Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0000737 (abdominal pain)
 31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An analysis of 523 Lundh tests performed on 492 patients over a five-year period has been made. The results suggest that the test is a simple, cheap, and reliable procedure for the diagnosis of pancreatic exocrine insufficiency, and is suitable for both specialized units and general hospitals. It is particularly useful in the differential diagnosis of patients with steatorrhoea or obstructive jaundice and can often distinguish between malignant and benign lesions, as well as indicating the site of the obstruction. It is of lesser value in the diagnosis of abdominal pain.
 ...
PMID:The Lundh test in the diagnosis of pancreatic disease: a review of five years' experience. 476 2

An anomalous arrangement of the pancreatobiliary ductal system is usually observed in patients with a congenital choledochal cyst and is represented by a long common channel distal to the pancreatobiliary junction. According to the angle of the pancreatobiliary junction, anomalous junctions can be classified into four groups: right angle, acute angle, complex union, and normal union (presented here in the order of their incidence). The right-angle type tends to have cystic dilatation of the choledochus, whereas the acute-angle type generally has cylindrical dilatation. However, the grade and length of the stenosis on the distal part of the choledochus tend to determine the type of choledochal cyst. Cystic dilatation is usually observed in patients with high-grade and long stenosis, whereas cylindrical dilatation is seen in those with low-grade and short stenosis. Patients with an acute angle junction seem to only suffer from abdominal pain, and those in the complex union group tend to have jaundice and an abdominal tumor. A high amylase level in the bile within the cyst is observed frequently. In patients with obstructive jaundice, however, the amylase level is usually not elevated, because pancreatic juice cannot enter the choledochus.
 ...
PMID:Anomalous arrangement of the pancreatobiliary ductal system in patients with a choledochal cyst. 620 64

The occurrence of both gastrointestinal carcinoid and von Recklinghausen's disease in the same patient is uncommon. There seems to be a predilection for ampullary carcinoids in these patients. This article reports the sixth case, including a review of the literature and a brief discussion of the implications of this finding. A carcinoid tumor should be suspected in any patient with von Recklinghausen's disease presenting with gastrointestinal bleeding, obstruction, abdominal pain, and particularly obstructive jaundice.
 ...
PMID:Von Recklinghausen's disease associated with gastrointestinal carcinoid tumors. 640 32

A patient with a Billroth II resection and Crohn's disease subsequently developed obstructive jaundice and biliary sepsis. Three hepatic duct stones were demonstrated by ERC. After overcoming the obstruction by means of temporary retrograde internal drainage, perfusion of glyceryl-1-monooctanoate-carnosine and bile-acid-EDTA solution (2) was combined with sucralfate instillation into the blind loop via a duodenal tube. During successful treatment of the cholangiolithiasis, no deterioration of Crohn's disease was seen. Secondary effects such as abdominal pain or diarrhoea, were treated symptomatically.
 ...
PMID:Dissolution of biliary duct stones without papillotomy in a patient with Billroth II resection and Crohn's disease. 642 68

Distal common bile duct stenosis was observed in 16 (9%) of 170 alcoholic patients admitted to a Veterans Administration Medical Center in the last five years. The following clinical and biochemical features were significantly more common (P less than 0.05) among the 16 patients with common bile duct stenosis than in 154 without: jaundice, cholangitis, hyperbilirubinemia, alkaline phosphatasemia, pancreatic calcification, and malabsorption. Surgical decompression of biliary tree was necessitated in 13 of 16 cases due to obstructive jaundice in seven, cholangitis in four, portal fibrosis in one, and persistent abdominal pain in one. The mean (+/- SE) time interval between initial serum alkaline phosphatase elevation and surgical intervention was 308 +/- 108 days. Liver histology in eight cases was remarkable for portal fibrosis in seven and biliary cirrhosis in one. These data suggest that distal common bile duct stenosis is a progressive lesion which is quite prevalent in patients with advanced pancreatic disease of alcoholic etiology.
 ...
PMID:Prevalence and natural history of distal common bile duct stenosis in alcoholic pancreatitis. 647 79

