affect the prognosis. Favorable prognostic features are low pleomorphism, lower staging, and aggressive management.
 ...
PMID:Leiomyosarcoma of uterus: a review of 14 cases. 281 73

A report on the application of standard 2D-FT MR combined with RARE-MR-Urography in a pregnant woman with right sided abdominal pain, dilated upper urinary tract and possible stone or inflammatory disease. This technique visualised the complete obstructed ureter in relation to the surrounding organs (uterus, vessels), allows precise diagnosis of the cause of the obstruction and avoids ionising radiation.
 ...
PMID:[MR of the urinary tract in pregnancy]. 282 66


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>