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Query: UMLS:C0000737 (abdominal pain)
 31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This article, reporting 3 case studies of solitary liver nodules, focuses on the discrepancy in the medical literature among various nomenclatures used to describe hepatic lesions and tumors. Case 1 was a 5-year-old girl with an upper abdominal mass; case 2 was a 19-year-old woman, with a 4-month history of contraceptive use, with a hamartoma which was resected; case 3 was a 38-year-old woman, with a 5-year history of oral contraceptive use and a hysterectomized uterus, who presented with abdominal pain 5 years post-hysterectomy. She had a nodule which was biopsied but not resected. All 3 cases, though from dissimilar patient populations, reflected characteristics of focal nodular hyperplasia, and all were reparative in nature. Histologically and vascularly, these nodules appear to be developed from a vascular basis, and the association of these nodules with oral contraceptive use encourages such speculation. Arguments for diagnosing these liver tumors as focal nodular hyperplasia are presented.
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PMID:Solitary liver nodules. 16 1

The case of a 19 yr-old female with abdominal pain, jaundice, and hepatomegaly is reported. A large mass replacing the left hepatic lobe, detected by scintigraphic and angiographic studies and also by means of ultrasound and transhepatic radio-opaque filling, proved to be cystic. A left hepatic lobectomy was performed. Pathologic examination revealed a mesenchymal hamartoma, a rather rare event in view of the patient's age. Prompt recovery followed surgery, and the patient is well and symptomless 1 yr after operation.
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PMID:Mesenchymal hamartoma of the liver. 43 45

A case of splenic hamartoma arising from the upper pole of the spleen and presenting with upper abdominal pain, ascites and pedal edema is presented. Splenectomy was performed. The histopathology, revealed splenic hamartoma of pulposal type.
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PMID:Splenic hamartoma with portal hypertension: a case report. 130 86

A multicystic pancreatic hamartoma is reported in a 20-month-old female who presented with abdominal pain and distention. This appears to be a distinctive lesion not previously characterized in the English language literature. The 9-cm mass consisted of large, irregular lobules of well-formed pancreatic acini admixed with fibrous tissue and fat. Cystically dilated ducts of variable caliber lined by benign epithelium were present. Endocrine cell islets were not evident. Immunohistochemistry and ultrastructural examination illustrated insulin-producing cells diffusely throughout the exocrine tissue as single cells or in small groups. Cells producing other pancreatic hormones were markedly decreased when compared with an age-matched control pancreas and were similarly dispersed. The patient was alive and well without tumor 9 months later. This entity may provide an unusual opportunity for insight into pancreatic organogenesis and pancreatic cellular differentiation.
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PMID:Multicystic pancreatic hamartoma: a distinctive lesion with immunohistochemical and ultrastructural study. 142 59

A 39-year-old Japanese man with a splenic hamartoma who underwent surgery, is reported herein. The patient had a volvulus of the transverse colon and acute Type A hepatitis. His symptoms included fever, abdominal pain and icterus and the serum chemistry showed liver dysfunction and an elevation of hepatitis A antibody levels. Barium enema revealed a volvulus of the transverse colon. Ultrasonogram showed a hypoechoic mass and angiogram showed evidence of stretching of the intrasplenic vessels in the arterial phase and a hypovascular mass lesion in the venous phase. Macroscopically, the tumor was a well-defined, whitish-yellow, hard nodule. Microscopically, the tumor was composed of fibrous scar tissue containing scattered red pulp tissues and the histologic diagnosis was a splenic hamartoma of the fibrous type. The patient's postoperative recovery was uneventful. The clinical features of splenic hamartoma are reviewed in this report and the differential diagnosis is also discussed.
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PMID:Splenic hamartoma: report of a case and review of the literature. 267 8

Cystic tumors of the pancreas are rare, although their detection has become more frequent with the advent of imaging techniques. In most cases, surgical exploration and often resection of the cystic neoplasm is necessary for establishing a definitive diagnosis; resection remains the treatment of choice. This paper describes three patients who underwent surgery because of cystic tumors of the pancreas. Abdominal pain was the main clinical manifestation; abdominal CT showed the cystic tumor in all three cases. Surgical exploration and resection was successfully accomplished in all. The definitive histological diagnoses were serous cystadenoma, multicystic hamartoma, and choriocarcinoma metastatic to the head of the pancreas. To our knowledge, the last two are the first ones with such diseases reported in the literature.
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PMID:[Cystic neoplasms of the pancreas: report of 3 cases presenting diagnostic difficulties]. 777 15

