Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000737 (abdominal pain)
 31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A literature review was undertaken of clinical stuides to determine the frequency of menstrual alterations or various psychosocial effects after surgical tubal sterilization. The most frequently mentioned symptoms following bilateral salpingocalsy or salpingectomy are increased menstrual blood loss, dysmenorrhea, dispareunia, pelvic pain, oligemenorrhea, polymenorrhea, and preclimacteric syndrome in some cases. Uribe and colleagues attributed the high frequency of abdominal pain in tubal occlusions achieved with mechanical devices such as rings to the compression pain produced by uncut nerve edings, which do not occur with electrocoagulation or the Pomeroy technique. Alderman and colleagues found that only 6.5% of their patients experienced increased menstrual flow after sterilization, but Rioux found confirmation of menstrual changes to be difficlut and Chamberlain reported change in 2.6-51% of patients, perhaps related to previous use of contraceptives. Radwanska and colleagues found that patients sterilized by electrocoagulation or tubal ligation had a lower average level of serum progesterone in the midluteal cycle phase, 9.4 +or- 4.7 ng/ml compared to 17.4 +or- 7.1 ng/ml for controls. Donnez found that patients sterilized by electrofulguration had an average of 8.5 +or- 6 ng/ml of progesterone in the midluteal phase compared to 15.4 +or- 6.3 ng/ml for those sterilized using Hulka clips. The largest proportion of women with menstrual alterations or pain were younger, lower parity women who were sterilized for medical reasons. Menstrual changes and pelvic symptoms following sterilization are subjective and difficult to evaluate. Some authors cite the rarity of longterm sequelae of sterilization, but others used radioimmunoassay techniques to demonstrate changes in serum progesterone levels that may be linked to alterations in function of the ovaries or corpus luteum following sterilization. Other authors believe that most negative sequelae could be minimized or eliminated with better patient selection and counseling.
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PMID:[Sequelae of tubal ligation]. 398 87

800 cases of pelvic inflammation (PI) admitted to the Civic Hospital, Ahmedabad, between October 1967 and August 1974 were studied. 772 (96.5) of these cases involved chronic PI (420 of doubtful etiology, 122 postpartum, 76 postabortal, 46 tuberculous, 33 gonococcal, and 75 postinstrumental). A further 28 cases (3.5%) represented acute PI (19 of doubtful etiology, 5 postinstrumental, and 4 postabortal). 87% of cases were 20-35 years of age. The most frequent clinical symptom was some form of menstrual disturbance (polymenorrhea, 14.87%; dysmenorrhea, 13.5%; scanty period, 11.13%; menorrhagia, 13.37%; and irregular, profuse period, 14%). 48% of the women complained of acute or chronic lower abdominal pain, and 31.1% experienced leukorrhea or purulent vaginal discharge. Sterility was found in 25% of cases. 50% of women with acute PI, 37.6% of those with chronic PI, and 6.52% of those with tubercular PI reported regular menstrual cycles. The most common organism isolated was Escherichia coli (38.45% of cases). Other organisms detected included staphylococcus (10.75%) and gonococci (8.61%). No organism was isolated in 33.78% of cases. The response to treatment with various antibiotics and cortisone was considered good in 28% of cases, fair in 37%, and poor or no response in 36%. Patients given a combined therapy of chloromycetin and corticosteroids showed early recovery and complete resolution of inflammatory masses. Follow-up study revealed that menstrual disorders were cured in 57% of cases and abdominal pain was relieved in 53%.
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PMID:Pelvic inflammation (a study of 800 cases). 1232 59