Pancreatic pseudocyst is a relatively rare complication of pancreatitis with a reported incidence of 1 to 5 per cent in patients with pancreatitis. The 5-year experience with pancreatic pseudocyst at Saint Francis Hospital and Medical Center and Mount Sinai Hospital has been reviewed in an effort to determine optimum diagnostic and therapeutic techniques. Twenty-eight patients were treated for this problem during the period of June 1976 through June 1981 with one death. All patients had operative therapy, with internal drainage being the procedure of choice. The most common presenting symptom was abdominal pain. The most useful diagnostic study proved to be ultrasonography. Complications occurred in nine patients (32%). These included bleeding, obstructive jaundice, infection, rupture, and recurrence.
 ...
PMID:Pancreatic pseudocyst. 663 97

The presentation of ampullary carcinoma as acute pancreatitis has been documented only in scattered reports but may be more common than is generally appreciated. More typically this uncommon gastrointestinal neoplasm presents with obstructive jaundice, weight loss, anorexia, and nonspecific abdominal pain. A case of ampullary carcinoma is presented in which the clinical features and computed tomographic appearance were those of relapsing, acute pancreatitis. Only after various clinical and radiographic features indicated on ampullary lesion was the etiology of the pancreatitis finally established and a curative resection performed.
 ...
PMID:Carcinoma of the ampulla of Vater presenting as acute pancreatitis. 669 May 7

We report 10 children with chronic relapsing pancreatitis. These patients can be divided into three groups, based on their clinical history, manifestations, and radiographic findings. Group 1 includes four patients with hereditary pancreatitis; these patients have had recurrent abdominal pain since early childhood, and have a positive family history for pancreatitis. Group 2 includes two patients with clinical and radiographic findings similar to those in patients with hereditary pancreatitis but without a family history of pancreatitis. Group 3 includes four patients with fibrosing pancreatitis who had symptoms and signs of obstructive jaundice. Our report emphasizes three points: (1) that chronic pancreatitis does occur in young children and is most commonly caused by hereditary pancreatitis or fibrosing pancreatitis; (2) that endoscopic retrograde cholangiopancreatiography is a safe and valuable tool for the study of pancreatic and common bile ducts; and (3) that surgical intervention is indicated to drain the pancreatic duct in patients with hereditary pancreatitis, and sphincterotomy is an effective therapy for patients with fibrosing pancreatitis.
 ...
PMID:Chronic relapsing pancreatitis in childhood. 683 84

Hemobilia is a relatively rare manifestation of hepatobiliary disease that is usually characterized by recurrent colicky upper abdominal pain, gastrointestinal bleeding, and obstructive jaundice. In most instances, hemobilia presents as complication of liver injury, blunt abdominal trauma, or liver surgery. Other causes are percutaneous diagnostic procedures, hepatic artery aneurysms, inflammatory disease, biliary tract stones, and liver and bile duct neoplasms. The diagnosis of hemobilia is confirmed by endoscopy and selective angiography. Treatment of hemobilia is primarily surgical, with direct exploration of the liver, ligation of the bleeding point, and relief of bile duct obstruction. If liver damage is minimal, nonoperative management may be successful but requires careful observation and serial arteriography.
 ...
PMID:Hemobilia. 702 4

Surgical experience with 9 patients with chronic pancreatitis is reviewed. Vague, atypical abdominal pain and obstructive jaundice were the most common form of presentation. Serum amylase was elevated in less than half the patients. Ultrasound, ERCP, and operative cholangiopancreatography were the most helpful studies. Ampullary or intrapancreatic obstruction were the main indications for operation, and, when relieved, resulted in resolution of symptoms for an average followup of 4.4 yr. Patients with familial and recurrent bouts of pancreatitis should be studied with ERCP to determine if an anatomic lesion is present.
 ...
PMID:Surgical implications of chronic pancreatitis. 716 80


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>