A case is presented of a bile duct hamartoma (von Meyenburg complex) in a 44 year old man being evaluated for abdominal pain. The computed tomography findings suggested micro-abscesses in the liver and a biopsy showed von Meyenburg complex.
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PMID:Computed tomography of von Meyenburg complex simulating micro-abscesses. 794 20

A 7-year-old girl with an unremarkable family history was admitted with complaints of diarrhea containing mucus and blood, abdominal pain, weight loss and fever for 10 months. Although her symptoms, physical examination and laboratory results were highly suggestive of inflammatory bowel disease, radiologic studies and colonoscopy demonstrated multiple colonic polyps. A bilateral and symmetric lamellar periosteal reaction and osteopenia were present on her extremity radiographs. The chest radiograph and thoracic CT scan were normal. The histologic nature of the polyps was determined as hamartoma. One month after subtotal colectomy, the patient's symptoms resolved and she gained 7 kg in weight. The association of generalized juvenile polyposis and hypertrophic osteoarthropathy has previously been described in five cases; arteriovenous malformations were present in four of them. In our case the polyps were hamartomatous and localized in the colon, without associated arteriovenous malformation.
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PMID:Colonic hamartomatous polyposis associated with hypertrophic osteoarthropathy. 807 21

During a seven year period 18 benign small intestinal tumors were histologically documented in patients referred to us for a small bowel study, using a barium infusion technique. These included seven leiomyomas, five adenomatous polyps, two Peutz-Jeghers hamartomas, one myoepithelial hamartoma, one lipoma, one Brunner's gland adenoma and one neurilemmoma. Ten of the patients were women and eight were men, with their ages ranging from 20 to 75 years (mean age 45 years). Presenting symptoms were gastrointestinal bleeding in 12, anemia in 9, abdominal pain in 4, partial intestinal obstruction in 3 and bloody diarrhea in one. The time elapsed from onset of symptoms to radiological diagnosis ranged between one month and seven years (mean time 16 months). Multiple lesions were encountered in four cases and solitary in fourteen. The site of involvement was the duodenum in 3 patients, the jejunum in 8 and the ileum in 7 of them. Main radiological appearances included solitary or multiple intraluminal filling defects, mass effect on neighbouring loops and dilation of intestinal loops proximally to the lesion. The primary tumor, in the form of a mass or other abnormality of the small intestine was identified in all study cases. Correlation with surgical or endoscopic findings showed that radiology depicted all single lesions, whereas multiple lesions were underestimated in one case. The individual morphological changes shown on examination of the resected specimens resembled the appearances on the barium study in all cases. However, enteroclysis missed four out of seven ulcers and a stalk in one of the five pedunculated lesions. A specific tumor-type diagnosis was reached preoperatively in eleven patients, it was suggestive in five and mistaken in two of them. Our experience indicates that enteroclysis is an effective means in evaluating patients with suspected benign small bowel tumors, preoperatively.
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PMID:Benign tumors of the small intestine: preoperative evaluation with a barium infusion technique. 846 75

Benign small bowel tumors seldom cause symptoms, due to the fluid content and distensibility of the small bowel. We herein present the case of a solitary ileal hamartoma causing melena and abdominal pain in a 24-year-old man. The diagnosis of a submucosal ileal tumor was made after performing small bowel barium studies. Surgical treatment was undertaken, and a histological examination of the excised lesion, which showed a partially ulcerated tumor surface and extended from the submucosa to the subserosa, revealed numerous cystic glands of various sizes together with bundles of proliferating smooth muscle cells. Histochemical and immunohistochemical investigations were performed for differential diagnosis, and the tumor features were consistent with a diagnosis of ileal myoepithelial hamartoma. In the literature, small intestinal myoepithelial hamartomas are quite rare and this is the first report of a myoepithelial hamartoma causing melena.
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PMID:Myoepithelial hamartoma of the small bowel: report of a case. 901 65


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